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Nathan Goodyear

QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY ... - 0 views

  • QUIN and kynurenic acid are mediators of neuronal dysfunction and nerve cell death in inflammatory diseases.
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    kynurenine pathway and neurological inflammation
Nathan Goodyear

Indoleamine 2,3 dioxygenase and quinolinic acid im... [Neuropathol Appl Neurobiol. 2005... - 0 views

  • kynurenine pathway is up-regulated in Alzheimer's disease (AD) brain
  • increases in the excitotoxin quinolinic acid (QUIN
  • indoleamine 2,3 dioxygenase (IDO) is abundant in AD compared with controls
  • ...1 more annotation...
  • QUIN may be involved in the complex and multifactorial cascade leading to neuro-degeneration in AD
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    immune system, inflammation, and brain come together to develop Alzheimer's disease
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unify... - 0 views

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    immunoexcitotoxicity and traumatic brain injury
Nathan Goodyear

Kynurenine Metabolites and Migraine: Experimental Studies and Therapeutic Perspectives - 0 views

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    Disordered tryptophan metabolism and migraine headaches.
Nathan Goodyear

Characterization of the Kynurenine Pathway in Human Neurons - 0 views

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    review of the kynurenine pathway 
Nathan Goodyear

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States - 0 views

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    review of studies looking at kyneurenine pathway and it's contribution to neurodegenerative disorders and mood disorders
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