Bioavailable Testosterone and Depressed Mood in Older Men: The Rancho Bernardo Study: T... - 0 views
bioavailable testosterone levels decrease much more with age than does total testosterone or estradiol levels
The decrease in bioavailable testosterone parallels the increase in sex hormone binding globulin with age, a change that accompanies increasing body fat independent of weight change
a graded stepwise decrease in bioavailable testosterone with increasing level of depressed mood
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This association was independent of age, weight change, and physical activity, the only three significant confounding covariates of the association between sex hormone levels and BDI scores