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Sonny Cher

Get a Fulfilling and Explosive Sex Life - 1 views

My friend's wife told me that she cannot cope up with her husband's stamina when they are together. And she was worried that he might try to find another woman because she cannot satisfy him. So I...

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started by Sonny Cher on 20 Apr 11 no follow-up yet
Nathan Goodyear

http://onlinelibrary.wiley.com/store/10.1002/art.11105/asset/11105_ftp.pdf;jsessionid=4... - 0 views

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    good review of sex hormones and LUPUS; whether it is causative or not, sex hormones trends exist in LUPUS i.e. low DHEA in both sexes, low progesterone in women, and low Testosterone in women>men.
Rachna Clinic

Why Are You Searching Repudiated Sexual Ayurvedic Medico in Delhi? - 0 views

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    Sex is one of the most significant and pleasurable activities for men and women. Persons don't have sex only to conceive offspring. Why persons extend to have sex after having children? I have renowned numerous persons who relish sex even after the age of seventies so sex has no expiry time.
Nathan Goodyear

The permeability of the human red cell ... [Biochim Biophys Acta. 1994] - PubMed - NCBI - 0 views

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    sex hormones readily carried on human red blood cells.  Reason transdermal progesterone is picked up in saliva and not serum.  Sex hormones are lipophillic and blood is water soluble.
Nathan Goodyear

Individual diet has sex-dependent effects on vertebrate gut microbiota : Nature Communi... - 0 views

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    Sex difference of gut flora has different metabolic effects from the same diet.  Could it all begin in the get?  Are gut flora sexist?  Of course not, but this study highlights the sex difference of the gut flora and the gender different effects.
Nathan Goodyear

Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Co... - 0 views

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    somewhat flawed study in that they looked at serum sex hormones to evaluate men with gynecomastia compared to controls.  A better eval would have been of saliva or blood spot.  Free levels will show more subtle changes physiologically than will serum as to the sex hormones.  The study did find decreased sexual function in the men with gynecomastia--indicating hormone issues not picked up by the serum.
Nathan Goodyear

Endogenous Sex Hormones and Prostate Cancer: A Collaborative Analysis of 18 Prospective... - 0 views

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    a large collaborative analysis finds no association between ANY sex hormones and prostate cancer.  
Nathan Goodyear

Neuroprotection of Sex Steroids - 0 views

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    great article on sex hormones and neuroprotection.  This article summarizes the research on estrogen, progesterone, and aromatase activity in in vitro and in vivo studies.  Additionally, the study reviews the androgenic neuroprotection in men.  Who has said that hormones are not needed post menopausal again?  Maybe, that is the sign that they need the neuroprotective effect of hormones.
Nathan Goodyear

Sex steroids and cardiovascular disease Yeap BB - Asian J Androl - 0 views

  • Levels of SHBG are higher in older men, therefore levels of free T decline more steeply than total T as men's age increases.
  • calculations based on mass action equations may not reflect precisely free T measured using a reference method
  • free T declines more steeply with age than total T in both cross-sectional [35] and longitudinal studies, [36] as does free E2 in comparison to total E2
  • ...22 more annotations...
  • T may slow development of or progression of atherosclerosis by modulating effects on insulin resistance, inflammation, endothelial function, preclinical atherosclerosis or the vasculature.
  • these cross-sectional and longitudinal studies support a relationship between low circulating T with CIMT and higher E2 with its progression
  • lower levels of T are biomarkers for aortic vascular disease
  • circulating free T was negatively associated with the presence of AAA
  • luteinizing hormone (LH) was positively associated.
  • low levels of total or bioavailable T were associated with aortic atherosclerosis manifested as calcified deposits detected by radiography
  • Men with total or free T in the lowest quartile had increased adjusted ORs for PAD defined as ABI <0.90, as did men with free E2 in the highest quartile of values
  • The apparent association of SHBG with intermittent claudication reflects the correlation of total T with SHBG, while the contribution of E2 to risk of PAD remains unclear
  • men with total T in the lowest quartile of values (<11.7 nmol l−1 ) experienced an increased incidence of stroke or transient ischemic attack
  • lower total T with increased incidence of CVD events
  • cohort studies in mostly older men have supported the association of lower androgen levels with higher mortality
  • lower total or free T levels were associated with mortality in older men, but with discordant results for cause-specific mortality and for associations of E2
  • several large studies identifying lower endogenous levels of total or free T as independent predictors of all-cause or CVD-related deaths in middle-aged and older men
  • T exhibits anti-inflammatory effects, enhances flow-mediated brachial artery reactivity, and reduces arterial stiffness
  • Short-term T therapy had a beneficial effect on exercise-induced myocardial ischemia in middle-aged men with coronary artery disease or chronic stable angina, [95],[96],[97] and reduced angina frequency in older men with diabetes and coronary artery disease
  • T therapy resulted in an increase in treadmill test duration and time to ST segment depression
  • there are interventional studies supporting a protective effect of exogenous T against myocardial ischemia in men with coronary artery disease
  • employ conservative doses
    • Nathan Goodyear
       
