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Nathan Goodyear

Modulation of tumor necrosis factor alpha expre... [Arch Toxicol. 1999] - PubMed - NCBI - 0 views

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    mouse brain model found increased brain TNF alpha as a result of aluminum levels found in drinking water.
Nathan Goodyear

Phthalate-Induced Pathology in the Foetal Testi... [Reproduction. 2013] - PubMed - NCBI - 0 views

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    This study found a 2 fold increased in estradiol levels in rats exposed to phthalates in-utero.  This could have been due to increased aromatase activity and/or xenoestrogenic effect.  This study proposes a link between phthalate exposure in-uteruo, increased estrogen production and testicular dysgenesis syndrome.  Take home: in this model male testicles were altered prior to birth by phthalate exposure.
Nathan Goodyear

Aging and Luteinizing Hormone Effects on Reactive Oxygen Species Production and DNA Dam... - 0 views

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    Interesting rat model finds that stimulation of the leydig cells of the testis by LH induces ROS.  May be one of the mechanisms by which androgen therapy will induce long-term requirement for replacement.
Nathan Goodyear

Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine ... - 0 views

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    Low dietary vitamin D intake associated with increased oxidative stress, NF-KappaB transcription and damage to brain in animal model.
Nathan Goodyear

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvi... - 0 views

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    Animal model finds that disruption of the gut microbiota by antibiotics disrupts the effects of chemotherapy.
Nathan Goodyear

Bisphenol A Exposure during Adulthood Alters Expression of Aromatase and 5α-R... - 0 views

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    animal model, but Bisphenol A shown to increase aromatase production.  This aids the decreased T:E2 ratio that is commonly found in prostate disease.  So, BPA is a xenoestrogen.  BPA is an androgen receptor antagonist and BPA increases aromatase activity.  
Nathan Goodyear

In vivo reactivation of DNases in impla... [J Histochem Cytochem. 2001] - PubMed - NCBI - 0 views

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    IV vitamin C/K3 combination therapy reactivates DNase activity in mouse model of prostate cancer.
Nathan Goodyear

Pancreatic enzyme extract improves survival in muri... [Pancreas. 2004] - PubMed - NCBI - 0 views

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    Abstract of an animal model look at the use of Pancreatic enzyme therapy in the treatment of pancreatic cancer.  
Nathan Goodyear

Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression o... - 0 views

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    Huperzine A reduces EAE, an experimental MS model.  Thus, huperzine A has a anti-inflammatory effect in the brain.  
Nathan Goodyear

http://worldsciencepublisher.org/journals/index.php/JOS/article/viewFile/1186/899 - 0 views

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    IV vitamin C shown to decrease elevated liver enzymes in rat model of lead induced liver toxicity.
Nathan Goodyear

Ginsenoside Rg3 Alleviates Lipopolysaccharide-Induced Learning and Memory Impairments b... - 0 views

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    Rat model induced inflammatory reaction in brain via LPS injection.  The result was impaired memory.  RG3 from panax ginseng was shown to reduce inflammation, TNF-alpha, IL-1beta, cox-2, thus improving memory and cognitive function.
Nathan Goodyear

Protective role of Panax ginseng extract standardized with ginsenoside Rg3 against acry... - 0 views

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    RG3, an extract from panax ginseng, found to protect against the neurotoxin acrylamide.   Also of interest, is that serotonin, corticosterone, T3, T4, estradiol, progesterone and epinephrine were all decreased in this acrylamide rat model.
Nathan Goodyear

Early repeated administration of progesterone improves the recovery of neuropathic pain... - 0 views

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    Very interesting article.  Early Progesterone treatment, in animal model, shown to improve neuropathic pain recovery.  This is by no means the first study to show this.  This has been shown numerous times in TBI, but the timing of therapy was the purpose of this article.  What is very interesting here is that the metabolites implicated here in the recovery are the same metabolites implicated in an increased tumor potential.
blowfish9

Buy the latest models Me PRO Ultra online - Mepro-ipl.com - 0 views

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    Mepro-ipl have finally launched the latest model online of our Homedics Me PRO Ultra . Finally a machine for absolutely all skin tones and [ALL body ALL skin type] Permanent Infra-red Light [IPL] Laser Radio Frequency.
Willow O'Donnell

Feedgy - Willow Medical - Medical Equipment - 0 views

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    A little research can ensure informed selections when deciding to purchase infusion pumps. The more you know about these medical devices, the easier it becomes to choose the exact model and type you require.
Nathan Goodyear

Lead acetate may cause erectile dysfunctio... [Cell Biol Toxicol. 2013] - PubMed - NCBI - 0 views

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    In rat model, Pb reduced NO and contributed to ED.  Of interest, arginine masked the effects of Pb on NO synthase and vitamin C reversed it all together.
Nathan Goodyear

Vitamin D for Cancer Prevention: Global Perspective - 0 views

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    Only abstract available here.  The authors of the this epidemiologic article estimate that 58,000 cases of breast cancer and 49,000 cases of colorectal cancer can be prevented annually by raising levels to 40-60.  The study also points to a new cancer model that Vitamin D has a positive effect at each step.  The acronym is DINOMIT and this stands for disjunction, initiation, natural selection, overgrowth, metastasis, involution, and transition.
Nathan Goodyear

Hypertension induced by methyl mercur... [Toxicol Appl Pharmacol. 1987] - PubMed - NCBI - 0 views

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    Hg induces hypertension in rat model.
Nathan Goodyear

PLOS ONE: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide B... - 0 views

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    Animal model found that low Hg decreased NO availability.  The result is vasoconstriction induced by ROS and hypertension. The hypertension is the result of an activation of the renin angiotensin system.  The importance here is that low Hg levels induced this change.
Nathan Goodyear

Cyclooxygenase inhibition reduces blood p... [Clin Exp Hypertens. 2000] - PubMed - NCBI - 0 views

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    Inhibition of NO production will result in increased COX and thus vasoconstriction in rate model.  Hg has been shown to both inhibit NO synthase and increase COX.
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