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gut bacteria balance associated with obesity.  The balance of ones gut bacteria plays a significant role in whether a high fat,western diet leads to obesity or not.

HFD found to alter gut bacteria with increase in weight gain.  A return to normal diet did not see a return to the previous gut bacteria balance.  Subsequent HFD resulted in a significantly higher weight gain than the first.

Gut bacteria brain connection: animal study finds antibiotics early in life alter gut flora which effects young brain and alters behavior; probiotics with Lactobacillus rhamnosus JB-1 appears to blunt the altered Gut bacteria brain connection.

Gut bacteria may play crucial role in systemic inflammation that leads to Alzheimer's and Parkinson's disease.  These amyloid production bacteria trigger systemic inflammation that leads to microglia activation and amyloid in the brain.   More establishment of the gut-brain connection.  

Only abstract available here: Gut bacteria, lactobacillus reuteri, could be the key to colon cancer prevention through inflammation control.  What is fascinating is how the gut bacteria influenced epigenetic expression of histidine decarboxylase to increase histamine production.

This article discusses how an imbalance gut bacteria balance leads to endotoxemia and resultant obesity and diabetes. So, the balance of gut bacteria plays a role in obesity. Really changes ones view of how the body interacts and how disease develops through dysfunction.

Not that I am proposing gastric bypass for weight loss.  IN my mind that is like a lobotomy for headache.  But, this study shows the link between gut bacteria and obesity.  This study documented an increase in the expression of certain bacteria types in the gut.   This was associated with increase in white adipose tissue gene expression.  Linking directly the gut and fat.

It is proposed that the balance of bacteria in the gut play a critical role in energy utilization and obesity. This study showed that bypass surgery altered the gut bacteria to favor weight loss: decrease in firmicutes species. But, do we really need gastric bypass to do that? Of course not. Probiotics will do the same.

good review of dysbiosis, commensal bacteria and gut health.

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Study suggests that healthy bacteria, in this study lactobacillus, are important in controlling opportunistic bacteria. 

Non-medical study finds that probiotics can be used to eliminate pathogenic bacteria.  These probiotics release bactericidal and/or bacteriostatic chemicals that can eradicate/control pathogenic and opportunistic bacteria in aquaculture.  This same logic should be applied to the Gut as well.

to be read review on commensal bacteria and metabolic disease link

good discussion of commensal bacteria interaction with immune system.

Gut bacteria proximity, not just balance and diversity, to mucosa lining linked to systemic inflammation and insulin resistance in type II diabetes.  The role of type II diabetes may simply be the gut.  This has been called metabolic endotoxemia.

LPS links gut to inflammation in Alzheimer's disease

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gut bacteria play role in obesity and metabolic syndrome through inflammation.

Only abstract available here.  Animal study finds that gut bacteria induce diabetes and early antibiotic exposure accelerated this autoimmune activity.  This study also used VSL#3 to attempt to treat but no effect was evident.  

fascinating read on gut inflammation and glucose metabolism.  The gut bacteria implicated her is Akkermansia muciniphila.