      This dosing is 100 fold higher then peak production of a  young man at 20-22.
  • Observational studies indicate that lower levels of endogenous T in older men are associated with the presence of carotid atherosclerosis, aortic and peripheral vascular disease, and incidence of CVD events and mortality
  • Interventional studies have shown beneficial effects of exogenous T on vascular function and on exercise-induced myocardial ischemia in men with coronary artery disease
    • Nathan Goodyear
       
      the therapies employed in these studies were massively overdosed.
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    Nice review of all the sex hormones and their relationship to CVD in men.  
Nathan Goodyear

Sex differences in mitochondrial biogenesis determine neuronal death and survival in re... - 0 views

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    Differences in how mitochondria in men and women handle oxidative stress.  This gives insight to how sex hormones can play a role in neurodegeneration: whether protective or destructive.
Nathan Goodyear

Sex hormones and systemic lupus eryt... [Rheum Dis Clin North Am. 2000] - PubMed - NCBI - 0 views

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    older study and only the abstract.  However, sex hormones play role in inflammation and autoimmune disease.
Nathan Goodyear

Sex hormones in head and neck cancer: Current knowledge and perspectives Singh HP, Kuma... - 0 views

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    Sex hormones in head and neck cancer.  The jury is still out and probably follows other hormone sensitive cancers.  
Nathan Goodyear

Sex steroids and the thyroid. [Best Pract Res Clin Endocrinol Metab. 2009] - PubMed result - 0 views

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    sex hormones effect thyroid function
Nathan Goodyear

Ovarian function and disease acti... [Clin Exp Rheumatol. 2008 May-Jun] - PubMed - NCBI - 0 views

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    imbalanced sex hormones in women links to SLE. 
Nathan Goodyear

JAMA Network | JAMA | Sex Differences of Endogenous Sex Hormones and Risk of Type 2 Dia... - 0 views

  • lack of reliable data on levels of free hormones
  • endogenous levels of testosterone and SHBG each exhibit sex-dependent relations with risk of type 2 diabetes
  • high testosterone levels were associated with greater type 2 diabetes risk in women but lower risk in men
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  • the inverse association of SHBG was stronger in women than in men
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    No surprise, testosterone in men and women have different effects.  I just wrote a post on this.  Testosterone is positively associated with increased risk of diabetes in women, but inversely with men.  That is increased T in women equals increased Diabetes in women; contrast with increased T associated with decreased Diabetes in men.   But the interesting point is SHBG.  This study found a strong inverse association between SHBG with diabetes in women when compared to men.  Meaning: low SHBG is associated with an increased risk of type II Diabetes.  This is at the same time that testosterone is associated with an increased risk.
Nathan Goodyear

Evolving utility of sex h... [Curr Opin Endocrinol Diabetes Obes. 2012] - PubMed - NCBI - 0 views

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    SHBG plays more of a role than just sex hormone levels.  This study shows effect in metabolic syndrome, diabetes, and cardiovascular disease.
Nathan Goodyear

Clinical utility of sex hormone-binding globulin me... [Horm Res. 1996] - PubMed - NCBI - 0 views

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    Good discussion of SHBG on their effects of sex hormones; and vice versa.
Nathan Goodyear

Salivary Sex Hormone Measurement in a National, Population-Based Study of Older Adults - 0 views

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    Another study supports saliva hormone testing.  This study involved 2,722 individuals and tested estradiol, progesterone, DHEA and testosterone in men and women.  All of these are sex hormones.  Someone needs to tell the insurance companies that the overwhelming evidence supports saliva hormone testing.  But, that would mean they are even interested in the science.
vrocky

Men more likely to feel divine in lovemaking | www.vie2day.com - 0 views

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    England, have you ever feel why people shout out the Lord name during lovemaking, here is the Answer.a new study explain it as sex hormone
Nathan Goodyear

Early onset of hyperuricaemia and gout following treatment for female to male gender re... - 0 views

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    sex hormones play a role in the gout.  It appears that testosterone therapy increases uric acid levels and estradiol decreases uric acid levels.  Though, I question this based on the use of serum levels and thus inadequate assessment of aromatase activity.  Aromatase activity does not occur in the serum, it occurs in the tissue, thus saliva would be the best tool.
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