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Nathan Goodyear

Neurologic Symptoms in Licensed Private Pesticide Applicators in the Agricultural Healt... - 0 views

www.ncbi.nlm.nih.gov/...PMC1257649

pesticides neurologic dysfunction disease organophosphates organochlorides fungicides

shared by Nathan Goodyear on 01 Jul 11 - No Cached
  • These results suggest that self-reported neurologic symptoms are associated with cumulative exposure to moderate levels of fumigants and organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning.
  • Nathan Goodyear on 01 Jul 11
     
    pesticides and it's neurologic consequences
Nathan Goodyear

Association of Pesticide Exposure with Neurologic Dysfunction and Disease - 0 views

www.ncbi.nlm.nih.gov/...PMC1247187

pesticide neurologic dysfunction organophospahtes organochlorides fungicides fumigants

shared by Nathan Goodyear on 01 Jul 11 - No Cached
  • Nathan Goodyear on 01 Jul 11
     
    pesticide exposure contributes to neurologic dysfunction
jpsonal

Advanced Neurology & Superspeciality Hospital Jaipur| THE BRAIN TOWER - 0 views

thebraintower.com/treatments.html

Advanced Neurology Hospital treatment Jaipur Neurosurgery In physiotherapy paralysis

shared by jpsonal on 27 Jan 15 - No Cached
  • jpsonal on 27 Jan 15
     
    Advanced Neurology & Superspeciality Hospital is an exclusive neurosciences superspeciality hospital of Jaipur,Rajasthan,commonly known by the name of THE BRAIN TOWER. Dr.Sunit shah, man behind brain tower provides treatment of Neurology,physiotherapy,paralysis & Neurosurgery
spineneuro

Revolutionizing Neurological Care: A Look at Dr. Vipul Gupta's Innovative Techniques - 0 views

www.briefingwire.com/...l-guptas-innovative-techniques

Dr. Vipul Gupta best interventional neurologist in Delhi India Radiologist at Artemis Hospital Gurgaon

shared by spineneuro on 01 May 23 - No Cached
  • spineneuro on 01 May 23
     
    The best interventional neurologist in Delhi India is one of India's most experienced neuro-interventional surgeons and interventional neuroradiologists. Dr. Vipul Gupta India has a patient-centered treatment philosophy, in which his patients come first. He has trained to develop the highest degree of specialization in interventional neurology in India.
spineneuro

From Darkness to Hope: Dr. Vipul Gupta's Extraordinary Contributions to Neurological Ca... - 0 views

www.briefingwire.com/...-to-neurological-care-in-delhi

Dr. Vipul Gupta Best interventional neurologist in Delhi India

shared by spineneuro on 21 Jun 23 - No Cached
  • spineneuro on 21 Jun 23
     
    Dr. Vipul Gupta also researches new therapies, such as stem cell therapy for Cerebrovascular accidents. You can rely on the Best interventional neurologist in Delhi India for comprehensive care, from lifesaving Cerebrovascular accident and aortic care from you from diagnosis through recovery, ensuring you maintain great neurological health.
spineneuro

Journey to Healing: Unraveling the Excellence of Dr. Paresh Doshi, Top Neurosurgeon in ... - 0 views

www.briefingwire.com/...shi-top-neurosurgeon-in-mumbai

Dr. Paresh Doshi Top neurosurgeon at Jaslok Hospital Mumbai

shared by spineneuro on 16 Nov 23 - No Cached
  • spineneuro on 16 Nov 23
     
    Top neurosurgeon at Jaslok Hospital Mumbai offers seamless patient services of world-class quality, catering to the unique needs and requirements of international patients, particularly those with special needs. Recognizing that international patients seeking neurology treatment in India have distinct needs, Dr. Paresh Doshi India ensures the provision of highly specialized neurology treatment.
spineneuro

Best Gamma Knife Neurosurgeon in Delhi Offers The Best in Neurology - Spine and Neuro H... - 0 views

spineandneurosurgeryhospitalindia.wordpress.com/...i-offers-the-best-in-neurology

gamma knife surgery gamma knife radiosurgery Dr. Sandeep Vaishya best gamma knife neurosurgeon in Delhi

shared by spineneuro on 25 Feb 22 - No Cached
  • spineneuro on 25 Feb 22
     
    The gamma knife surgery with the best gamma knife neurosurgeon in Delhi is very lower about 30 to 70 percent less expensive when compared to the cost of the surgery in the developed nations. According to a recent survey, patients can save up to 85% of the costs when they visit India for their neurological treatments. Dr. Sandeep Vaishya Email id: dr.sandeepvaishya@neurospinehospital.com Call:- +91-9325887033
Nathan Goodyear

