JAMA Network | JAMA | Menopausal Hormone Therapy and Health Outcomes During the Interve... - 0 views
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Nathan Goodyear on 02 Oct 13This study cannot make the conclusion AT ALL. They claim to say hormones should not be used to prevent chronic disease. Yet, the study they use to support this statement, the WHI, did not look at hormones. The WHI looked at premarin and medroxyprogesterone acetate, a progestin. They are not the hormones the body makes. Second, the WHI looked at women that were 6 years postmenopausal, on average, and then they added in bad drugs, disguised as hormone like, and then were dosed high. If one desires to truly make a statement of prevention, one needs to pre-empt testing and therapy before disease. Additionally, the study needs to match the hormones needed at the right physiologic level in the right balance. One must also ensure proper hormone metabolism and know hormone receptor status. This study does non of the above and the conclusion of this study is irrelevant. In fact, I think the authors of this study have undergone scientific malpractice in their conclusions.