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Nathan Goodyear

Erectile dysfunction may be the first clini... [Clin Res Cardiol. 2013] - PubMed - NCBI - 0 views

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    ED may be the earliest of signs for endothelial dysfunction, insulin resistance, and CVD in young men.
Nathan Goodyear

Erectile dysfunction and coronary disease: Evaluating the link - 0 views

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    ED in men precedes cardiovascular disease by 3-5 years.
Nathan Goodyear

Treatment of erectile dysfunction... [J Sex Marital Ther. 2003 May-Jun] - PubMed - NCBI - 0 views

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    l-Arginine with pycnogenol significantly improved ED over l-Arginine alone.
Nathan Goodyear

Access : Impact of the association between elevated oestradiol and low testosterone lev... - 0 views

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    low T and elevated E2 result in ED in men.  The authors conclude that E2 provides an additive effect on that of low T.  Yet, they fail to realize the previous research that high aromatase activity (Testosterone to Estradiol production) causes the low T.
Nathan Goodyear

Arginine and Citrulline A Review of Their Safety and Efficacy for Erectile Dysfunction ... - 0 views

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    nice review on Arginine + citrulline in ED.  Data is limited, but studies suggest improvement with individual therapy.  
Nathan Goodyear

Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction... - 0 views

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    Men with sexual dysfunction found to have higher E:T ratio and higher Estradiol overall.  This was a retrospective study.
Nathan Goodyear

Environmental Erectile Dysfunction: Can the Environment Really Be Hazardous to Your Ere... - 0 views

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    nice review of the link between environment and ED in men.  No direct cause-effect, but association is definitely seen.
Nathan Goodyear

International Journal of Impotence Research - Obesity, low testosterone levels and erec... - 0 views

  • Studies have shown that ED may be an early biomarker of general endothelial dysfunction, atherosclerosis and CVD
  • testosterone treatment of hypogonadal young and older men improves sexual function, increases lean mass and decreases fat mass
  • In men with low serum testosterone (for example, <8 or 230 nmol l−1) with obesity, metabolic syndrome and diabetes mellitus, treatment with testosterone is warranted
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  • In obese middle-aged men, testosterone treatment reduced visceral adipocity, insulin resistance, serum cholesterol and glucose levels
  • testosterone replacement has a favorable impact on body mass, insulin secretion and sensitivity, lipid profile and blood pressure in hypogonadal men with the metabolic syndrome as well as type 2 diabetes mellitus
  • Testosterone significantly inhibits lipoprotein lipase activity, which reduces triglycerides uptake into adipocytes in the abdominal adipose tissue
  • testosterone treatment decreased endogenous inflammatory cytokines (tumor necrosis factor-α and IL-1β) and lipids (total cholesterol) and increased IL-10 in hypogonadal men
  • Testosterone treatment reduced leptin and adiponectin levels in hypogonadal type 2 diabetic men after 3 months of testosterone replacement
  • available data clearly show a relationship between obesity, low testosterone levels and ED
  • Obesity adversely affects endothelial function and lowers serum testosterone levels through the development of insulin resistance and metabolic syndrome
  • Metabolic disturbances as well as production of cytokines and adipokines by inflamed fat cells may be causal factors in the development of ED
  • The onset of ED and the associated risk of CVD may be delayed through lifestyle modifications that affect obesity, such as diet and exercise
  • Very low testosterone levels contribute to the development of ED in obesity, metabolic syndrome and type 2 diabetes mellitus
  • Obesity is associated with low total testosterone levels that can be explained at least partially by lower sex hormone-binding globulin (SHBG) in obese men
  • epidemiological studies have shown a negative correlation between BMI and total testosterone and to a lesser extent with free and bioavailable (biologically active) testosterone levels
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    Obesity is associated with low Testosterone and ED in men.
Nathan Goodyear

The Association of Exercise with Both Erectile and Sexual Function in Black and White M... - 0 views

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    Highly active men report better sexual function/performance than less active men, though less active men were not found to have ED or sexual dysfunction.
Nathan Goodyear

Chronic kidney disease and erectile dysfunction - 0 views

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    Zinc deficiency implicated in ED in men.  In addition, zinc supplementation improves ED in men.
Nathan Goodyear

Androgens and penile erection: evidence for a direct relationship between free testoste... - 0 views

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    testosterone replacement in men found to improve penile blood flow and thus improve erectile function.
Nathan Goodyear

Relationship between Testosterone and Erectile dysfunction - 1 views

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    Though Testosterone plays a role, it's role in the erectile process is overblown.
Nathan Goodyear

Erectile dysfunction and depression in patients with chronic lead poisoning - Gonulalan... - 0 views

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    chronic lead toxicity linked with increased ED in men.
Nathan Goodyear

PLOS Medicine: Erectile Dysfunction Severity as a Risk Marker for Cardiovascular Diseas... - 0 views

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    As ED is a cardiovascular problem, it is no surprise that those with ED have an increase in CVD.
Nathan Goodyear

Physical activity and exercise for erectile dysfunction: systematic review and meta-ana... - 0 views

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    review study points out that exercise, predominantly cardio, improved ED in men.
Nathan Goodyear

Testosterone Treatment and Sexual Function in Older Men with Low Testosterone Levels: T... - 0 views

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    new study finds that men >65 with low libido and Testosterone levels < 275 increase sexual function with Testosterone therapy.  Only libido was improved; no benefit to erectile function was noted--note that is likely due to depleted NO.  Given time that should improve with he increase in NO synthase and thus NO.  I have a fault with on elf the comments on this study: they point out that increased free Testosterone and estradiol levels were associated with improved sexual activity.  This lacks an understanding of the physiology.  In men with low T > 65, the majority are dealing with inflammation and excess weight; all of which increase aromatase activity and thus estradiol activity.  This does not indicate that an increase in estradiol activity is associated with improved libido in men.  How can elevated estrogen levels lead to low T and then increase levels are associated with improved libido?  This is merely a reflection of the body's dysfunctional physiology.  This observation of increased estradiol by no means shows cause and effect.  Scientists need to due a better job in vetting what they write!
Nathan Goodyear

Is erectile dysfunction a low-grade systemic inflammatory condition? - 0 views

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    ED is the result of low-grade, chronic inflammation.
Nathan Goodyear

Endocrine milieu and erectile dysfunction: is oestradiol-testosterone imbalance, a risk... - 0 views

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    This article points to the impact of T:E2 on ED in men.  A declining T:E2 increases ED in older men.  
Nathan Goodyear

Total Testosterone Levels and the Effect of Sildenafil on Type 2 Diabetics with Erectil... - 0 views

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    Interesting study. In this study group, 36% of type II diabetes with ED had low Testosterone.  This fits with the estimated 40% of those with Diabetes have low T. What is really interesting about this study is that the degree of improvement with ED by Sildenfafil was dependent on the Testosterone level in the low T group.  Meanining that Testosterone therapy in these men would probably be more of a therapy directed at the cause and not Sildenafil.  Of course, the Testosterone therapy would benefit glucose regulation as well documented in the literature.
Nathan Goodyear

Peripheral neuropathy: an underdiagnosed cause of erectile dysfunction - Vall... - 0 views

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    Study links peripheral neuropathy and ED in men.  Though, both are likely a reflection of low Testosterone as elevated aromatase activity.
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