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Nathan Goodyear

Nebulized Glutathione Induces Bronchoconstriction in Patients with Mild Asthma (ATS Jou... - 0 views

www.atsjournals.org/...ajrccm.156.2.9611001

asthma glutathione GSH GSH peroxidase

shared by Nathan Goodyear on 07 Jul 16 - No Cached
  • Nathan Goodyear on 07 Jul 16
     
    Study finds that nebulizer glutathione in mild asthma induces bronchoconstriction.  This despite the knowledge that glutathione peroxidase activity is known to be depressed in those with asthma.  The severity of the asthma of the individuals included in this study might explain the finding.
Nathan Goodyear

Probiotics for the treatment of a... [Ann Allergy Asthma Immunol. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19119700

probiotics allergy asthma

shared by Nathan Goodyear on 19 Feb 13 - No Cached
  • Nathan Goodyear on 19 Feb 13
     
    A meta analysis of 12 randomized controlled trials found that 9 found improvement in allergies and asthma with probiotics.   A lot of studies have looked at probiotics and the prevention of allergies and asthma, but this meta analysis shows probiotics should be used as a part of therapy.
Nathan Goodyear

Effectiveness of influenza vaccine for the prevention of asthma exacerbations - 0 views

www.ncbi.nlm.nih.gov/...PMC1720017

flu influenza flu vaccine asthma pediatrics vaccine vaccinations

shared by Nathan Goodyear on 10 May 16 - No Cached
  • Nathan Goodyear on 10 May 16
     
    flu vaccine does not prevent asthma exacerbations in those with asthma.
Nathan Goodyear

Glutathione Redox Regulates Airway Hyperresponsiveness and Airway Inflammation in Mice ... - 0 views

www.atsjournals.org/...rcmb.2006-0423OC

glutathione asthma inflammation

shared by Nathan Goodyear on 07 Jul 16 - No Cached
  • γ-GCE reduced levels of IL-4, IL-5, IL-10, and the chemokines eotaxin and RANTES (regulated on activation, normal T cell expressed and secreted) in bronchoalveolar lavage fluid, whereas it enhanced the production of IL-12 and IFN-γ.
  • γ-GCE suppressed eosinophils infiltration
  • γ-GCE directly inhibited chemokine-induced eosinophil chemotaxis
  • ...10 more annotations...
  • these findings suggest that changing glutathione redox balance, increase in GSH level, and the GSH/GSSG ratio by γ-GCE, ameliorate bronchial asthma by altering the Th1/Th2 imbalance through IL-12 production from APC and suppressing chemokine production and eosinophil migration itself.
  • Bronchial asthma is a typical helper T cell type 2 (Th2) disease
  • Through the release of Th2 cytokines, such as IL-4, IL-5, and IL-13, orchestrate the recruitment and activation of the primary effector cells of the allergic response: the mast cells and the eosinophils
  • Glutathione is the most abundant nonprotein sulfhydryl compound in almost all cells. This tripeptide plays a significant role in many biological processes. It also constitutes the first line of the cellular defense mechanism against oxidative injury along with SOD, ascorbate, vitamin E, and catalase, and is the major intracellular redox buffer in ubiquitous cell types
  • We have shown that glutathione redox status, namely the balance between intracellular reduced (GSH) and oxidized (GSSG) glutathione, in murine antigen-presenting cells (APC) plays a central role in determining which of the reductive and oxidative APC predominate during immune status, and the balance between reductive and oxidative APC regulates Th1/Th2 balance through production of IL-12
  • we have also shown that exposure of human alveolar macrophages to the Th1 cytokine IFN-γ or the Th2 cytokine IL-4 either increases or decreases the GSH/GSSG ratio, respectively, which regulates Th1/Th2 balance through IL-12 production
  • the ability to generate a Th1 or Th2 type response has turned out to depend not only on T cells but also on the intracellular glutathione redox status of APC
  • Th1 cytokine IFN-γ and Th2 cytokine IL-4 increases and decreases the GSH/GSSG ratio, respectively, and that this ratio influences LPS-induced IL-12 production from alveolar macrophages
  • the ability to generate a Th1 or Th2 response is dependent on glutathione redox status of APC
  • administration of γ-GCE elevates GSH level and GSH/GSSG ratio in the lung, and ameliorates AHR and eosinophilic airway inflammation by altering the Th1/Th2 balance and suppressing chemokine production and eosinophil migration in a mouse asthma model
  • Nathan Goodyear on 07 Jul 16
     
    glutathione redox reaction plays an important role in the ability to balance Th1 and Th2 and thus disease potential i.e. asthma as this study example.  
SEO Husain

