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Contents contributed and discussions participated by Nathan Goodyear

Nathan Goodyear

Cases Journal | Full text | Sudden elevation of liver enzymes in a 64-year-old patient:... - 0 views

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    case study of elevated liver enzymes induced by antibiotics.
Nathan Goodyear

Acute cholestatic hepatitis caused by amoxicillin/clavulanate - 0 views

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    acute hepatitis by augmentin
Nathan Goodyear

A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage - 0 views

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    amoxil induced liver injury manifest with elevated liver enzymes.
Nathan Goodyear

Frontiers | Sarcopenia and Androgens: A Link between Pathology and Treatment | Endocrin... - 0 views

  • sarcopenia induces a change in the proportion of skeletal muscle fibers, inducing a shift from type II (fast) to type I (slow) fibers as well as preferential loss of type II fibers
  • testosterone stimulates protein synthesis by both a short-term mechanism-rapid activation of pre-existing components of the translational apparatus- and a long-term mechanism-increase in cell or tissue capacity at the protein synthesis level leading to increase in ribosome quantity
  • testosterone induces an increase in cross-sectional area (CSA) in type I and II muscle fibers and in myonuclear quantity, indicating that testosterone exerts more of a hypertrophic than a hyperplasic effect on skeletal muscle
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    good discussion of sarcopenia.
Nathan Goodyear

American College of Cardiology Foundation | Article - 0 views

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    Poster found that aged garlic extract plus CoQ10 slowed coronary artery calcification and decreased Lp-PLA2 compared to placebo.
Nathan Goodyear

JAMA Network | JAMA Internal Medicine | Lipoprotein-Associated Phospholipase A2, High-S... - 0 views

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    increased LP-PLA2 and hsCRP are associated with increased risk of ischemic stroke.
Nathan Goodyear

http://circ.ahajournals.org/content/109/7/837.full.pdf - 0 views

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    LP-PLA2 (Lipoprotein-Associated Phospholipase A2) with hs-CRP are associated with increased CHD events in those with low LDL-C.
Nathan Goodyear

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cel... - 0 views

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    Testosterone increases muscle satellite cells in men.
Nathan Goodyear

http://www.uclouvain.be/cps/ucl/doc/ir-ldri/images/BINDELS2013IJBCLB.pdf - 0 views

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    gut microflora and its impact on muscle loss/muscle growth.  Not just for lean versus fat evaluation.
Nathan Goodyear

Effects of Age and Sedentary Lifestyle on Skeletal Muscle NF-κB Signaling in Men - 0 views

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    Aging and sedentary lifestyle associated with muscle loss through NF-KappaB activation.
Nathan Goodyear

Regulation of muscle mass by growth hormone and IGF-I - 0 views

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    good review of GH and IGF-1 impact on muscle growth/muscle loss.
Nathan Goodyear

Gonadotropin treatment restores in vitro interleukin-1β and tumour necrosis f... - 0 views

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    Inverse relationship between Testosterone and LPS, IL-1beta, and TNF-alpha.
Nathan Goodyear

Association of Hashimoto's thyroiditis with thyroid cancer - 0 views

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    This prospective study finds association with Thyroid cancer with TgAb and not TPO in those with thyroid nodules.
Nathan Goodyear

Is Hashimoto's thyroiditis a risk factor for papillary thyroid cancer? - 0 views

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    This one size treats all approach that medicine takes in its recommendations to cancer evaluation is BS (forgive my french).  Women with Hashimoto's disease are at increased risk of Papillary Thyroid cancer risk (30%) compared to those without.  
Nathan Goodyear

Cancer risk in patients with Hashimoto's thyroiditis: a nationwide cohort study - 0 views

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    Hashimoto's thyroid disease is associated with increased cancer in women: particularly in this study--Thyroid and colorectal.
Nathan Goodyear

High prevalence of Hashimoto's thyroiditis in patients with polycystic ovary syndrome: ... - 0 views

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    Hashimoto's thyroid disease associated with PCOS in women; this was found to be associated with an increased Estradiol:Progesterone ratio.  
Nathan Goodyear

Is serum sex hormone-binding globulin a dominant risk factor for metabolic syndrome? - ... - 0 views

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    Nice study of Chinese men, only abstract available, finds that serum total Testosterone and SHBG were inversely associated with metabolic syndrome in men.  SHBG association was the strongest and TT the weakest.  Free Testosterone had no association in this study.
Nathan Goodyear

Urolithiasis is associated with low serum testosterone levels in men | Otunctemur | Arc... - 0 views

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    low Testosterone is associated with kidney stones in men through increased Metabolic Syndrome.  Better stated, low T is associated with metabolic syndrome and this metabolic dysfunction increased the findings of kidney stones in men.
Nathan Goodyear

Fundamental Aspects of Hypogonadism in the Aging Male - 0 views

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    good discussion of low T effect on a man's metabolism: particularly muscle mass.
Nathan Goodyear

Measurement of fasting salivary insulin and its relationship with serum insulin in chil... - 0 views

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    Salivary insulin correlates well with serum insulin.
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