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Nathan Goodyear

Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Re... - 0 views

pharmrev.aspetjournals.org/...162.full

orexin orexins sleep energy

shared by Nathan Goodyear on 02 Jan 13 - No Cached
  • Nathan Goodyear on 02 Jan 13
     
    great read on orexins!  Orexins play a role in feeding and in sleep/wake cycle. Orexins interact with the limbic system to play a role in reward.
Nathan Goodyear

ScienceDirect.com - Physiology & Behavior - Effects of leptin and orexin-A on food inta... - 0 views

www.sciencedirect.com/...S0031938400003413

leptin orexins appetite

shared by Nathan Goodyear on 28 May 13 - No Cached
  • orexin-A and orexin-B, localized in the posterior and lateral hypothalamic perifornical region were discovered in the rat brain and they increase food intake
  • Leptin, a protein encoded by an obesity gene, expressed in adipose tissue and released into the blood also affects food intake
  • Nathan Goodyear on 28 May 13
     
    Leptin and orexins regulate appetite regulate food intake.
Nathan Goodyear

Ghrelin-Induced Food Intake Is Mediated via the Orexin Pathway - 0 views

endo.endojournals.org/...1506.long

ghrelin orexin orexins appetite

shared by Nathan Goodyear on 28 May 13 - No Cached
  • Ghrelin, a peptide produced in the stomach and hypothalamus, stimulates feeding and GH secretion
  • Centrally administered ghrelin exerts an orexigenic activity through the neuropeptide Y (NPY)
  • though ghrelin is predominantly produced in endocrine cells of the stomach (17, 18), it is also synthesized in the hypothalamic arcuate nucleus (1, 19), a critical region for feeding
  • Nathan Goodyear on 28 May 13
     
    ghrelin stimulates feeding through orexin signaling.
Nathan Goodyear

ingentaconnect The Role of Orexin System in Antipsychotics Induced Weight Gain - 0 views

www.ingentaconnect.com/...art00002

orexin eating feeding weight-loss overweight obesity weight gain

shared by Nathan Goodyear on 02 Dec 11 - No Cached
  • The orexins modulate feeding behavior, some metabolic processes and arousal.
  • Nathan Goodyear on 02 Dec 11
     
    antipsychotics are associated with significant weight gain.  One proposed mechanism is the increased activation of orexin neurons in the areas of the brain (lateral hypothalamus and perifornical area) that regulate eating.  Amphetamines stimulate the same, just a drastically reduced levels
Nathan Goodyear

ScienceDirect - Cell Metabolism : Orexin Turns Up the Heat on Obesity - 0 views

www.sciencedirect.com/...S1550413111003536

orexin fat brown-fat thermogenesis weight-loss obesity

shared by Nathan Goodyear on 02 Dec 11 - No Cached
  • Nathan Goodyear on 02 Dec 11
     
    orexin, a neuropeptide, plays important role in brown fat differentiation.  Brown fat is important thermogenesis, producing heat from fat burning.
Nathan Goodyear

TO EAT OR TO SLEEP? OREXIN IN THE REGULATION OF FEEDING AND WAKEFULNESS - Annual Review... - 0 views

www.annualreviews.org/...annurev.neuro.24.1.429

orexin sleep narcolepsy eating feeding overweight weight-loss obesity

shared by Nathan Goodyear on 02 Dec 11 - No Cached
  • Nathan Goodyear on 02 Dec 11
     
    orexin: neuropeptide involved in regulation of sleep and eating.  Effected by stress. Suprise, suprise
Nathan Goodyear

Differential Activation of Orexin Neurons by Antipsychotic Drugs Associated with Weight... - 0 views

neuro.cjb.net/...6742.short

orexin weight gain overweight weight-loss obestiy

shared by Nathan Goodyear on 02 Dec 11 - No Cached
  • Nathan Goodyear on 02 Dec 11
     
    antipsychotic drugs shown to increase weight gain through increase in orexin activity.
Nathan Goodyear

Cell Metabolism - Orexin Is Required for Brown Adipose Tissue Development, Differentiat... - 0 views

www.cell.com/...S1550-4131(11)00340-8

orexin brown-fat weight-loss overweight obesity brown fat

shared by Nathan Goodyear on 01 Dec 11 - No Cached
  • Nathan Goodyear on 01 Dec 11
     
    orexin plays a role in weight gain through regulation of brown fat differentiation.  Low brown fat predisposes one to obesity.  Higher brown fat increases metabolism and thus increases fat burning capacity
Nathan Goodyear

Orexins in the Brain-Gut Axis: Endocrine Reviews: Vol 23, No 1 - 0 views

press.endocrine.org/...edrv.23.1.0454

Orexins appetite

shared by Nathan Goodyear on 25 Oct 14 - No Cached
  • Nathan Goodyear on 25 Oct 14
     
    Good review of Orexins.
Nathan Goodyear

Influence of ghrelin on food ... [Curr Opin Clin Nutr Metab Care. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17693746

Ghrelin orexin orexigenic peptide appetite

shared by Nathan Goodyear on 20 Aug 13 - No Cached
  • Nathan Goodyear on 20 Aug 13
     
    Ghrelin is an orexin that increases energy intake i.e. increases food intake.
Nathan Goodyear

Neuron - Activation of Central Orexin/Hypocretin Neurons by Dietary Amino Acids - 0 views

www.cell.com/...S0896627311007823

amino acids fatigue afternoon sugar orexin_hpocretin cells

shared by Nathan Goodyear on 01 Dec 11 - No Cached
  • Nathan Goodyear on 01 Dec 11
     
    non-essential amino acids are beneficial in preventing those afternoon energy slumps.  Sugar with its resultant insulin spike would make this worse.
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