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Nathan Goodyear

Aromatase and regulation of the estrogen-to... [Ann N Y Acad Sci. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24684533

aromatase aromatase activity vitamin D estrone E1 inflammation RA rheumatoid arthritis

shared by Nathan Goodyear on 07 Apr 14 - No Cached
  • Nathan Goodyear on 07 Apr 14
     
    Study looked at inflammatory markers in RA.  The authors point to high aromatase activity, low androgens, and elevated estrone in synovial fluid as an indicator of a link between aromatase activity and inflammation production through E1 production.  The authors also point to the 16 alpha metabolite pathway as pro-inflammatory as well.  One very interesting point made by the authors is that vitamin D down regulates aromatase activity.  In addition to NK-kappaB inhibition, this may be another mechanism by which vitamin D reduces inflammation.
Nathan Goodyear

Aromatase inhibitors for male infertility. [J Urol. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11792932

male infertility anastrozole arimidex aromatase inhibitor inhibition Testosterone:estradiol

shared by Nathan Goodyear on 26 Feb 12 - No Cached
  • Nathan Goodyear on 26 Feb 12
     
    aromatase inhibitor, arimidex (anastrozole), shown to be effective therapy in male infertility in those with high aromatase activity.  The effect was seen through improved Testosterone:Estradiol ratio through aromatase inhibition.
Nathan Goodyear

Estrogen Receptor-Related Receptor α Mediates Up-Regulation of Aromatase Expr... - 0 views

mend.endojournals.org/...1175.abstract

ER-alpha estrogen receptors aromatase prostate men male PGE2 hormone hormones

shared by Nathan Goodyear on 18 Sep 12 - No Cached
  • Nathan Goodyear on 18 Sep 12
     
    ER alpha increases aromatase expression in the prostate.  PGE2 increased the ER alpha receptor.  Vicious cycle in men.  Increased aromatase activity increases estrogen production which increases ER alpha (pro growth) and further aromatase activity.
Nathan Goodyear

Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity - 0 views

lup.sagepub.com/...635.short

aromatase testosterone estrogen estradiol IL-6 TNF-alpha IL-1 autoimmune disease inflammation inflammatory cytokines men hormones immune system

shared by Nathan Goodyear on 29 Apr 12 - No Cached
  • Nathan Goodyear on 29 Apr 12
     
    high conversion of testosterone to estrogen conversion in men is from increased aromatase activity.  Inflammatory cytokines, such as IL-6, TNF-alpha, has been shown to increase aromatase activity and at the same time increase IL-6 and other inflammatory cytokines is the result of increased aromatase activity.
Nathan Goodyear

Immunohistochemical evidence of the existence and localization of aromatase in human pr... - 0 views

onlinelibrary.wiley.com/...abstract

aromatase aromatase inhibitor prostate inflammation Testosterone Estradiol

shared by Nathan Goodyear on 15 May 12 - No Cached
  • Nathan Goodyear on 15 May 12
     
    aromatase activity is present in the prostate.  The conversion of Testosterone to Estradiol via aromatase activity has been shown to contribute to inflammation and prostate enlargement.
Nathan Goodyear

Red Versus White Wine as a Nutriti... [J Womens Health (Larchmt). 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22150098

wine red white aromatase inhibition premenopausal women breast cancer

shared by Nathan Goodyear on 06 Feb 12 - No Cached
  • Nathan Goodyear on 06 Feb 12
     
    red wine does appear to have health benefits over white wine through aromatase inhibition.  Aromatase inhibition reduces estrogen levels.  So, if the breast cancer risk is associated with elevated estrogen, then this would logically reduce the risk.  The exact amount is unknown, but aromatase inhibition is a treatment of those with breast CA.
Nathan Goodyear

Coadministration of anastrozole sustains therapeut... [J Sex Med. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24119010

Testosterone aromatase aromatase activity estradiol anastrazole aromatase inhibitor aromatase inhibitors aromatase inhibition men male hormone hormones

shared by Nathan Goodyear on 19 Feb 14 - No Cached
  • Nathan Goodyear on 19 Feb 14
     
    First, Testosterone pellets are not the way to go.  Historically, these will go the way of all the implantable contraceptive devices.  However, the conclusion of this study is good and confirms the benefit of anastrazole to inhibit aromatase activity and help to maintain Testosterone levels.
Nathan Goodyear

Aromatase and regulating the estrogen:androgen ratio in the prostate gland - 0 views

www.sciencedirect.com/...S0960076009002696

estrogen estradiol Testosterone T:E2 prostate cancer prostate BPH male men hormone hormones cancer health ER alpha ER beta aromatase activity aromatase

shared by Nathan Goodyear on 21 Aug 13 - No Cached
  • Nathan Goodyear on 21 Aug 13
     
    This article summarizes it all.  With age, Testosterone declines and estrogen production, through elevated aromatase activity, increases.  This results in a decline in the Testosterone:estradiol ratio.  This has been clearly implicated in both benign and disease states of the prostate.  The evidence points to aromatase activity and estrogen in the prostate to poor prostate health.  Additionally, this article points out the impact of ER alpha and ER beta on the translation of the message of Estrogen.
Nathan Goodyear

Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in... - 0 views

www.ncbi.nlm.nih.gov/...26950683

low T low Testosterone Testosterone prostate men male hormones PSA LUTS aromatase aromatase inhibition

shared by Nathan Goodyear on 08 Mar 16 - No Cached
  • Nathan Goodyear on 08 Mar 16
     
    study finds both Testosterone therapy and aromatase inhibition in men > 65 both increase Testosterone levels.  Increase in prostate size was only seen in the Testosterone only group; not in the AI group.  This implicates aromatase activity in the increase in prostate volume.  
Nathan Goodyear