Asthma information | Asthma Homeopathic Treatment - Dr. Batra's - 0 views

www.drbatras.com/asthma

asthma bronchial asthmatic bronchitis alternative medicine homeopathy homeopathic treatment remedy cure asthama wheezing wheeze breathlessness inhalers hypersensitivity allergy

shared by SEO Husain on 22 Aug 12 - No Cached
  • SEO Husain on 22 Aug 12
     
    Asthma makes breathing difficult for more than 300 million people worldwide according to the WHO. Treat your bronchial asthma/ breathlessness/ wheezing/ respiratory allergy with Homeopathy at Dr. Batra's
Nathan Goodyear

AACI | Full text | The role of Probiotics in allergic diseases - 0 views

www.aacijournal.com/5

probiotics asthma allergic rhinitis allergies

shared by Nathan Goodyear on 20 Feb 13 - No Cached
  • Nathan Goodyear on 20 Feb 13
     
    studies of probiotics in the treatment of asthma and allergic rhinitis are mixed.  Studies do strongly suggest benefit in therapy for allergic rhinitis, but this study found no benefit with regards to asthma in its review of the literature.
Nathan Goodyear

L-Carnitine Improves the Asthma Control in Children with Moderate Persistent Asthma - 0 views

www.hindawi.com/...509730

asthma L-carnitine children

shared by Nathan Goodyear on 31 Jul 12 - No Cached
  • Nathan Goodyear on 31 Jul 12
     
    L-carnitine is effective as adjunct in the treatment of moderate persistent asthma.
Nathan Goodyear

Magnesium significantly improves severe acute asthma in children. - 0 views

www.greenmedinfo.com/...s-severe-acute-asthma-children

magnesium IV intravenous asthma children

shared by Nathan Goodyear on 12 Jan 14 - No Cached
  • Nathan Goodyear on 12 Jan 14
     
    IV magnesium shown to provide benefit in children with moderate/severe asthma.
Nathan Goodyear

Androgens are bronchoactive drugs that act by relaxing airway smooth muscle and prevent... - 0 views

joe.endocrinology-journals.org/...1.abstract

low T Testosterone metabolites asthma dihydrotestosterone

shared by Nathan Goodyear on 09 Jul 14 - No Cached
  • Nathan Goodyear on 09 Jul 14
     
    Androgens relax smooth muscles of airways in men with asthma.  The metabolite 5beta-DHT was the most potent in this action.  This has implications in men with low T and asthma.  
Nathan Goodyear

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in school... - 0 views

ajcn.nutrition.org/...1255.long

vitamin d influenza flu vitamin d3 asthma

shared by Nathan Goodyear on 20 Sep 17 - No Cached
  • Nathan Goodyear on 20 Sep 17
     
    Nice study from a few years ago found that a low dose vitamin D3 (1200 IU) significantly reduced the relative risk of the flu in school age children.  Also of note, a significant reduction in asthma attacks in those children with asthma were significantly reduced in the vitamin D3 treated group.  One interesting thing about this study was that they did not check prior or during the study if vitamin D deficiency was even present.  This study was conducted in Japan
Nathan Goodyear

Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-B... - 0 views

www.mayoclinicproceedings.org/...abstract

oophorectomy menopause chronic disease of aging women hormones

shared by Nathan Goodyear on 04 Oct 16 - No Cached
  • Nathan Goodyear on 04 Oct 16
     
    For most women, the practice of pre-menopausal, preventative removal of ovaries should be no more.  Evidence does not support a reduction in ovarian cancer; but, it does support an increased risk of depression, hyper lipidemia, cardiac arrhythmia, CAD, arthritis, asthma, COPD, and asthma.
Nathan Goodyear

Magnesium supplementation improves objective and subjective symptoms - 0 views

www.greenmedinfo.com/...and-subjective-symptoms-asthma

magnesium asthma

shared by Nathan Goodyear on 12 Jan 14 - No Cached
  • Nathan Goodyear on 12 Jan 14
     
