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Nathan Goodyear

Dietary composition in the treatment of polycystic ovary syndrome: a systematic review ... - 0 views

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    Weight loss is the best positive effect for women with PCOS.  Higher fat and protein, with a lower carb diet benefited women with PCOS.  A low Glycemic index plan benefited women with PCOS.  
Nathan Goodyear

Substituting whole grains for refined grains in a 6-wk randomized trial has a modest ef... - 0 views

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    small study finds diet rich in whole grains compared to refined grains improves gut bacteria balance and immune system.  Maybe the key to optimal gut health is the diet?
Nathan Goodyear

Steam cooking significantly improves in vitro bile acid binding of collard greens, kale... - 0 views

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    steamed veggies aid acid function.
Nathan Goodyear

Dietary agents that target gastrointestinal and hepatic handling of bile acids and chol... - 0 views

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    good review of foods to increase in diet when gall bladder has been removed or gall bladder dysfunction is present.
Nathan Goodyear

Dietary factors and luteal phase deficiency in healthy eumenorrheic women - 0 views

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    great read and review of diet and hormones in cycling women.
Nathan Goodyear

Effect of low-fat diet on female sex hormone levels. - PubMed - NCBI - 0 views

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    low fat diet drops estrogen levels precipitously in women.  It also dropped Testosterone levels.
Nathan Goodyear

http://jap.physiology.org/content/jap/82/1/49.full.pdf - 0 views

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    To much protein intake can be a bad thing.  This study found that high protein intake and high protein/carbohydrate intake lowered basal Testosterone levels.
Nathan Goodyear

The Mediterranean Diet and ADHD in Children and Adolescents | Articles | Pediatrics - 0 views

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    Is ADHD simply a reflection of poor diet?
Nathan Goodyear

Diet and Risk of Colorectal Cancer Subtypes Classified by F nucleatum | Colorectal Canc... - 0 views

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    Study finds Diet effect colon cancer risk through gut bacteria. Diet higher in fiber and whole grains found to have lower risk of F nucleatum + colon cancer.
Nathan Goodyear

Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity - 0 views

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    New study how the Western diet acts like a drug in the body.
Nathan Goodyear

Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic... - 0 views

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    new animal study finds that high fiber diet intake increases gut flora SCFA production that reduces inflammation in gout
Nathan Goodyear

An adaptive response to uncertainty can lead to weight gain during dieting attempts - 0 views

  • dieting attempts cause weight gain via providing (misleading) information about the environment to the subconscious systems that control body mass
  • Our model predicts that energy reserves should respond to repeated attempts to diet by weight cycling and becoming greater from one cycle to the next
  • the very conditions that cause weight gain initially—a glut of food—causes further weight gain once cyclical dieting begins
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  • There is evidence that among weight cycling, people those who switch between dieting and binge-eating more frequently gain more weight
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    yo-yo dieting leads to weight gain, in part, due to increase food intake in between the calorie restriction phases.  The calorie restriction suppresses metabolic rate and results in muscle loss; both of which contribute to the rebound weight gain seen by so many.
Nathan Goodyear

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Re... - 0 views

  • Long-term DPs play a large role in determining the selective environment that the gut microbiota faces, ultimately influencing the composition and diversity of taxa maintained within the gut microbial community
  • Americans consuming unrestricted diets maintained less diverse fecal microbiota than those of individuals adhering to a plant-rich diet with restricted caloric intake
  • Experiments in mice have shown that multigenerational exposure to a Western diet poor in “microbiota-accessible carbohydrates” can lead to extirpation of specific bacterial lineages
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    Diet is the key to gut microbe diversity.  Gut microbes are key to maintaining optimal cellular metabolism.  Nutrition can be a prescription for improving and reprogramming gut bacteria.
Nathan Goodyear

Dietary carbohydrate restriction as the first approach in diabetes management: Critical... - 0 views

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    ketogenic diet should be first step in diabetes treatment, according to review.
Nathan Goodyear

Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tis... - 0 views

  • SCFAs play a dual role both as substrates for metabolism and as signaling molecules
  • SCFAs can be either directly converted (acetate) or oxidized (propionate and butyrate) to acetyl-Co
  • Here we demonstrate that microbial colonization regulates global histone acetylation and methylation in multiple host tissues in a diet-dependent manner
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  • complex functional interactions between diet, gut microbiota, and host health.
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    diet changes gut microbiota, which changes genetic expression--it is called epigenetics.  This is an animal study.
Nathan Goodyear

