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Nathan Goodyear

ScienceDirect.com - Journal of Clinical Neuroscience - Testosterone improves motor func... - 0 views

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    Testosterone shown to improve motor skills in people suffering from Parkinson's disease.  
Nathan Goodyear

Estrogen, Menopause, and the Aging Brain: How Basic Neuroscience Can Inform Hormone The... - 0 views

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    Estrogen and the aging brain of a women.  Good review of the science of how estrogen effects the neurological system of the woman.
Nathan Goodyear

Frontiers | Performance enhancement at the cost of potential brain plasticity: neural r... - 0 views

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    Great article on the detriment of prescription stimulants for cognitive enhancement.  The authors describe an inverted "U" efficacy curve.
Nathan Goodyear

Low-Dose Naltrexone Reduces the Symptoms of Fibromyalgia - Stanford Systems Neuroscienc... - 0 views

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    low dose naltrexone shown to reduce pain in those with fibromyalgia.  This is a very small study, though with positive results.
Nathan Goodyear

3alpha-androstanediol, but not testoste... [Front Aging Neurosci. 2010] - PubMed - NCBI - 0 views

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    Now, this is a rat model, but 3 alpha androstanediol treatment restored cognitive function  greater than testosterone alone.
Nathan Goodyear

Fasting is neuroprotective following traumatic brain injury - Davis - 2008 - Journal of... - 0 views

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    short term fasting and ketosis provides neuroprotection and preserves mitochondria in animal TBI study.  This study found preventative effects of the ketones.
Nathan Goodyear

PsychiatryOnline | The Journal of Neuropsychiatry and Clinical Neurosciences | Can Trau... - 0 views

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    research, though limited, supports the hypothesis that TBI contributes to psychiatric disorders.
Nathan Goodyear

Figure 1 : The therapeutic potential of monoamine oxidase inhibitors : Nature... - 0 views

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    Monoamine oxidase A and B effect on dopamine metabolism
Nathan Goodyear

Estrogen, neuroinflammation and neuroprotection... [Neuroscience. 2006] - PubMed - NCBI - 0 views

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    Estrogen important in reducing neuroinflammation in Parkinson's disease in postmenopausal women?
Nathan Goodyear

BMC Neuroscience | Full text | In Vitro Assessment of Tobacco Smoke Toxicity at the BBB... - 0 views

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    Vitamin C and Vitamin E shown to protect against the many pro-oxidant effects of smoking
Nathan Goodyear

TO EAT OR TO SLEEP? OREXIN IN THE REGULATION OF FEEDING AND WAKEFULNESS - Annual Review... - 0 views

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    orexin: neuropeptide involved in regulation of sleep and eating.  Effected by stress. Suprise, suprise
Nathan Goodyear

PsychiatryOnline | The Journal of Neuropsychiatry and Clinical Neurosciences | The Neur... - 0 views

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    Understanding the neuroendocrine effects of TBI. This article discusses all hormonal effects as a result of TBI.
Nathan Goodyear

PsychiatryOnline | The Journal of Neuropsychiatry and Clinical Neurosciences | The Neur... - 0 views

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    TBI results in hormone disruption in 25-69% of those effected.  The major cause is a pituitary/neuro-endocrine effect.  This has been described since the early 20th century.
Nathan Goodyear

Increased extracellular levels of ascorbate in the striatum after middle cerebral arter... - 0 views

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    vitamin C released in the brain with an ischemic stroke.  Question: is this a way to provide scavenger for free radicals following a stroke?
Nathan Goodyear

Investigations on oxidativ... [Eur Arch Psychiatry Clin Neurosci. 1999] - PubMed - NCBI - 0 views

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    This study finds that AGE, advanced glycation end products, play a significant role in free radical generation and neurodegenerative disease. Quote: "... pharmacologoical approaches which break the vicious cycle of oxidative stress and neurodegeneration offer new opportunities for the treatment of AD. These approaches include AGE- inhibitors, antioxidants, and anti-inflammatory substances which prevent radical production." They focus on the pharmacological, how about the natural first?
Nathan Goodyear

Dihydrotestosterone may inhibit hypothalamo-pi... [Neurosci Lett. 2004] - PubMed - NCBI - 0 views

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    Mouse study finds that DHT metabolite provides negative feedback to HPA via 3beta androstaendiol.  What is interesting is that this signaling occurred through ER beta.  Androgen signaling processed through estrogen receptors.
Nathan Goodyear

Effect of lipoic acid consumption on oxidative... [Nutr Neurosci. 2014] - PubMed - NCBI - 0 views

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    1200 mg/day helps total antioxidant capacity in those with MS.
Nathan Goodyear

Progesterone enhances transthyretin expressio... [J Mol Neurosci. 2011] - PubMed - NCBI - 0 views

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    Postmenopausal cognitive decline is a common complaint.  Declining Estradiol and progesterone have been implicated, in part, to this cognitive decline.  This study finds that progesterone increases expression of Transthyretin, a protein that processes amyloid Beta protein.  This amyloid Beta protein is associated with damage found in Alzheimer's. 
Nathan Goodyear

In vitro neurotoxicity of methylisothiazolinone, ... [J Neurosci. 2002] - PubMed - NCBI - 0 views

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    Scary.  Common component of many OTC creams and ointments contain chemical, methylisothiazolinone that is neurotoxic.
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