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Nathan Goodyear

Association of serum lead and mercury level with cardiometabolic ri... - PubMed - NCBI - 0 views

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    study finds Pb and Hg associated with increased cardiometabolic risk factors.  Elevated liver enzymes found to be positively associated with serum Pb levels.  Metabolic Syndrome was found to be associated with higher Pb and Hg levels.
Nathan Goodyear

PLOS ONE: Association of Blood Lead (Pb) and Plasma Homocysteine: A Cross Sectional Sur... - 0 views

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    No amount of Pb level exposure is considered safe as levels as low as 3 mcg/dl has been shown to be associated with increased cardiac mortality.  This study found higher Pb levels in men versus women in Pakistan. This correlated with elevated homocysteine levels.  
Nathan Goodyear

Lead acetate may cause erectile dysfunctio... [Cell Biol Toxicol. 2013] - PubMed - NCBI - 0 views

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    In rat model, Pb reduced NO and contributed to ED.  Of interest, arginine masked the effects of Pb on NO synthase and vitamin C reversed it all together.
Nathan Goodyear

Lead Exposure Exacerbates Cardiovascular Risk - 0 views

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    Pb is associated with increased CVD, however, studies are limited and the association is not clear as the exact process by which Pb contributes to CVD is not know.  Oxidative stress and inflammation are proposed as the mechanisms.
Nathan Goodyear

Lead, Genetic Susceptibility, and Risk of Adult Brain Tumors - 0 views

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    this study suggests that Pb exposure, in those with ALAD polymorphism, have an increased risk of meningioma.
Nathan Goodyear

Blood Lead Is a Predictor of Homocysteine Levels in a Population-Based Study of Older A... - 0 views

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    blood lead (Pb)levels associated with elevated homocysteine levels.
Nathan Goodyear

Ameliorative Effect of Vitamin C on Serum Liver Enzymes in Lead-Induced Toxicity in Wis... - 0 views

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    vitamin C reduces liver toxicity with lead (Pb) exposure in Wistar rats.
Nathan Goodyear

Polychlorinated biphenyls, lead, and... [Environ Health Perspect. 2010] - PubMed - NCBI - 0 views

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    PCBs, Pb, and Hg associated with elevated liver enzymes, and non-alcohol fatty liver disease.  
Nathan Goodyear

http://www.scielo.br/pdf/bjmbr/v44n9/1088.pdf - 0 views

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    Nice review on the mechanism of Hg, Pb and gadolinium on the vascular system.  Oxidative stress is increased.  ACE is increased.  Increased vascular reactivity occurs.  Cardiovascular dysfunction results.
Nathan Goodyear

Catcholamine and nitric oxide systems as targets of... [Life Sci. 2000] - PubMed - NCBI - 0 views

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    Pb reduced NO, increased epinephrine and norepinephrine, increased vascular resistance and RAA system which resulted in hypertension.
Nathan Goodyear

http://benthamopen.com/toandroj/articles/V003/6TOANDROJ.pdf - 0 views

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    Case study of Pb induced neurogenic ED.
Nathan Goodyear

Lead-induced dysregulation of superoxide dismuta... [Environ Res. 2005] - PubMed - NCBI - 0 views

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    Pb induces dysfunction of SOD, CAT, and GPX.
Nathan Goodyear

Erectile dysfunction and depression in patients with chronic lead poisoning - Gonulalan... - 0 views

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    Another study links ED to Pb.
Nathan Goodyear

Therapeutic potentials of combined use of DMSA wit... [Biometals. 2008] - PubMed - NCBI - 0 views

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    Study of mice finds DMSA with calcium plus vitamin C chelates/mobilized Pb.
Nathan Goodyear

Kininergic system and arterial hypertensi... [Immunopharmacology. 1999] - PubMed - NCBI - 0 views

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    Animal model finds that Pb induces hypertension at levels similar to general population exposures.
Nathan Goodyear

Lead Exposure and Cardiovascular Disease-A Systematic Review - 0 views

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    review finds evidence dose exist that Pb is associated with a causal relationship with hypertension.
Nathan Goodyear

The inhibitory effects of garlic and Panax ginseng extract standardized with ginsenosid... - 0 views

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    interesting rat study.  EDTA, common chelation therapy of choice for lead (Pb), decreased antioxidant activity and increase lipid per oxidation.  This was inhibited by garlic and RG3.
Nathan Goodyear

Association between Lead and Cadmium and Reproductive Hormones in Peripubertal U.S. Girls - 0 views

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    Study finds higher Pb levels in young girls is associated with delayed puberty onset.  This occurs through an inverse relationship with inhibin B and follicular development.  This relationship was also found with Cadmium.  Both of these heavy metals are toxic to the ovaries.
Nathan Goodyear

Chronic lead exposure may be associated with erect... [J Sex Med. 2007] - PubMed - NCBI - 0 views

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    chronic lead exposure associated with ED in men.  As lead is a contributor to CVD, logically, this is not a surprise.
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