PLOS ONE: The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice wit... - 0 views

  • This finding strongly supports the efficacy of the KD and HBO2T as therapies to inhibit tumor progression and prolong survival in animals with metastatic cancer.
  • We found that the KD fed ad libitum significantly increased mean survival time in mice with metastatic cancer
  • Ketogenic diets are also known to have an appetite suppressing effect which may contribute to body weight loss
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  • the ketogenic diet may inhibit cancer progression in part by indirect dietary energy restriction
  • KD with HBO2T. Combining these therapies nearly doubled survival time in mice with metastatic cancer,
  • low carbohydrate or ketogenic diets promote weight loss in overweight individuals, they are also known to spare muscle wasting during conditions of energy restriction and starvation
  • dietary-induced therapeutic ketosis in a cancer patient would prevent muscle wasting similarly as it does with athletes undergoing intense exercise
  • when given as an adjuvant treatment to advanced cancer patients, the KD improves quality of life and enhances the efficacy of chemotherapy treatment in the clinic
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    mouse study finds that ketogenic diet plus hyperbaric O2 treatment prolongs survival.
Nathan Goodyear

Ketone bodies as a fuel for the brain during starvation - Owen - 2005 - Biochemistry an... - 0 views

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    Ketones, acetoacetate, beta-hydroxybutyrate, and acetone, feed the brain independent of glucose.
Nathan Goodyear

Ketogenic Diet - Nutrition and Traumatic Brain Injury - NCBI Bookshelf - 0 views

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    good review of the impact of ketones on TBI.  The authors conclude that precursors to ketones may be the right approach to treatment.  This would be MCT's and ketones.
Nathan Goodyear

The Ketogenic Diet and Sport: A Possible Marriage? : Exercise and Sport Sciences Reviews - 0 views

  • It is important to note that, although the blood level of glucose drops, it still remains at a physiological level (23), which is maintained through gluconeogenesis involving glucogenic amino acids and also glycerol released from triglycerides
  • “physiological ketosis” where KB levels may rise to 7 to 8 mmol L-1 (but without any pH change). In “pathological diabetic ketoacidosis,” on the other hand, ketonemia can exceed 20 mmol L-1 and also cause lowering of blood pH
  • in the initial phase of KD, about 16% of glucose comes from glycerol (released from triglyceride hydrolysis) and the bulk (60–65 g) from proteins via gluconeogenesis (proteins may be of either dietary or endogenous origin
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  • the protein supply consumed during a KD “preserves,” as demonstrated, lean body mass
  • The importance of glycerol as a glucose source increases progressively during ketosis; in fact, glycerol passes from supplying 16% of total glucose to an average of 60% after many days (>7 d) of complete fasting (from 38% in lean individual to 79% in the obese).
  • The possible reasons for the effectiveness of KD for weight loss may be listed as follows, in order of evidence, strongest first:

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    1. Appetite reduction: protein satiety, effects on appetite-related hormones such as ghrelin, and possibly a sort of direct appetite-blocking effect of KB

    2. Reduced lipogenesis and increased fat oxidation

    3. A reduction in respiratory quotient may indicate a greater metabolic efficiency in fat oxidation

    4. A thermic effect of proteins and increased energy usage by gluconeogenesis

  • all data regarding biochemical and molecular mechanisms suggest that it is very difficult to increase muscle mass during a KD; use of which really should be limited to the few days immediately before competition in bodybuilding.
  • a long-term KD can interfere with some muscle hypertrophy mechanisms and this could be counterproductive if the aim of the athlete is to gain muscle mass
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    Great read on the ketogenic  and its application to sports/training...
Nathan Goodyear

Anticonvulsant Mechanisms of the Ketogenic Diet - Bough - 2007 - Epilepsia - Wiley Onli... - 0 views

  • The ketogenic diet (KD) is a high-fat, low-protein, low-carbohydrate diet that has been employed as a treatment for medically refractory epilepsy for 86 years
  • The hallmark feature of KD treatment is the production of ketone bodies by the liver
  • almost any diet that produces ketonemia and/or diminished blood glucose levels can induce an anticonvulsant effect.
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    ketogenic diet reduces seizures.  Proposed mechanisms: reduced insulin, reduced ROS, reduces oxidative stress, reduced inflammation, increased GABA/Gluatamate ratio.  In the end, it reduces inflammation and increases mitochondrial efficiency.
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