Delayed Neuroendocrine Sexual Maturation in Female Rats After a Very Low Dose of Bisphe... - 0 views
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Nathan Goodyear on 18 May 16low dose of BPA in rat model finds delayed sexual maturation.
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Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secret... - 0 views
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only abstract available here. Mouse model finds possible explanation for low Testosterone and diabetes link. Actually, the link is between the metabolite DHT and the AR. The activity of AR from DHT binding induces beta cell insulin secretion in the presence of glucose. This is dependent on glucagon-like peptide 1 receptor activation also, which AR activation by DHT does in fact do.
Fructose-induced leptin resistance exacerbates weight gain in response to subsequent hi... - 0 views
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Another rat model finds that high fructose intake causes leptin resistance and worsens leptin resistance.
http://journals.cambridge.org/download.php?file=%2FBJN%2FBJN106_03%2FS000711451100033Xa... - 0 views
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elimination of sugar, fructose in rat model found to reverse leptin resistance.
Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and lep... - 0 views
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exercise found to improve central insulin and leptin resistance in obese animal model. The mechanism was via a decrease in inflammation through decrease in PTP1B protein transcription.
Exercise protects against high-fat diet-induced hypothalamic inflammation. - PubMed - NCBI - 0 views
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regular treadmill exercise reduced hypothalamic inflammation, improved insulin resistance, improved leptin resistance, improved glucose tolerance, and decreased microglia activation in high-fat animal model.
High-fructose diet leads to visceral adiposity and hypothalamic leptin resistance in ma... - 0 views
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high fructose diet for just 9 weeks, > 60% liquid fructose, in rat model found to increase visceral adiposity, triglycerides, and lead to leptin resistance.
Saccharomyces boulardii Administration Changes Gut Microbiota and Reduces Hepatic Steat... - 0 views
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Saccharomyces boulardii found to reduce weight, fat mass, fatty liver, and inflammation in mice diabetes and obesity models.
Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglycerid... - 0 views
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curcumin found to reduce leptin resistance and insulin resistance in fructose-induced hypertriglyceridiemia in rat model.
Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Die... - 0 views
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NAD found to be useful in the treatment of diabetes in animal model. The positive effect is through increased Sirtuin activity
Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3 | ... - 0 views
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NAD in the form of nicotinamide riboside found to be effective in treating mitochondrial myopathy in animal model.
Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in gui... - 0 views
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animal model finds that glutathione depletion increases hyperactivity of bronchioles. Early exposure to glutathione ethyl ester, a precursor to glutathione, blunted the airway hyperactivity.
Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostat... - 0 views
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In rat model, Estradiol shown to increase inflammation in lateral lobes of the prostate. Androgens, Testosterone > DHT, shown to inhibit this inflammatory response.
Dehydroepiandrosterone Modulates Nuclear Factor-κB Activation in Hippocampus ... - 0 views
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Fascinating article: DHEA found to decrease NF-KappaB activity in the hippocampus region of the brain. This has implications in protecting the brain. In this study, the implication was reduction in inflammation in the hippocampus region in diabetic rat model.
Web of Knowledge [v.5.3] - Web of Science - 0 views
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animal model: showed that DHEA treatment resulted in increased adiponectin secretion from fat cells. This occurred with an associated increase in PPAR-gamma receptors. The suggestion is that DHEA through PPAR-gamma increased fat cell production and secretion of adiponectin.
Inhibitory Effect of Progesterone on Inflammatory Factors after Experimental Traumatic ... - 0 views
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Now, this is in a rat TBI model; but progesterone was shown to reduce the inflammatory response post TBI. Particularily, through NF-kappa B inhibition.
Acute changes in 5-HT metabolism after S-adeno... [Gen Pharmacol. 1989] - PubMed - NCBI - 0 views
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SAMe increased hippocampal serotonin levels by 300% in rat brain model. Methylation is known to play a major role in serotonin, dopamine, and norepinephrine.
S-adenosylmethionine reduces the progress of... [Neurobiol Aging. 2012] - PubMed - NCBI - 0 views
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SAMe helps to correct disordered homocysteine metabolism due to B- vitamin deficiency found in Alzheimer's disease. SAMe show to reduce amyloid production, improve memory, decrease Tau, and reduced plaque formation. Now, this was in a mice model, but SAMe as a methyl donor can benefit clients with dementia with minimal side effects.
Testosterone therapy in men with untreated prostate c... [J Urol. 2011] - PubMed - NCBI - 0 views
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testosterone therapy in men with untreated prostate cancer was found to not be associated with cancer progression. These men were followed over an average 2.5 years. They concluded that, "these results are consistent with the saturation model i.e.. maximal prostate cancer growth is achieved at low androgen concentrations.
Progesterone and allopregnanolone reduce inflamma... [Exp Neurol. 2004] - PubMed - NCBI - 0 views
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progesterone and allopregnanolone shown to reduce IL-1beta and TNF-alpha in TBI rat model.
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