    Oral magnesium benefits adults with asthma.  Both subjective and objective, FEV1 and PEFR, measures improved
Nathan Goodyear

Effects of vitamin D on immune disorders with special regard to asthma, COPD and autoim... - 0 views

www.expert-reviews.com/...ers.12.57

vitamin d vitamin autoimmune diseases asthma COPD

shared by Nathan Goodyear on 12 Aug 13 - No Cached
  • Nathan Goodyear on 12 Aug 13
     
    Vitamin D is an important immunomodulator.  Vitamin D shown to have benefit in Th1 and Th2 mediated disease states. Asthma and COPD benefit and other Th1 mediated diseases, such as MS, type 1 Diabetes, RA...
Nathan Goodyear

Salivary cortisol monitoring: de... [Allergy Asthma Proc. 2012 Jul-Aug] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22856637

saliva salivary cortisol testing hormone hormones

shared by Nathan Goodyear on 04 Jan 13 - No Cached
  • Nathan Goodyear on 04 Jan 13
     
    This study found salivary cortisol testing is a better technique for children, in evaluating HPA axis function in children with asthma.
Nathan Goodyear

Estrogen Receptor β: Expression Profile and Possible Anti-Inflammatory Role i... - 0 views

jpet.aspetjournals.org/...83.full

ER-beta estrogen hormone hormones receptor inflammation anti-inflammatory asthma disease

shared by Nathan Goodyear on 11 Oct 12 - No Cached
  • Nathan Goodyear on 11 Oct 12
     
    ER-beta, known to have anti-inflammatory effects, not shown to have positive effect on asthma.
Jadibuti jadibuti.net

Home Remedies for Cough - 0 views

jadibuti.net/home-remedies-cough

Cough

shared by Jadibuti jadibuti.net on 29 May 16 - No Cached
  • Jadibuti jadibuti.net on 29 May 16
     
    Coughing is common health problem and it may arise due to blockage or irritant in your throat or upper respiratory tract. Coughing can also be due to a viral infection, common cold, flu, and smoking or health problems such as asthma, ...
  • Jadibuti jadibuti.net on 29 May 16
     
    Coughing is common health problem and it may arise due to blockage or irritant in your throat or upper respiratory tract. Coughing can also be due to a viral infection, common cold, flu, and smoking or health problems such as asthma, ...
Nathan Goodyear

Role of certain trace minerals in oxidative stress, inflammation, CD4/CD8 lymphocyte ra... - 0 views

acb.sagepub.com/...344.abstract

asthma selenium zinc copper glutathione hs-CRP TBARS FEV1 FVC catalase inflammation minerals

shared by Nathan Goodyear on 07 Jul 16 - No Cached
  • Nathan Goodyear on 07 Jul 16
     
    Asthma associated with low selenium, low zinc, high copper, low glutathione peroxidase, glutathione reductase, and catalase activity; in contrast, increased hs-CRP, and TBARS was  noted.  Interesting that FEV1 and FVC positively correlated with Se levels.
Nathan Goodyear

Curcumin attenuates the development of allergic airway inflammation and hyper-responsiv... - 0 views

www.greenmedinfo.com/...ation-and-hyper-responsiveness

curcumin inflammtion airway allergy allergies NF-KappaB asthma

shared by Nathan Goodyear on 19 Jan 12 - No Cached
  • Nathan Goodyear on 19 Jan 12
     
    curcumin shown to inhibit allergic airway inflammation, through NF-kappaB inhibition.  This has implications in asthma flares.
Nathan Goodyear

Green tea (Camelia sinensis) mediated suppre... [Scand J Immunol. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22670643

green tea extract EGCG asthma

shared by Nathan Goodyear on 12 Jan 14 - No Cached
  • Nathan Goodyear on 12 Jan 14
     
    Green tea extract, EGCG, found to decrease IgE production.  This would have benefit in asthma.
Nathan Goodyear

Fish oil compares favorably to montelukast Singular in reducing the - 0 views

www.greenmedinfo.com/...cing-severity-exercise-induced

fish oil fish oil n-3 omega 3 omega-3 asthma

shared by Nathan Goodyear on 12 Jan 14 - No Cached
  • Nathan Goodyear on 12 Jan 14
     
    n-3 equivalent to singulair in the treatment of asthma.
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