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Nathan Goodyear

JAMA Network | JAMA Neurology | Refractory Nonmotor Symptoms in Male Patients With Park... - 0 views

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    Testosterone therapy aids symptoms of Parkinson's disease.  Whether low T is an associated finding or plays a role has yet to be determined.  However, we do know that androgens play an anti-inflammatory role in men and we know that inflammation plays a role in the neurodegenerative disease that is Parkinson's disease.
Nathan Goodyear

Differential neuroprotective and antiinflammatory effects of estrogen recepto... - 0 views

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    ER-beta as anti-inflammatory and neuroprotective?  According to this review, yes.
Nathan Goodyear

The Danger of Excessive Vaccination During Brain Development - 0 views

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    Dr. Blaylock, neurosurgeon, on the detrimental effects of excessive vaccinations in our children.  This is heavily referenced.
Nathan Goodyear

DORway » Aspartame & Aspartame Poisoning Information Site - 0 views

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    lengthy but extremely thorough explanation of excitotoxicity and Autism.  This is heavily referenced and should be read by all!  A good discussion on how immune stimulation in the developing brain contributes to ASD...hint: vaccines.
Nathan Goodyear

Microglial Activation And Neurodegeneration - 0 views

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    short and brief discussion of how microglial inflammation cause neurodegeneration via excitotoxicity.  Dr. Blaylock is the author of this short article.  
Nathan Goodyear

Access : Neuroimmunology: Estrogen receptor ligands suppress inflammatory responses in ... - 0 views

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    Granted, this study was in an animal model of MS, but signaling through ER-beta was shown to decrease inflammation from astrocytes and microglial cells in the brain.  These immune cells are known to play prominent roles in excitotoxic diseases such as MS.  So, again, it is not just about the message, but also about how the message is interpreted.
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unify... - 0 views

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    great analysis of immunoexcitoxicity and it's pathophysiologic role in CTE.
Nathan Goodyear

A possible central mechanism in autism spectrum disorders, Part 2: Immunoexcitotoxicity - 0 views

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    Must read on immunoexcitotoxicity by Dr. Blaylock. Discuss on the biochemical changes found in ASD and the associated precipitants
Nathan Goodyear

The Danger of Excessive Vaccination During Brain Development at News Forum (MessageID: ... - 0 views

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    Fantastic discussion and review of the biochemical effects of vaccinations on the developing child's brain.  This article is authored by Dr. Blaylock, a neurosurgeon and expert in excitotoxicity.
Nathan Goodyear

Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2) - 0 views

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    vitamin C proposed to have therapeutic effect in those with stroke, Alzheimer's disease, Parkinson's disease, and Huntingdon's disease.
Nathan Goodyear

Ascorbate inhibits edema in brain slices. | Mendeley - 0 views

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    vitamin C shown to reduce brain edema associated with glutamate excitotoxicity
Nathan Goodyear

Calcium: A target in the war on Alzheimer's disease - 0 views

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    good discussion on Alzheimer's disease and the role of calcium
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unify... - 0 views

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    immunoexcitotoxicity and traumatic brain injury
Nathan Goodyear

IOS Press - Journal Article - 0 views

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    neuroinflammaiton, also described as excitotoxicity, found in the brains of children/young adults that lived in high air pollution areas.  Neuroinflammation (IL-6, IL-1, TNF-alpha, IFN-gamma...) found in the brains of these children and young adults.  This is the same process found in Alzheimers and other excitotoxicity disease states.  Addtionally, it is also involved in most chronic diseases of aging.
Nathan Goodyear

CNS Spectrums: Inflammation, Glutamate, and Glia in Depression: A Literature Review - 0 views

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    inflammation, glutamate excitotoxicity and depression.  A very nice review of how inflammation can remotely contribute to other arenas of dysfunction, ie. depression.
Nathan Goodyear

CONTRIBUTION OF A MITOCHONDRIAL PATHWAY TO EXCITOTOXIC NEURONAL NECROSIS - 0 views

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    mitochondria dysfunction contributes to excitotoxicity disorders.
Nathan Goodyear

ScienceDirect - Cell Calcium : Molecular mechanisms of calcium-dependent neurodegenerat... - 0 views

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    proposed mechanism of calcium involvement in excitotoxicity
Nathan Goodyear

Pictorial Review of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging - 0 views

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    excellent article on the imaging of excitotoxicity.  Glutamate excitotoxicity is a key component in neurodegenerative diseases: Alzheimers, Parkinsons, ALS, MS...
Nathan Goodyear

Characterization of the Kynurenine Pathway in Human Neurons - 0 views

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    review of the kynurenine pathway 
Nathan Goodyear

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States - 0 views

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    review of studies looking at kyneurenine pathway and it's contribution to neurodegenerative disorders and mood disorders
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