Skip to main content

Home/ Dr. Goodyear/ Group items tagged neurotrophic

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Age Increase of Estrogen Receptor-α (ERα) in Cortical Astrocytes Impairs Neur... - 0 views

endo.endojournals.org/...2101.abstract

ER alpha ER-alpha ER estrogen receptors brain neurology neurotrophic astrocytes

shared by Nathan Goodyear on 24 Jun 13 - No Cached
  • Nathan Goodyear on 24 Jun 13
     
    increased ER-alpha expression associated with decreased neurotrophic activity.  A decrease in the neurotrophic activity of the aging brain is associated with many of the diseases of the aging brain. The major point here is that ER-alph is known to increase inflammatory signaling.  So increased inflammation, just via the ER receptors, plays a role in the aging brain.
Nathan Goodyear

DHA dietary supplementation enhances the effects of exercise on synaptic plasticity and... - 0 views

www.ncbi.nlm.nih.gov/...PMC3208643

DHA n-3 omega 3 omega-3 fish oil cognition memory hippocampus exercise neuroplasticity BDNF brain derived neurotrophic factor lipid peroxidation

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • Nathan Goodyear on 01 Nov 13
     
    DHA enriched diet plus exercis improved cognition through a increase in brain derived neurotrophic factor (BDNF).  The result was increased neuroplasticity.  Additionally, they were shown to reduce hippocampal lipid peroxidation.
Nathan Goodyear

Neuron - Epigenetic Status of Gdnf in the Ventral Striatum Determines Susceptibility an... - 0 views

www.cell.com/...S0896627310010718

stress depression methylation glial cell-derived neurotrophic factor Gdnf

shared by Nathan Goodyear on 10 Oct 11 - No Cached
  • Nathan Goodyear on 10 Oct 11
     
    How you respond to stress is a reflection of your genetics and environment.  The bodies ability to express genes, such as the glial cell-derived neurotrophic factor, impacts an individual's expression in the face of stress.  You have a genetic predisposition, but with poor methylation you end up with more depression in the presence of stress
Nathan Goodyear

An Overview of Brain-Derived Neurotrophic Factor and Implications for Excitotoxic Vulne... - 0 views

www.hindawi.com/...654085

BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    great review of BDNF and neurogenesis.
Nathan Goodyear

Brain-derived Neurotrophic Factor in Human Saliva: ELISA Optimization and Biological Co... - 0 views

www.ncbi.nlm.nih.gov/...PMC3046426

saliva BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    BDNF can be found and followed in saliva
Nathan Goodyear

Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of ste... - 0 views

www.ncbi.nlm.nih.gov/...PMC1778460

estrogen estradiol BDNF brain derived neurotrophic factor brain hippocampus

shared by Nathan Goodyear on 26 Mar 15 - No Cached
  • Nathan Goodyear on 26 Mar 15
     
    Estrogen effects in the hippocampus with BDNF (surprise, surprise) appear to have different effects between the sexes.
Nathan Goodyear

The combined effects of exercise and foods in preventing neurological and cognitive dis... - 0 views

www.ncbi.nlm.nih.gov/...PMC3258093

diet nutrition exercise BDNF omega-3 omega 3 n-3 brain derived neurotrophic factor curcumin polyphenols neuroplasticity memory sugar saturated fats

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • The most prevalent types of cognitive impairments include disturbances in attention and learning and memory function
  • An association between BDNF and learning and memory was found when measuring the performance of rats on the Morris water maze task
  • exercise and BDNF have been associated with reducing depression and promoting cognitive enhancement.
  • ...3 more annotations...
  • In addition to reducing oxidative stress and inflammation, DHA serves to improve neuronal function by supporting synaptic membrane fluidity
  • Curcumin has also been shown to protect the hippocampus and to counteract learning impairment
  • insufficient DHA in the brain can compromise neuronal function with subsequent effects on a broad range of neurological and behavioral faculties.
  • Nathan Goodyear on 01 Nov 13
     
    diet and exercise increases BDNF.  Diets rich in omega 3, curcumin, and polyphenols increase BDNF and thus increase neuroplasticity and associated cognition.   In contrast, sugar and saturated fats in crease oxidative stress and worsened spatial learning.  This study is a review.  
Nathan Goodyear

Dietary omega-3 fatty acids normalize BDNF lev... [J Neurotrauma. 2004] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15672635

BDNF n-3 omega 3 omega-3 oxidative stress inflammation brain derived neurotrophic factor

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Another rat study as alot of the studies are with BDNF.  Dietary n-3 reduce oxidative stress and inflammation and increase BDNF.
Nathan Goodyear

Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects o... - 0 views

www.ncbi.nlm.nih.gov/...PMC2805663

BDNF hippocampus memory brain MAPK

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    BDNF increased metabolic biomarkers, MAPK, in hippocampus.  This has implications in the treatment of learning disorders.  Exercise has consistently been shown to be the most significant mechanism to increase BDNF.
Nathan Goodyear

Sensory Processing Disorder in a Primate Model: Evidence From a Longitudinal Study of P... - 0 views

onlinelibrary.wiley.com/...full

sensory processing disorder dopamine BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Good discussion of sensory processing disruption, dopamine, and BDNF.  This study specifically looked at a monkey model.
Nathan Goodyear

