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Nathan Goodyear

Brain dopamine and obesity : The Lancet - 0 views

www.thelancet.com/...fulltext

dopamine BMI obesity overweight

shared by Nathan Goodyear on 27 Feb 12 - No Cached
  • Nathan Goodyear on 27 Feb 12
     
    Dopamine found to be inversely associated with BMI.  The higher the BMI, the lower the dopamine levels.  This low dopamine would result in a proposed "pathological eating".  As dopamine is the "pleasure" neurotransmitter, it would be easy to see how low dopamine would result in overeating.
Nathan Goodyear

Brain dopamine transporters in obesity -- Yao et al. 51 (1002): 1820 -- Society of Nucl... - 0 views

jnumedmtg.snmjournals.org/...1820

dopamine transporters obesity receptors brain

shared by Nathan Goodyear on 29 Apr 11 - No Cached
  • The dopaminergic deficiency mechanism in obesity may primarily involve in dopamine receptors, but not dopamine transporters in a subset of non-binge eating obesity
  • Nathan Goodyear on 29 Apr 11
     
    Dopamine transporters don't appear to have role in overeating and obesity; more likely involves dopamine receptors
Nathan Goodyear

PLOS ONE: Testosterone Induces Molecular Changes in Dopamine Signaling Pathway Molecule... - 0 views

journals.plos.org/...article

testosterone dopamine hormone hormones

shared by Nathan Goodyear on 19 Jun 15 - No Cached
  • The majority of the gene expression changes reported here are only induced by DHT and testosterone, and not by estradiol, indicating that in adolescent males androgen receptor, not ERα, activation is critical for these responses
  • It is less clear whether ERβ is involved or not as DHT, via conversion to 3β-diol has a high affinity for ERβ
  • the testosterone-induced, AR-driven modulation of molecular indices of dopamine responsivity of the nigrostriatal pathway may involve regulation of dopamine feedback inhibition in the somatodendritic field and post-synaptic dopamine action in the terminal field.
  • Nathan Goodyear on 19 Jun 15
     
    Testosterone increases dopamine signaling.  This study was done on male rats.  No effect was seen with Estradiol.
Nathan Goodyear

Scientists Find Link Between Dopamine and Obesity - 0 views

www.bnl.gov/...bnlpr020101.htm

obesity dopamine

shared by Nathan Goodyear on 29 Apr 11 - No Cached
  • Nathan Goodyear on 29 Apr 11
     
    dopamine and dopamine receptors play role in obesity
Nathan Goodyear

Dopamine-based reward circuitry responsivity, genetics, and overeating. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21243471

sugar dopamine receptors overweight obese obesity sucrose

shared by Nathan Goodyear on 26 Mar 15 - No Cached
  • Nathan Goodyear on 26 Mar 15
     
    low dopamine Rc associated appears to increase addiction to sugar and its positive effect on these same receptors (and another that positively interacts with dopamine Rc's) and results in overeating and weight problems.
Nathan Goodyear

The role of dopamine receptors in the treatment of congestive heart failure. - PubMed -... - 0 views

www.ncbi.nlm.nih.gov/...2478806

dopamine CHF heart failure heart

shared by Nathan Goodyear on 01 Jun 17 - No Cached
  • Nathan Goodyear on 01 Jun 17
     
    Dopamine improves chronic CHF via its interactions with the dopamine receptors.
Nathan Goodyear

Neuropsychopharmacology - Striatal Dopaminergic and Serotonergic Markers in Human Heroi... - 0 views

www.nature.com/...1395617a.html

dopamine serotonin heroin opiates brain

shared by Nathan Goodyear on 19 Aug 14 - No Cached
  • Nathan Goodyear on 19 Aug 14
     
    study points to a modest decrease in dopamine and serotonin production in heroic users.  There appears to be a decrease in dopamine production, which could be via a down regulation of tyrosine hydroxylase enzyme and thus release.  Decreased homovanillate also noted.  Other studies have pointed to a decrease/downregulation of D2/D3 receptors.
Nathan Goodyear

Brain dopamine and obesity : The Lancet - 0 views

www.thelancet.com/...fulltext

brain dopamine D2 receptors BMI obesity overweight neurotransmitters

shared by Nathan Goodyear on 28 Mar 12 - No Cached
  • Nathan Goodyear on 28 Mar 12
     
    low Brain dopamine D2 receptors found to be inversely associated with BMI. 
Nathan Goodyear

