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review study of 263 studies finds no association between LDL and mortality in elderly.  In fact, the review found an inverse association between LDL and mortality i.e. increasing LDL associated with lower mortality in elderly.

Good discussion of the gut microbiome.  Age effects the gut bacteria balance.  The Firmicutes/Bacteroidetes ratio increases from young, to young adult, to the elderly in this study.  Is this simply a reflection of aging or is the a biomarker that can be changed through diet and targeted probiotics?

low vitamin D and PTH in black and white elderly associated with increased mortality; however, the black elderly have lower vitamin D levels in comparison to their white counterparts.  How does this play a in increased advanced disease?  I believe quite a bit.

Testosterone given to elderly men with low "serum" testosterone shown to increase IGF-1 and increased muscle growth and strength.  So, this study shows that testosterone in men, seems to increase HGH production and thus increase IGF-1 production.  This may be the mechanism by which testosterone promotes muscle growth and increase in strength in men.

Those men with higher estradiol levels found to have increased stroke risk.  This study only looked at elderly men > 71.  This should come as no surprise as E2 in men is know to increase inflammatory signaling.

transdermal DHT shown to increase DHT levels and shown to increase  androgenic effects in elderly men.

High salivary cortisol and decrease metabolism of cortisol (urinary) is associated with increased cognitive decline in the elderly.

30% caloric restriction significantly improved memory/cognitive function in elderly.

subclinical hypothyroidism is alarmingly high in elderly population--56%.

aromatase inhibition with arimidex, anastrozole, shown to be effective therapy to raise testosterone in elderly men with low T.

higher total cholesterol and LDL associated with better memory in the elderly population.  This was present in those without APOE4 allele

Even back in 1980, DHT metabolism was known.  Elderly men, 3alpha oxidoreductase is decreased resulting in decreased DHT to 3-alpha-diol.  This study discussed the DHT metabolite as inactive.  We now know that is not the case.

This study points to an association between a low-normal TSH and cognitive decline in the elderly.  An association is not causative, but functional hypothyroidism does result in cognitive impairment, so the association would logically fit.  The results of this study do as well.

Study found no significant effect of subclinical hypothyroidism on weight in the elderly.  However, higher free T4 levels were associated with lower baseline weight and weight loss in women. TSH and free T3 were not. associated.

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Study finds new difference in Testosterone benefits and/or side effects between men < 65 with low T and men > 65 with low T.

inflammation associated with decreased selenium in the elderly

This study found that high serum testosterone associated with a reduction of cardiovascular events in elderly men.  Studies have shown that low T is associated with increased cardiovascular mortality and in cardiovascular events, but this study takes it one step further: testosterone reduces those risks. 

Lavender essential oil for elderly shown to reduce falls.

exercise limits brain atrophy in the elderly.  Exercise provides neuroprotection.