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Nathan Goodyear

Pictorial Review of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging - 0 views

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    excellent article on the imaging of excitotoxicity.  Glutamate excitotoxicity is a key component in neurodegenerative diseases: Alzheimers, Parkinsons, ALS, MS...
Nathan Goodyear

IOS Press - Journal Article - 0 views

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    neuroinflammaiton, also described as excitotoxicity, found in the brains of children/young adults that lived in high air pollution areas.  Neuroinflammation (IL-6, IL-1, TNF-alpha, IFN-gamma...) found in the brains of these children and young adults.  This is the same process found in Alzheimers and other excitotoxicity disease states.  Addtionally, it is also involved in most chronic diseases of aging.
Nathan Goodyear

Molecular mechanisms of excitotoxicity and their r... [Acta Pharmacol Sin. 2009] - PubM... - 0 views

  • is review discusses the current understanding of excitotoxic mechanisms and how they are involved in the pathogenesis of neurodegenerative diseases.
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    nice review on excitotoxicity and neurodegenerative diseases
Nathan Goodyear

Access : Neuroimmunology: Estrogen receptor ligands suppress inflammatory responses in ... - 0 views

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    Granted, this study was in an animal model of MS, but signaling through ER-beta was shown to decrease inflammation from astrocytes and microglial cells in the brain.  These immune cells are known to play prominent roles in excitotoxic diseases such as MS.  So, again, it is not just about the message, but also about how the message is interpreted.
Nathan Goodyear

DORway » Aspartame & Aspartame Poisoning Information Site - 0 views

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    lengthy but extremely thorough explanation of excitotoxicity and Autism.  This is heavily referenced and should be read by all!  A good discussion on how immune stimulation in the developing brain contributes to ASD...hint: vaccines.
Nathan Goodyear

CONTRIBUTION OF A MITOCHONDRIAL PATHWAY TO EXCITOTOXIC NEURONAL NECROSIS - 0 views

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    mitochondria dysfunction contributes to excitotoxicity disorders.
Nathan Goodyear

ScienceDirect - Cell Calcium : Molecular mechanisms of calcium-dependent neurodegenerat... - 0 views

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    proposed mechanism of calcium involvement in excitotoxicity
Nathan Goodyear

[Role of glutamate and excitotoxicity in neurologi... [Rev Neurol (Paris). 1996] - PubM... - 0 views

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    nice abstract on the basic physiologic role of glutamate excitotoxicity
Nathan Goodyear

The role of excitotoxicity in neurodegenerative di... [Pharmacol Ther. 1999] - PubMed r... - 0 views

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    excitotoxicity and contribution to neurodegenerative disease
Nathan Goodyear

Pictorial Review of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging -- ... - 0 views

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    Very heavy, but good read on glutamate excitotoxicity
Nathan Goodyear

Molecular mechanisms of calcium-dependent neurodeg... [Cell Calcium. 2003 Oct-Nov] - Pu... - 0 views

  • Key mediators of excitotoxic damage are Ca ions (Ca(2+))
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    Calcium involved in excitotoxicity
Nathan Goodyear

Microglial Activation And Neurodegeneration - 0 views

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    short and brief discussion of how microglial inflammation cause neurodegeneration via excitotoxicity.  Dr. Blaylock is the author of this short article.  
Nathan Goodyear

Exercise increases mitochondrial glutamate oxidation in the mouse cerebral cortex - App... - 0 views

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    exercise found to reduce glutamate excitotoxicity in mouse study.
Nathan Goodyear

The Danger of Excessive Vaccination During Brain Development at News Forum (MessageID: ... - 0 views

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    Fantastic discussion and review of the biochemical effects of vaccinations on the developing child's brain.  This article is authored by Dr. Blaylock, a neurosurgeon and expert in excitotoxicity.
Nathan Goodyear

CNS Spectrums: Inflammation, Glutamate, and Glia in Depression: A Literature Review - 0 views

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    inflammation, glutamate excitotoxicity and depression.  A very nice review of how inflammation can remotely contribute to other arenas of dysfunction, ie. depression.
Nathan Goodyear

Ascorbate inhibits edema in brain slices. | Mendeley - 0 views

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    vitamin C shown to reduce brain edema associated with glutamate excitotoxicity
Nathan Goodyear

Taurine prevents the neurotoxicity of beta-amyloid... [FASEB J. 2004] - PubMed result - 0 views

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    Taurine, an amino acid, and melatonin, a hormone, both aid in decreasing excitotoxicity in Parkinson's disease
Nathan Goodyear

Mitoenergetic failure in Alzheimer disease - 0 views

  • This review summarizes new insights based on the interaction of mitoenergetic failure, glutamate excitotoxicity, and amyloid toxicity in the exacerbation of AD.
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    discussion on mitochondria, neuro-excitotoxicity, and Alzheimer's Disease
Nathan Goodyear

Glutamate and the glutamate receptor system: a tar... [Int J Geriatr Psychiatry. 2003] ... - 0 views

  • Under certain conditions, glutamate has a toxic action resulting from an activation of specific glutamate receptors, which leads to acute or chronic death of nerve cells.
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    deep, heavy read on glutamate excitotoxicity and neuronal death leading to neurodegenerative disease
Nathan Goodyear

Coenzyme Q10 Decreases Amyloid Pathology an... [J Alzheimers Dis. 2011] - PubMed - NCBI - 0 views

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    CoQ10 shown to benefit excitotoxic diseases such as Alzheimer's disease, Parkinson's, MS...
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