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Nathan Goodyear

Inflammatory and Cardiometabolic Risk on Obesity: Role of Environmental Xenoestrogens: ... - 0 views

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    Study finds heavy presence of xenoestrogens in obese Portuguese women, both pre menopause and post menopause.  This study only looked at obese women; it would be nice to have a control of thin women to contrast the plasma and adipose xenoestrogen levels.  The authors found the presence of xenoestrogens in plasma in pre menopause women to be a 10 year predictor of cardiovascular disease risk in these women.  The authors also found increased Xenoestrogen levels to be associated with metabolic dysfunction and inflammation.
Nathan Goodyear

LIGAND STRUCTURE-DEPENDENT ACTIVATION OF ESTROGEN RECEPTOR α/Sp BY ESTROGENS ... - 0 views

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    xenoestrogens are estrogen receptor agonists.  This is a good discussion of there interaction with xenoestrogens and particularly ER alpha.
Nathan Goodyear

Combining xenoestrogens at levels below individual no-observed-effect concentrations dr... - 0 views

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    low levels of environmental toxins add to the effective hormone levels in the body. These are in very low levels of exposure.
Nathan Goodyear

ScienceDirect.com - The Journal of Steroid Biochemistry and Molecular Biology - Estroge... - 0 views

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    low dose xenoestrogen exposure increases prostate growth and future disease through fetal exposure and increased ER alpha expression.
Nathan Goodyear

Exposure of Newborn Male and Female Rats to Environmental Estrogens: Delayed and Sustai... - 0 views

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    xenoestrogen exposure has been shown to increase ER alpha and ER beta in the pituitary.
Nathan Goodyear

Prepubertal exposure to commercial formulation ... [Arch Toxicol. 2010] - PubMed - NCBI - 0 views

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    Glyphosate found to lower Testosterone in rat study.  Glyphosate is a significant xenoestrogen which acts as an endocrine disruptor.
Nathan Goodyear

Male Reproductive Health and Environmental Xenoestrogens - 0 views

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    Good review of xenoestrogens and the impact these endocrine disruptors are having on men.
Nathan Goodyear

Medical Hypothesis: Xenoestrogens As Preventable Causes of Breast Cancer - 0 views

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    good review of some of the literature pointing to the impact of environmental chemicals (xenoestrogens) and cancer
Nathan Goodyear

Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoest... - 0 views

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    article discusses the increased estrogenic effect of the xenoestrogens found in chemical toxins.  This has serious implications in cancer that is estrogenic.
Nathan Goodyear

Reproductive and developmental effects of p... [Crit Rev Toxicol. 2014] - PubMed - NCBI - 0 views

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    phthalates are xenoestrogens that is toxic to male reproductive health.
Nathan Goodyear

EHP - Bisphenol A Exposure during Adulthood Causes Augmentation of Follicular... - 0 views

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    Bisphenol A shown to disrupt ovarian estrogen production from exposure in adults.  The point of this that is important is that BPA, a xenoestrogen, can infact disrupt physiologic hormone production in adults, and contribute to ovarian failure.  BPA, itself, is 1,000 fold weaker than E2, yet it disrupts ovarian function.
Nathan Goodyear

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action - 0 views

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    good review of current knowledge on endocrine disrupting chemicals, more commonly known as xenoestrogens.
Nathan Goodyear

Environmental anti-androgens and male reproductive health: focus on phthalates and test... - 0 views

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    good review of the effect of environmental xenoestrogens and low T in men.
Nathan Goodyear

Glyphosate induces human breast cancer cel... [Food Chem Toxicol. 2013] - PubMed - NCBI - 0 views

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    Shock!  Glyphosphate is a xenoestrogen and promoted growth of breast cancer cells via estrogen receptors. This is only the abstract, but the glyphosate was found to "alter" the ERalpha and ERbeta expression.  These effects were found at low levels existing in the environment.
Nathan Goodyear

Endocrine disruptors: can biological... [Regul Toxicol Pharmacol. 2002] - PubMed - NCBI - 0 views

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    Xenoestrogens disrupt hormones, despite being very weak compared to estradiol.
Nathan Goodyear

Estradiol and Bisphenol A Stimulate Androgen Receptor and Estrogen Receptor Gene Expres... - 0 views

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    Great read on the effects of bisphenol A as an xenoestrogen.  Bisphenol A is a weak estrogen, but it does increase androgen receptor and estrogen receptor alpha transcription.  This is from fetal exposure.
Nathan Goodyear

Serum bisphenol-A concentration and sex hormone levels in men - 0 views

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    Study finds that men exposed to BPA have lower androstenedione and free testosterone compared to those not exposed.  Also of note, SHBG is increased, which is what one would expect with xenoestrogen exposure.
Nathan Goodyear

Annals of Internal Medicine | Are Organic Foods Safer or Healthier Than Conventional Al... - 0 views

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    study claims that organic foods provide no additional nutritional value above non-organic foods.  Problem is, that is not the reason to push organic.  Elimination of xenoestrogens, hormones, and other toxins is.
Nathan Goodyear

Actions of Estrogens and Endocrine Disrupting Chemicals on Human Prostate Stem/Progenit... - 0 views

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    Endocrine Disrupting chemicals, xenoestrogens, alter the hormone receptors very early. Increased estrogenic load with the change in ER increase prostate cancer.
Nathan Goodyear

Human biological monitoring of suspected endocrine-disrupting compounds Fanib... - 0 views

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    Review of xenoestrogens and techniques for evaluation.  Brief discussion of the different EDCs is included, but the majority of the study is to evaluate the different testing techniques.
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