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herbnclay

Calcium Bentonite Clay Benefits - Internal and External Uses - 0 views

www.herbnclay.com/fits-of-calcium-bentonite-clay

best clay mask for oily skin green powder uses natural healing

shared by herbnclay on 23 Jan 18 - No Cached
  • herbnclay on 23 Jan 18
     
    HERB n' CLAY provides you with 100 percent all natural Calcium Bentonite Clay. Bentonite clay has microscopic layers through which it absorbs the toxins in our bowels. It contains silica with high traces of Calcium. In addition there are more than 50 trace elements in Calcium Bentonite Clay.
Nathan Goodyear

Effects of dietary calcium compared with calcium supplements on estrogen metabolism and... - 0 views

www.ajcn.org/...1428.abstract

calcium dietary supplement supplementation bone density mineral

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Nathan Goodyear on 15 Aug 11
     
    dietary calcium proves to be better source than Calcium supplement
Nathan Goodyear

Selective Inhibition of L-Type Ca2+ Channels in A7r5 Cells by Physiological Levels of T... - 0 views

endo.endojournals.org/...2675

testosterone vasodilation calcium channel blocker cardiovascular CVD calcium channel blocker

shared by Nathan Goodyear on 14 May 13 - No Cached
  • Nathan Goodyear on 14 May 13
     
    Physiologic levels of testosterone shown to induce Calcium channel blockade.  This induces the beneficial cardiovascular vasodilation.  It is known that testosterone binds to the same receptor as the common calcium channel blocker nifedipine.
Nathan Goodyear

Membrane Estrogen Receptors Stimulate Intracellular Calcium Release and Progesterone Sy... - 0 views

www.jneurosci.org/...12950.full

estradiol estrogen progesterone hypothalamus receptors ER ER-alpha ER alpha hormones CNS astrocytes brain calcium channels

shared by Nathan Goodyear on 10 Mar 14 - No Cached
  • Nathan Goodyear on 10 Mar 14
     
    Estradiol stimulates hypothalamic progesterone synthesis in astrocytes in rat model.  This occurs through activation of calcium channels and influx of calcium.  ER alpha appears to be the prominent ER involved.
Nathan Goodyear

Hypercalcemia of malignancy and new treatment options - 0 views

www.ncbi.nlm.nih.gov/...PMC4675637

hypercalcemia calcium cancer

shared by Nathan Goodyear on 11 Sep 18 - No Cached
  • Hypercalcemia of malignancy occurs as the result of direct bone metastasis and via humoral mechanisms such as parathyroid hormone-related protein (PTHrP) or 1,25-dihydroxyvitamin D mediated pathways
  • ectopic secretion of parathyroid hormone (PTH) has been implicated
  • Hypercalcemia due to osteolytic bone lesions is common in multiple myeloma, leukemia, and breast cancer
  • ...22 more annotations...
  • Humoral hypercalcemia is predominant in squamous cell, renal cell and ovarian cancers, and lymphomas are associated with 1,25-dihydroxyvitamin D mediated hypercalcemia
  • 20% of cases of hypercalcemia of malignancy and is frequently encountered in multiple myeloma, metastatic breast cancer, and to a lesser extent in leukemia and lymphoma
  • Physiologic bone turnover requires the complementary activity of osteoblasts – mesenchymal stem cell-derived bone-forming cells – and bone-resorbing cells of monocyte and macrophage lineage known as osteoclasts
  • In local osteolytic hypercalcemia, the RANKL/RANK interaction results in excessive osteoclast activation leading to enhanced bone resorption and thus hypercalcemia
  • In addition, osteoclast activation is also mediated by malignancy secreted cytokines, including interleukin-1, initially termed “osteoclast stimulating factor”
  • Macrophage inflammation protein 1-alpha (MIP 1-alpha)
  • hypercalcemia is through extra-renal 1,25-dihydroxyvitamin D (calcitriol) production
  • 1% of cases
  • increased production of 1,25-dihydroxyvitamin D occurs nearly exclusively in Hodgkin and non-Hodgkin lymphoma with case reports of the same in ovarian dysgerminoma
  • 1-α-hydroxylase in the kidney, a process regulated by PTH
  • in 1,25-dihydroxyvitamin D induced hypercalcemia, malignant cells likely recruit and induce adjacent macrophages to express 1-α-hydroxylase, converting endogenous calcidiol into calcitriol.31 Calcitriol then binds to receptors in the intestine leading to heightened enteric calcium reabsorption with resultant hypercalcemia
  • this mechanism of disease is best conceptualized as an absorptive form of hypercalcemia
  • Ectopic production of PTH by malignant cells has been described in a handful of cases involving cancer of the ovary and lung, as well as neuroendocrine tumors and sarcoma
  • primary hyperparathyroidism and malignancy comprising nearly 90% of cases of hypercalcemia
  • an initial panel consisting of PTH, PTHrP, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D should be obtained
  • Lymphoma, a hypercalcemia due to 1,25-dihydroxyvitamin D mediated pathways, is implied by elevations in 1,25-dihydroxyvitamin D without concomitant elevations in 25-hydroxyvitamin D. In such cases, PTH is low and PTHrP undetectable
  • Treatment of hypercalcemia of malignancy is aimed at lowering the serum calcium concentration by targeting the underlying disease, specifically by inhibiting bone resorption, increasing urinary calcium excretion, and to a lesser extent by decreasing intestinal calcium absorption
  • mildly symptomatic disease
  • marked symptoms
  • hydration with isotonic fluid (if admitted), avoidance of thiazide diuretics, and a low-calcium diet
  • denosumab
  • Denosumab is an RANKL antibody that inhibits osteoclast maturation, activation, and function
  • Nathan Goodyear on 11 Sep 18
     