KoreaMed Synapse - 0 views

synapse.koreamed.org/search.php

BDNF brain derived neurotrophic factor stress bipolar disorder disease neuroplasticity

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Stress plays role in BDNF levels.  A decrease in BDNF is found in bipolar patients.  Stress will reduce neuroplasticity through a reduction in BDNF.
Nathan Goodyear

DHA dietary supplementation enhances the effects of exercise on synaptic plasticity and... - 0 views

www.ncbi.nlm.nih.gov/...PMC3208643

DHA n-3 omega 3 omega-3 BDNF brain derived neurotrophic factor neuroplasticity cognition

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Animal study finds that DHA increases BDNF increasing neuroplasticity.
Nathan Goodyear

Intrathecal epigallocatechin gallate treatment... [Neurochem Res. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23344852

EGCG green tea BDNF brain derived neurotrophic factor neuroplasticity

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    This rat model found that EGCG promoted neuro-recovery and neuroprotection through BDNF and GDNF in spinal cord injury model.
Nathan Goodyear

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusi... - 0 views

www.sciencedirect.com/...S0014488604004431

BDNF brain derived neurotrophic factor hippocampus memory neuroplasticity

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    BDNF promotes neurogenesis in the hippocampus.  BDNF promotes neuroplasticity.
Nathan Goodyear

Scopus preview - Scopus - Document details - 0 views

www.scopus.com/...display.url

BDNF brain derived neurotrophic factor neuroplasticity

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    BDNF promotes neurogenesis
Nathan Goodyear

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseas... - 0 views

www.nature.com/...nrn3505.html

BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 06 Nov 13 - No Cached
  • Nathan Goodyear on 06 Nov 13
     
    BDNF should be the focus of any cognitive and neurodegenerative disease.
Nathan Goodyear

Dietary Strategy to Repair Plasma Membrane After Brain Trauma - 0 views

nnr.sagepub.com/...75.long

curcumin DHA TBI traumatic brain injury brain injury neuroinflammation BDNF brain derived neurotrophic factor brain

shared by Nathan Goodyear on 31 Aug 15 - No Cached
  • concussive brain injury is a major cause of neuropsychological disability in spite of no obvious neuronal death
  • TBI elicits oxidative damage to plasma membrane phospholipids
  • DHA is the most abundant polyunsaturated fatty acid (PUFA) in the brain, where the DHA-containing phospholipids contribute to plasma membrane biogenesis and receptor signaling
  • ...10 more annotations...
  • curcumin has potent anti-inflammatory and antioxidant activities that can function to reduce oxidative damage and cognitive deficits associated with neurological disorders
  • Curcumin provided in the diet before TBI can reduce oxidative damage and counteract TBI-related cognitive dysfunction
  • Our previous study indicated that n-3 fatty acids supplemented in the diet counteracted learning disability after TBI
  • curcumin contributes to enhance the effects of DHA on TBI by promoting phosphorylation of the BDNF receptor TrkB in the hippocampus
  • previous evidence indicates that curcumin10 and DHA5 counteract TBI-related learning disability by involving BDNF
  • Our findings indicate that curcumin counteracted the TBI-related reduction in n-3 DPA.
  • curcumin may promote the conversion of n-3 DPA to DHA
  • the combination of both nutrients has been reported to produce anti-inflammatory action
  • the enhanced actions of curcumin and DHA in reducing cholesterol levels could be interpreted as preservation of levels of phospholipids in the plasma membrane
  • curcumin and DHA may contribute to reduce inflammation associated with the action of cholesterol in the pathology of TBI.
  • Nathan Goodyear on 31 Aug 15
     
    Curcumin and DHA shown to protect against TBI through a reduction in inflammation and maintenance of brain phospholipid membranes.  BDNF is increases also.
Nathan Goodyear

Associations between brain-derived neu... [Neuro Endocrinol Lett. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24977975

BDNF brain derived neurotrophic factor Estradiol Estrogen women female hormone hormones brain health mental

shared by Nathan Goodyear on 23 Aug 14 - No Cached
  • Nathan Goodyear on 23 Aug 14
     
    BDNF correlates with Estradiol in women.
Nathan Goodyear

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway: Cell Metabo... - 0 views

www.cell.com/...S1550-4131(13)00377-X

brain memory focus attention learning exercise BDNF brain derived neurotrophic factor PGC-1alpha irisin FNDC5 hippocampus cognition

shared by Nathan Goodyear on 12 Aug 14 - No Cached
  • Nathan Goodyear on 12 Aug 14
     
    Brain benefits of exercise explained.  Exercise increases hippocampal BDNF via PGC-1alpha from skeletal muscle.
Nathan Goodyear

Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after... - 0 views

www.hindawi.com/...512978

hbot hyperbaric hyperbaric therapy brain MPO stroke neurogenesis BDNF brain derived neurotrophic factor

shared by Nathan Goodyear on 18 May 17 - No Cached
  • Nathan Goodyear on 18 May 17
     
    animal study finds that HBOT reduced stroke infarct size, increased neurogenesis, increased BDNF, and reduced MPO.
1 - 20 of 20
Showing 20▼ items per page