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Nathan Goodyear

Access : Microbial ecology: Human gut microbes associated with obesity : Nature - 0 views

www.nature.com/...4441022a.html

firmicutes firmicutes_bacteroidetes bacteroidetes gut gut flora gut microbiome gut microbiota obesity

shared by Nathan Goodyear on 22 Sep 16 - No Cached
  • Nathan Goodyear on 22 Sep 16
     
    only abstract available: lower bacteroidetes associated with obesity.  This results in a higher F:B ratio.  Weight loss increased the Bacterodetes population.
Nathan Goodyear

The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age | BMC Micro... - 0 views

bmcmicrobiol.biomedcentral.com/...1471-2180-9-123

gut gut health gut flora gut microbiota firmicutes_bacteroidetes metabolism

shared by Nathan Goodyear on 09 Nov 16 - No Cached
  • C. leptum, C. coccoides, Bacteroides and Bifidobacterium represent the four dominant groups of the adult fecal microbiota
  • Lactobacilli Enterobacteriaceae, Desulfovibrio, Sporomusa, Atopobium as well as other bacterial groups including Clostridium clusters XI, XIVb, and XVIII
  • The Firmicutes/Bacteroidetes ratio undergoes an increase from birth to adulthood and is further altered with advanced age
  • Nathan Goodyear on 09 Nov 16
     
    good review/discussion of gut microbiota, including the firmicutes:bacteroidetes ratio.
Nathan Goodyear

Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat... - 0 views

press.endocrine.org/...jc.2016-1797

obesity gut gut flora gut microbiome gut microbiota butyrate firmicutes_bacteroidetes firmicutes bacteroidetes

shared by Nathan Goodyear on 22 Sep 16 - No Cached
  • Nathan Goodyear on 22 Sep 16
     
    gut bacteria differentiate obese versus non-obese.  Association found b/t firmicutes:bacteroidetes, increased Bacteroidetes, and Actinobacteria; in addition, acute, propionate, and butyrate (all medium chain fatty acids) were found to be associated with obesity.
Nathan Goodyear

BMC Microbiology | Full text | The Firmicutes / Bacteroidetes ratio of the human microb... - 0 views

www.biomedcentral.com/...123

gut flora gut microbiome gut microbiota firmicutes bacteroidetes firmicutes_bacteroidetes health gut microbiome

shared by Nathan Goodyear on 06 May 15 - No Cached
  • The microbiota of the large intestine plays an important role in host metabolism and maintenance of host health
  • Our results defining a standard adult profile, together with previous reports, showed that C. leptum, C. coccoides, Bacteroides and Bifidobacterium represent the four dominant groups of the adult fecal microbiota
  • Sub-dominant groups are Lactobacilli Enterobacteriaceae, Desulfovibrio, Sporomusa, Atopobium as well as other bacterial groups including Clostridium clusters XI, XIVb, and XVIII
  • ...12 more annotations...
  • In infant fecal microbiota, we observed Bifidobacterium as the dominant group
  • this observation is strongly related to diet, being enhanced by breast feeding
  • Significant higher numbers of Bifidobacterium were observed in infants versus adults and seniors
  • the gastrointestinal tract is first colonized by facultative anaerobes, such as E. coli
  • Strict anaerobes, such as Clostridium, colonize at later stages, as can be seen by the relatively low levels of C. leptum and C. coccoides in infants
  • diet change must be considered among the primary causes for such a shift of microbiota between infants and adults.
  • In the case of elderly subjects, our qPCR results indicated a significant increase in the counts of E. coli when compared to adults. This data is consistent with other publications indicating that elderly subjects harbor a different E. coli microbiota profile compared to younger adults
  • a number of authors reported a reduction in the numbers and diversity of many protective commensal anaerobes, such as Bacteroides and Bifidobacteria
  • The Firmicutes to Bacteroidetes ratio was already shown to be of significant relevance in signaling human gut microbiota status
  • Our measurements of the Firmicutes/Bacteroidetes ratio in adults obtained by our species-specific qPCR are in agreement with those obtained by Ley et al
  • Compared with young adults, the elderly have a different digestive physiology, characterized at a physiological level by a reduction in transit and of digestive secretions
  • The Firmicutes/Bacteroidetes ratio undergoes an increase from birth to adulthood and is further altered with advanced age
  • Nathan Goodyear on 06 May 15
     
    Good discussion of the gut microbiome.  Age effects the gut bacteria balance.  The Firmicutes/Bacteroidetes ratio increases from young, to young adult, to the elderly in this study.  Is this simply a reflection of aging or is the a biomarker that can be changed through diet and targeted probiotics?
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