    hypercalcemia in cancer and treatments.
Nathan Goodyear

What does my patient's coronary artery calcium score mean? Combining information from t... - 0 views

www.ncbi.nlm.nih.gov/...PMC515311

calcium score heart disease coronary calcium score CVD cardiovascular disease

shared by Nathan Goodyear on 05 Oct 17 - No Cached
  • Nathan Goodyear on 05 Oct 17
     
    good review of the coronary calcium score and associated risk estimates.
herbnclay

How To Detox With Bentonite Clay | Bentonite Clay Detox - 0 views

www.herbnclay.com/...bentonite-clay-detox

calcium bentonite clay calcium Bentonite Clay detox detox clay powder detox drink

shared by herbnclay on 23 Mar 18 - No Cached
  • herbnclay on 23 Mar 18
     
    Bentonite clay is also known as Healing Clay which has a high concentration of minerals including silica, calcium, magnesium, sodium, iron, and potassium. You can even drink or eat calcium bentonite clay to receive all of its fantastic health benefits. Learn how to detox with bentonite clay.
Nathan Goodyear

ScienceDirect - Cell Calcium : Molecular mechanisms of calcium-dependent neurodegenerat... - 0 views

www.sciencedirect.com/...S0143416003001416

calcium glutamate glutamic acid excitotoxicity NMDA receptors

shared by Nathan Goodyear on 13 Dec 11 - No Cached
  • Nathan Goodyear on 13 Dec 11
     
    proposed mechanism of calcium involvement in excitotoxicity
Nathan Goodyear

Molecular mechanisms of calcium-dependent neurodeg... [Cell Calcium. 2003 Oct-Nov] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...12909079

calcium excitotoxicity

shared by Nathan Goodyear on 24 May 11 - No Cached
  • Key mediators of excitotoxic damage are Ca ions (Ca(2+))
  • Nathan Goodyear on 24 May 11
     
    Calcium involved in excitotoxicity
Nathan Goodyear

Vascular events in healthy older women receiving calcium supplementation: randomised co... - 0 views

www.bmj.com/...262.short

calcium cardiovascular events women postmenopausal

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Calcium supplementation in healthy postmenopausal women is associated with upward trends in cardiovascular event rates.
  • Nathan Goodyear on 15 Aug 11
     
    Calcium increases cardiovascular events in postmenopausal women.  Levels must be checked for any nutrient prior to starting therapy to ensure appropriate therapy.
Nathan Goodyear

Calcium supplements with or without vitamin D and ... [BMJ. 2011] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...21505219

calcium supplements cardiovascular events women MI myocardial infarction

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Calcium supplements with or without vitamin D modestly increase the risk of cardiovascular events
  • Nathan Goodyear on 15 Aug 11
     
    Nutrient levels must be evaluated prior to therapy.  Calcium supplementation increases cardiovascular events in women.
Nathan Goodyear

Effect of calcium supplements on risk of myocardial infarction and cardiovascular event... - 0 views

www.bmj.com/...bmj.c3691.full

calcium MI myocardial infarction cardiovascular disease

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Calcium supplements (without coadministered vitamin D) are associated with an increased risk of myocardial infarction.
  • Nathan Goodyear on 15 Aug 11
     
    Calcium can increase MI risk
Nathan Goodyear

Evidence that calcium supplements reduce fracture ... [Clin J Am Soc Nephrol. 2010] - P... - 0 views

www.ncbi.nlm.nih.gov/...20089500

calcium supplements fracture

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Until well designed, well executed, and well analyzed studies demonstrate a net benefit in morbidity, mortality, and cost, recommendations supporting the widespread use of calcium supplementation remain belief-based and not evidence-based
  • Nathan Goodyear on 15 Aug 11
     
    contrary to current thought, well designed studies that support Calcium supplementation to reduce fracture risk does not exist
Nathan Goodyear