LRRK2 G2019S Impairs Chaperone-Mediated Autophagy in Neurons (S13.003) -- Kuo et al. 80... - 0 views

www.neurology.org/...S13.003

Parkinsons disease neurology Lewy Bodies Chaperone-mediated autophagy

shared by Nathan Goodyear on 01 Jun 13 - No Cached
  • Nathan Goodyear on 01 Jun 13
     
    impaired auto destruction process leads to the Lewy bodies found in Parkinson's disease.
Nathan Goodyear

Long-term persistence of vaccine-derived alu... [J Inorg Biochem. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19748679

aluminum vaccine vaccinations neurologic brain cognition

shared by Nathan Goodyear on 09 Oct 13 - No Cached
  • Nathan Goodyear on 09 Oct 13
     
    Migration and long-term neurologic dysfunction as a result of aluminum hydroxide.
Nathan Goodyear

New Study Links Aluminum Adjuvants in Vaccines with Neurological Disorders | Health Imp... - 0 views

healthimpactnews.com/...es-with-neurological-disorders

aluminum vaccines vaccinations brain neurology inflammation Macrophagic myofasciitis Macrophagic myofasciitis

shared by Nathan Goodyear on 09 Oct 13 - No Cached
  • Nathan Goodyear on 09 Oct 13
     
    good review of the biochemistry of neuroinflammation and aluminum from Macrophagic myofasciitis.
Nathan Goodyear

Absence of chronic traumatic encephalopat... [Front Hum Neurosci. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23745112

CTE concussions football neurology chronic traumatic encephalopathy encephalopathy

shared by Nathan Goodyear on 27 Oct 13 - No Cached
  • Nathan Goodyear on 27 Oct 13
     
    Study finds that not all football players with a history of multiple concussions and neurologic symptoms have CTE.
Nathan Goodyear

Organic mercury compounds: human exposure and its relevance to public health - 0 views

tih.sagepub.com/...109.abstract

mercury organic

shared by Nathan Goodyear on 12 May 11 - No Cached
  • In general, the effects of exposure to organic mercury are primarily neurologic,
  • Nathan Goodyear on 12 May 11
     
    Organic Mercury effects are primarily neurologic
Nathan Goodyear

Practice Parameter: Treatment of nervous system Lyme disease (an evidence-based review)... - 0 views

www.neurology.org/...91.short

lyme disease neurology nervous system treatment

shared by Nathan Goodyear on 12 Sep 11 - No Cached
  • Nathan Goodyear on 12 Sep 11
     
    prolonged antibiotics not shown to be effective in post-Lyme syndrome
Nathan Goodyear

QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY ... - 0 views

brain.oxfordjournals.org/...1249.short

Kynurenine pathway quinolinic inflammtion

shared by Nathan Goodyear on 12 Apr 11 - No Cached
  • QUIN and kynurenic acid are mediators of neuronal dysfunction and nerve cell death in inflammatory diseases.
  • Nathan Goodyear on 12 Apr 11
     
    kynurenine pathway and neurological inflammation
Nathan Goodyear

Stuck at the bench: Potential natural neuroprotective compounds for concussion - 0 views

www.ncbi.nlm.nih.gov/...PMC3205506

concussions concussion natural therapies brain curcumin omega 3 resveratrol green tea EGCG EPA DHA vitamin E vitamin c vitamin D

