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Nathan Goodyear

Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and lep... - 0 views

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    exercise found to improve central insulin and leptin resistance in obese animal model.  The mechanism was via a decrease in inflammation through decrease in PTP1B protein transcription.
Nathan Goodyear

Neuronal protein tyrosine phosphatase 1B deficienc... [Mol Cell Biol. 2009] - PubMed re... - 0 views

  • the mechanism by which PTP1B regulates adiposity and leptin sensitivity likely involves the coordinated regulation of AMPK in hypothalamus and peripheral tissues.
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    improved leptin sensitivity leads to weight loss and increased energy expenditure
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