Interpretation of the Coronary Artery Calcium Score in Combination with Conventional Ca... - 0 views

www.ncbi.nlm.nih.gov/...PMC3840900

calcium score coronary calcium score CVD heart health heart cardiovascular disease

shared by Nathan Goodyear on 05 Oct 17 - No Cached
  • Nathan Goodyear on 05 Oct 17
     
    A more recent article on the interpretation of the coronary calcium score.  Score alone must be taken in context with the individual.
herbnclay

Do You Know How Easy It Is To Transform Your Skin Using Clay? - 0 views

www.herbnclay.com/...easy-transform-skin-using-clay

calcium bentonite clay Calcium Bentonite Clay powder calcium Bentonite Clay detox

shared by herbnclay on 18 Jan 18 - No Cached
  • herbnclay on 18 Jan 18
     
    Clay has always been known for its versatility since ancient times, but right now, it is rage. Clay, especially Calcium Bentonite Clay has medical, therapeutic as well as cosmetic uses. Clay is very beneficial for detoxifying the body inside-out, as it also helps in aiding digestive problems.
Nathan Goodyear

Statins use and coronary artery plaque composition: Results from the International Mult... - 0 views

www.ncbi.nlm.nih.gov/...PMC4277888

statin statins plaque CAD coronary artery disease coronary artery calcium cardiovascular disease

shared by Nathan Goodyear on 17 Oct 17 - No Cached
  • Statin use is associated with an increased prevalence and extent of coronary plaques possessing calcium
  • As compared with individuals not taking statins, those taking statins possessed a significantly higher prevalence of obstructive CAD, as well as higher numbers of vessels with obstructive CAD
  • non-calcified plaques (NCP)
  • ...11 more annotations...
  • non-calcified (NCP), mixed (MP), or calcified (CP) plaque
  • statin use was each associated with a significantly higher prevalence of NCP, MP and CP
  • statin use was associated with increased presence of MP [odds ratio (OR) 1.46, 95% confidence interval (CI) 1.27–1.68, p < 0.001] and CP (OR 1.54, 95% CI 1.36–1.74, p < 0.001], but not NCP
  • statin use was associated with increasing numbers of coronary segments possessing MP and CP but not associated with increasing numbers of coronary segments possessing NCP
  • North America, Europe and Asia
  • A total of 6673 individuals (2413 on statin therapy and 4260 not on statin therapy) comprised the study population
  • we identified a strong association of statin use to coronary artery plaque features
  • statin use was associated with a differentially increased prevalence and extent of MP and CP
  • one potential unifying hypothesis is that rather than regression of coronary plaque, statins may contribute to the conversion of coronary plaque constituents, perhaps by conversion of NCP to plaque possessing calcium
  • Coronary computed tomographic angiography (CCTA)
  • Statin use was associated with a higher frequency of severe coronary artery stenoses as well as numbers of coronary vessels with obstructive CAD
  • Nathan Goodyear on 17 Oct 17
     
    Study finds statin therapy associated with increased coronary plaque with calcium.
Nathan Goodyear

Testosterone relaxes coronary arteries by opening the large-conductance, calcium-activa... - 0 views

ajpheart.physiology.org/...H1720.full

testosterone vasodilation DHT androgens calcium channels potassium channels

shared by Nathan Goodyear on 14 May 13 - No Cached
  • Nathan Goodyear on 14 May 13
     
    The androgens testosterone and DHT elicit vasodilation via calcium and potassium channel activation.  The vasodilatory effect of the androgens is through, in part, due to K activated Ca channels.  Also of note, DHT had the same effect and DHT cannot be aromatized to estrogen.
Nathan Goodyear

Calcium-D-glucarate - 0 views

www.thorne.com/...336.pdf

calcium-D-glucarate

shared by Nathan Goodyear on 05 Jan 13 - No Cached
  • Nathan Goodyear on 05 Jan 13
     
    great review on the benefits of calcium-D-glucarate. This article is well referenced.
Nathan Goodyear

Calcium: A target in the war on Alzheimer's disease - 0 views

dl-web.dropbox.com/...heimers_Disease_WhitePaper.pdf

Alzheimer's disease excitotoxicity neurotoxicity calcium

shared by Nathan Goodyear on 17 Feb 12 - No Cached
  • Nathan Goodyear on 17 Feb 12
     
    good discussion on Alzheimer's disease and the role of calcium
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