Interaction Between Ascorbic Acid and Dopamine D2 Receptor in the Nucleus Accumbens She... - 0 views

scialert.net/fulltext

vitamin C dopamine receptors food ascorbic acid

shared by Nathan Goodyear on 08 Mar 12 - No Cached
  • Nathan Goodyear on 08 Mar 12
     
    vitamin C shown to interact with dopamine receptors and decrease food intake.
Nathan Goodyear

Luteinizing hormone secretion and hypoandrogenaemia in critically ill men: effect of do... - 0 views

onlinelibrary.wiley.com/...abstract

low T Testosterone men dopamine LH

shared by Nathan Goodyear on 18 Mar 14 - No Cached
  • Nathan Goodyear on 18 Mar 14
     
    Decreased pulse amplitude and Testosterone in ill men.  The addition of dopamine for vascular effects worsened these findings.
Nathan Goodyear

Testosterone Induces Molecular Changes in Dopamine Signaling Pathway Molecules in the A... - 0 views

www.ncbi.nlm.nih.gov/...PMC3949980

Testosterone dopamine male men hormone hormones

shared by Nathan Goodyear on 18 Mar 14 - No Cached
  • Nathan Goodyear on 18 Mar 14
     
    Testosterone modulates dopaminergic pathways in the the brain.  This was a rat model.  This points to some of the euphoria experienced by men on Testosterone likely occurs through dopamine.
Nathan Goodyear

Targeting Dopamine in Acute Traumatic Brain Injury - 0 views

www.ncbi.nlm.nih.gov/...PMC3269831

TBI traumatic brain injury dopamine brain brain injury concussion PCS post concussion syndrome

shared by Nathan Goodyear on 21 Feb 16 - No Cached
  • Nathan Goodyear on 21 Feb 16
     
    great read on the current understanding of dopamine in TBI--essentially an excitotoxic story.
Nathan Goodyear

Dopamine and male sexual function. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11805404

dopamine ED erectile dysfunction erection

shared by Nathan Goodyear on 21 May 17 - No Cached
  • Nathan Goodyear on 21 May 17
     
    dopamine plays role in erections in men.
Nathan Goodyear

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Me... - 0 views

journals.plos.org/...article

dopamine melatonin sleep

shared by Nathan Goodyear on 07 Jun 17 - No Cached
  • Nathan Goodyear on 07 Jun 17
     
    dopamine inhibits melatonin production and release disrupting sleep.
Nathan Goodyear

Role of dopamine in congestive heart failure: a contemporary appraisal. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12189316

dopamin CHF heart failure heart

shared by Nathan Goodyear on 01 Jun 17 - No Cached
  • Nathan Goodyear on 01 Jun 17
     
    dopamine has benefit in CHF.  Actually, use to be a therapy employed.
Nathan Goodyear

PLOS ONE: N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Prelim... - 0 views

journals.plos.org/...article

Parkinsons Parkinson's disease NAC N-acetylcysteine brain

shared by Nathan Goodyear on 17 Jun 16 - No Cached
  • Nathan Goodyear on 17 Jun 16
     
    pilot study finds that NAC protects the dopaminergic neurons in the brains in cell line stud.  Clinical found increased dopamine binding in the brain compared to placebo in individuals with Parkinson's disease.
Nathan Goodyear

Figure 1 : The therapeutic potential of monoamine oxidase inhibitors : Nature... - 0 views

www.nature.com/...nrn1883_F1.html

dopamin metabolism MAO-A MAO-B Parkinson's Disease

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    Monoamine oxidase A and B effect on dopamine metabolism
Nathan Goodyear

Sensory Processing Disorder in a Primate Model: Evidence From a Longitudinal Study of P... - 0 views

onlinelibrary.wiley.com/...full

sensory processing disorder dopamine BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Good discussion of sensory processing disruption, dopamine, and BDNF.  This study specifically looked at a monkey model.
Nathan Goodyear

ScienceDirect - Journal of Psychiatric Research : Neuroendocrine effects of S-adenosyl-... - 0 views

www.sciencedirect.com/science

SAMe dopamine depression

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • Our results, at least in depressed men, seem to support the hypothesis of a stimulating effect of SAMe on the dopaminergic system
  • Nathan Goodyear on 08 Mar 11
     
    SAMe stimulates dopamine secretion in depressed men
Nathan Goodyear

PRECLINICAL STUDY: Changes in central dopaminergic systems and morphine reward by prena... - 0 views

onlinelibrary.wiley.com/...full

bisphenol-A bisphenol A BPA dopamine mesolimbic lactation organogenesis prenatal exposure

shared by Nathan Goodyear on 10 Oct 11 - No Cached
  • Nathan Goodyear on 10 Oct 11
     
    great study that shows how BPA exposure has its largest impact on the mesolimbic/dopamine system during organogenesis and lactation periods.
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