shared by Nathan Goodyear on 20 Feb 16 - No Cached
  • Long-chain polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are highly enriched in neuronal synaptosomal plasma membranes and vesicles
  • The predominant CNS polyunsaturated fatty acid is DHA
  • effective supplementation and/or increased ingestion of dietary sources rich in EPA and DHA, such as cold-water fish species and fish oil, may help improve a multitude of neuronal functions, including long-term potentiation and cognition.
  • ...45 more annotations...
  • multiple preclinical studies have suggested that DHA and/or EPA supplementation may have potential benefit through a multitude of diverse, but complementary mechanisms
  • pre-injury dietary supplementation with fish oil effectively reduces post-traumatic elevations in protein oxidation
  • The benefits of pre-traumatic DHA supplementation have not only been independently confirmed,[150] but DHA supplementation has been shown to significantly reduce the number of swollen, disconnected and injured axons when administered following traumatic brain injury.
  • DHA has provided neuroprotection in experimental models of both focal and diffuse traumatic brain injury
  • potential mechanisms of neuroprotection, in addition to DHA and EPA's well-established anti-oxidant and anti-inflammatory properties
  • Despite abundant laboratory evidence supporting its neuroprotective effects in experimental models, the role of dietary DHA and/or EPA supplementation in human neurological diseases remains uncertain
  • Several population-based, observational studies have suggested that increased dietary fish and/or omega-3 polyunsaturated fatty acid consumption may reduce risk for ischemic stroke in several populations
  • Randomized control trials have also demonstrated significant reductions in ischemic stroke recurrence,[217] relative risk for ischemic stroke,[2] and reduced incidence of both symptomatic vasospasm and mortality following subarachnoid hemorrhage
  • Clinical trials in Alzheimer's disease have also been largely ineffective
  • The clinical evidence thus far appears equivocal
  • curcumin has gained much attention from Western researchers for its potential therapeutic benefits in large part due to its potent anti-oxidant[128,194,236] and anti-inflammatory properties
  • Curcumin is highly lipophilic and crosses the blood-brain barrier enabling it to exert a multitude of different established neuroprotective effects
  • in the context of TBI, a series of preclinical studies have suggested that pre-traumatic and post-traumatic curcumin supplementation may bolster the brain's resilience to injury and serve as a valuable therapeutic option
  • Curcumin may confer significant neuroprotection because of its ability to act on multiple deleterious post-traumatic, molecular cascades
  • studies demonstrated that both pre- and post-traumatic curcumin administration resulted in a significant reduction of neuroinflammation via inhibition of the pro-inflammatory molecules interleukin 1β and nuclear factor kappa B (NFκB)
  • no human studies have been conducted with respect to the effects of curcumin administration on the treatment of TBI, subarachnoid or intracranial hemorrhage, epilepsy or stroke
  • studies have demonstrated that resveratrol treatment reduces brain edema and lesion volume, as well as improves neurobehavioral functional performance following TBI
  • green tea consumption or supplementation with its derivatives may bolster cognitive function acutely and may slow cognitive decline
  • At least one population based study, though, did demonstrate that increased green tea consumption was associated with a reduced risk for Parkinson's disease independent of total caffeine intake
  • a randomized, placebo-controlled trial demonstrated that administration of green tea extract and L-theanine, over 16 weeks of treatment, improved indices of memory and brain theta wave activity on electroencephalography, suggesting greater cognitive alertness
  • Other animal studies have also demonstrated that theanine, another important component of green tea extract, exerts a multitude of neuroprotective benefits in experimental models of ischemic stroke,[63,97] Alzheimer's disease,[109] and Parkinson's disease
  • Theanine, like EGCG, contains multiple mechanisms of neuroprotective action including protection from excitotoxic injury[97] and inhibition of inflammation
  • potent anti-oxidant EGCG which is capable of crossing the blood-nerve and blood-brain barrier,
  • Epigallocatechin-3-gallate also displays neuroprotective properties
  • More recent research has suggested that vitamin D supplementation and the prevention of vitamin D deficiency may serve valuable roles in the treatment of TBI and may represents an important and necessary neuroprotective adjuvant for post-TBI progesterone therapy
  • Progesterone is one of the few agents to demonstrate significant reductions in mortality following TBI in human patients in preliminary trials
  • in vitro and in vivo studies have suggested that vitamin D supplementation with progesterone administration may significantly enhance neuroprotection
  • Vitamin D deficiency may increase inflammatory damage and behavioral impairment following experimental injury and attenuate the protective effects of post-traumatic progesterone treatment.[37]
  • emerging evidence has suggested that daily intravenous administration of vitamin E following TBI significantly decreases mortality and improves patient outcomes
  • high dose vitamin C administration following injury stabilized or reduced peri-lesional edema and infarction in the majority of patients receiving post-injury treatment
  • it has been speculated that combined vitamin C and E therapy may potentiate CNS anti-oxidation and act synergistically with regards to neuroprotection
  • one prospective human study has found that combined intake of vitamin C and E displays significant treatment interaction and reduces the risk of stroke
  • Pycnogenol has demonstrated the ability to slow or reduce the pathological processes associated with Alzheimer's disease
  • Pcynogenol administration, in a clinical study of elderly patients, led to improved cognition and reductions in markers of lipid peroxidase
  • One other point of consideration is that in neurodegenerative disease states like Alzheimer's disease and Parkinson's disease, where there are high levels of reactive oxygen species generation, vitamin E can tend to become oxidized itself. For maximal effectiveness and to maintain its anti-oxidant capacity, vitamin E must be given in conjunction with other anti-oxidants like vitamin C or flavonoids
  • These various factors might account for the null effects of alpha-tocopherol supplementation in patients with MCI and Alzheimer's disease
  • preliminary results obtained in a pediatric population have suggested that post-traumatic oral creatine administration (0.4 g/kg) given within four hours of traumatic brain injury and then daily thereafter, may improve both acute and long-term outcomes
  • Acutely, post-traumatic creatine administration seemed to reduce duration of post-traumatic amnesia, length of time spent in the intensive care unit, and duration of intubation
  • At three and six months post-injury, subjects in the creatine treatment group demonstrated improvement on indices of self care, communication abilities, locomotion, sociability, personality or behavior and cognitive function when compared to untreated controls
  • patients in the creatine-treatment group were less likely to experience headaches, dizziness and fatigue over six months of follow-up
  • CNS creatine is derived from both its local biosynthesis from the essential amino acids methionine, glycine and arginine
  • Studies of patients with CNS creatine deficiency and/or murine models with genetic ablation of creatine kinase have consistently demonstrated significant neurological impairment in the absence of proper creatine, phosphocreatine, or creatine kinase function; thus highlighting its functional importance
  • chronic dosing may partially reverse neurological impairments in human CNS creatine deficiency syndromes
  • Several studies have suggested that creatine supplementation may also reduce oxidative DNA damage and brain glutamate levels in Huntington disease patients
  • Another study highlighted that creatine supplementation marginally improved indices of mood and reduced the need for increased dopaminergic therapy in patients with Parkinson's disease
  • Nathan Goodyear on 20 Feb 16
     
