http://www.diabetologia-journal.org/files/Narendran.pdf - 0 views
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Nathan Goodyear on 28 Oct 14Exercise is not just for calories out. Exercise increases growth hormone, IGF-1, glucagon-like peptide 1, IL-6, and IL-1ra. The effect is to GH increases beta islet cell mass and protects beta cell lines against IL-1beta, Interferon-gamma and TNF-alhpa induced apoptosis. IL-6 increased production increases GLP-1 and IL-1ra which counters IL-1beta. Interleukin-1beta induces islet cell apoptosis and thus IL-1ra counters this pro-inflammatory signal.