Skip to main content

Home/ Seasons Wellness/ Group items tagged astrocytes

Rss Feed Group items tagged

Nathan Goodyear

Membrane Estrogen Receptors Stimulate Intracellular Calcium Release and Progesterone Sy... - 0 views

  •  
    Estradiol stimulates hypothalamic progesterone synthesis in astrocytes in rat model.  This occurs through activation of calcium channels and influx of calcium.  ER alpha appears to be the prominent ER involved.
Nathan Goodyear

Methylmercury induces oxidative injury, alterations in permeability and glutamine trans... - 0 views

  •  
    methylmercury mediates neurotoxicity via mitochondrial damage, inflammation, and oxidative stress.  Astrocytes accumulated the methyl mercury.  The destruction of the astrocytes will result in an increase in glutamate.  Methylmercury is synergistic with other toxins in the development of immunoexcitotoxicity.
Nathan Goodyear

Aluminum induced immunoexcitotoxicity in neurodevelopmental and neurodegenerative disor... - 0 views

  •  
    Great review of the scientific evidence of Aluminum in microglial activation and immunoexcitotoxicity and neurodegeneration of the brain.
Nathan Goodyear

Aluminum-induced Defective Mitochondrial Metabolism Perturbs Cytoskeletal Dynamics in H... - 0 views

  •  
    Aluminum destructive to astrocytes in the brain.
Nathan Goodyear

Kynurenine Metabolites and Migraine: Experimental Studies and Therapeutic Perspectives - 0 views

  •  
    Disordered tryptophan metabolism and migraine headaches.
Nathan Goodyear

Age Increase of Estrogen Receptor-α (ERα) in Cortical Astrocytes Impairs Neur... - 0 views

  •  
    increased ER-alpha expression associated with decreased neurotrophic activity.  A decrease in the neurotrophic activity of the aging brain is associated with many of the diseases of the aging brain.

    The major point here is that ER-alph is known to increase inflammatory signaling.  So increased inflammation, just via the ER receptors, plays a role in the aging brain.
Nathan Goodyear

Access : Neuroimmunology: Estrogen receptor ligands suppress inflammatory responses in ... - 0 views

  •  
    Granted, this study was in an animal model of MS, but signaling through ER-beta was shown to decrease inflammation from astrocytes and microglial cells in the brain.  These immune cells are known to play prominent roles in excitotoxic diseases such as MS.  So, again, it is not just about the message, but also about how the message is interpreted.
Nathan Goodyear

Astrocytes and therapeutics for Parkinson'... [Neurotherapeutics. 2010] - PubMed - NCBI - 0 views

  •  
    astrocytes play role in neurodegenerative disorders.
Nathan Goodyear

Untitled Page - 0 views

  •  
    review of inflammation, glutamic acid, glial activation and depression
1 - 9 of 9
Showing 20 items per page