    great review of natural therapies in the treatment of concussions
spineneuro

With Gamma Knife Treatment in India Get Personalized Treatment Approach - 0 views

www.linkedin.com/...atment-india-get-personalized-

neurological treatments gamma knife treatment gamma knife radiosurgery Dr Sandeep Vaishya best gamma knife neurosurgeon in Delhi

shared by spineneuro on 27 Dec 21 - No Cached
  • spineneuro on 27 Dec 21
     
    According to a recent survey, patients can save up to 85% of the costs when they visit India for their neurological treatments. The cost of gamma knife treatment in India is very low in comparison to the cost at best hospitals in the US or UK with the same level of care and services. Contact Details International Helpline Number : +91-9325887033 Email: enquiry@spineandneurosurgeryhospitalindia.com
Nathan Goodyear

Access : Neuroimmunology: Estrogen receptor ligands suppress inflammatory responses in ... - 0 views

www.nature.com/...nrneurol.2011.87.html

ER-beta estrogen receptors receptor MS multiple sclerosis astrocytes microglia microglial cells excitotoxic excitotoxicity disease neurology brain immune hormone hormones

shared by Nathan Goodyear on 10 Oct 12 - No Cached
  • Nathan Goodyear on 10 Oct 12
     
    Granted, this study was in an animal model of MS, but signaling through ER-beta was shown to decrease inflammation from astrocytes and microglial cells in the brain.  These immune cells are known to play prominent roles in excitotoxic diseases such as MS.  So, again, it is not just about the message, but also about how the message is interpreted.
Nathan Goodyear

https://dl-web.dropbox.com/get/Public/Research/ane_7212-1.pdf?w=AABZMjLPg8k92S9AxmjD0IN... - 0 views

dl-web.dropbox.com/...ane_7212-1.pdf

Hg Mercury toxicity poisoning autism ASD

shared by Nathan Goodyear on 07 Mar 13 - No Cached
  • Nathan Goodyear on 07 Mar 13
     
    Good non biased look at heavy metals, particularly Hg, and autism.  The authors of this study found the same neurologic pathology biochemically in Hg poisoning as in autism.  
Nathan Goodyear

JAMA Network | JAMA Neurology | Refractory Nonmotor Symptoms in Male Patients With Park... - 0 views

archneur.jamanetwork.com/article.aspx

testosterone Parkinson's Parkinson's disease therapy low T treatment inflammation neurodegenerative disease excitotoxicity neurology male

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone therapy aids symptoms of Parkinson's disease.  Whether low T is an associated finding or plays a role has yet to be determined.  However, we do know that androgens play an anti-inflammatory role in men and we know that inflammation plays a role in the neurodegenerative disease that is Parkinson's disease.
Nathan Goodyear

JAMA Network | JAMA Neurology | Beneficial Effects of Testosterone Replacement for the ... - 0 views

archneur.jamanetwork.com/article.aspx

testosterone therapy treatment Parkinson's parkinson's disease non motor symptoms neurology

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone shown to provide benefit for non motor Parkinson symptoms.
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