Effects of aromatase inhibition vs. testosterone in older men with low testosterone: ra... - 0 views

www.ncbi.nlm.nih.gov/...26588809

low T low Testosterone Testosterone testosterone therapy aromatase inhibitors aromatase inhibition aromatase inhibitor aromatase men male hormones strength muscle mass muscle bone mineral density

shared by Nathan Goodyear on 07 Dec 15 - No Cached
  • Nathan Goodyear on 07 Dec 15
     
    No surprise that Testosterone therapy improves Testosterone levels in men with low T, but aromatase inhibition (AI) did as well.  In this study, only lean mass increased compared to Testosterone therapy and placebo.  Strength increased in both Testosterone and AI.
Nathan Goodyear

Stimulation of aromatase activity in bre... [Mol Cell Endocrinol. 1994] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7895904

inflammatory cytokines inflammation TNF-alpha aromatase activity estrone testosterone adipose fat tissue breast men women hormones androstenedione

shared by Nathan Goodyear on 29 Apr 12 - No Cached
  • Nathan Goodyear on 29 Apr 12
     
    inflammatory cytokine, TNF-alpha, increases aromatase activity.  This article discusses the increased production of estrone from androstenedione from aromatase activity in fat tissue in the breast.
Nathan Goodyear

Aromatase inhibitors in men: effects and therapeutic options - 0 views

www.ncbi.nlm.nih.gov/...PMC3143915

arimidex anastrozole aromatase inhibition inhibitor low T testosterone Testosterone:estradiol

shared by Nathan Goodyear on 26 Feb 12 - No Cached
  • Nathan Goodyear on 26 Feb 12
     
    Aromatase inhibition using arimidex, anastrozole, shown to be an effective therapy to raise testosterone levels in men with low T and high aromatase activity.
Nathan Goodyear

Benign prostatic hyperplasia (BPH) epithelial cell line BPH-1 induces aromatase express... - 0 views

joe.endocrinology-journals.org/...89.full

prostate BPH PGE2 inflammation men male hormone hormones aromatase estradiol estrone stroma

shared by Nathan Goodyear on 19 Sep 12 - No Cached
  • Nathan Goodyear on 19 Sep 12
     
    Increased aromatase activity is found in BPH.  PGE2 increases aromatase activity and thus increases Estradiol production in the stroma of the prostate.
Nathan Goodyear

Cognitive dysfunction in postmenopausal breast cancer patients on aromatase inhibitors,... - 0 views

informahealthcare.com/...era.11.112

breast cancer cognitive decline dysfunction women estradiol aromatase

shared by Nathan Goodyear on 10 Mar 14 - No Cached
  • Nathan Goodyear on 10 Mar 14
     
    Just the abstract here.  Declining estradiol production found to be associated with increased cognitive dysfunction or cognitive decline in those using aromatase inhibitor therapy.  Aromatase inhibition therapy is used to block Testosterone to Estradiol production in women with ER+ breast cancer.
Nathan Goodyear

Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testost... - 0 views

jcem.endojournals.org/...1174.full

aromatase inhibitor Testosterone estradiol estrogen men male hormon hormoens psa

shared by Nathan Goodyear on 23 Sep 13 - No Cached
  • Nathan Goodyear on 23 Sep 13
     
    Study looked at aromatase activity in androgen production in older men.  The study found that aromatase inhibition with arimidex increased Testosterone production.  PSA was also monitored and PSA increased in the smaller dose group versus the high dose group.
Nathan Goodyear

Oestrogens and prostate cancer - 0 views

erc.endocrinology-journals.org/...187.full.pdf

aromatase activity aromatase activity prostate cancer disease Testosterone estradiol male hormone hormones

shared by Nathan Goodyear on 24 Sep 13 - No Cached
  • Nathan Goodyear on 24 Sep 13
     
    Study confirms aromatase activity in the prostate itself. Systemic Testosterone and Estradiol evaluation (ie blood) will not necessarily reflect endogenous prostate aromatase activity.
Nathan Goodyear

Use of Aromatase Inhibitors in Large... [J Clin Endocrinol Metab. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25226294

aromatase aromatase inhibition aromatase inhibitor Man Boobs gynecomastia male hormones

shared by Nathan Goodyear on 17 Sep 14 - No Cached
  • Nathan Goodyear on 17 Sep 14
     
    aromatase inhibition therapy shown to reduce and/or eliminate man boobs in young boys with sertoli cell tumors.
Nathan Goodyear

ScienceDirect - The Journal of Urology : AROMATASE INHIBITORS FOR MALE INFERTILITY - 0 views

www.sciencedirect.com/...S0022534701690992

AROMATASE INHIBITORS MALE INFERTILITY Testosterone Estradiol hormone hormonal imbalance

shared by Nathan Goodyear on 10 Oct 11 - No Cached
  • Nathan Goodyear on 10 Oct 11
     
    aromatase inhibition in men to increase Testosterone:Estradiol ratio.  Men with infertility have a low Testosterone:Estradiol ratio.  Aromatase inhibitors inhibit Testosterone to Estradiol conversion
Nathan Goodyear

Hops (Humulus lupulus) inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Mali... - 0 views

www.ncbi.nlm.nih.gov/...PMC3252489

Hops estrogen aromatase inhibition aromatase inhibitor aromatase inhibitors aromatase hormone hormones

shared by Nathan Goodyear on 20 May 14 - No Cached
  • Nathan Goodyear on 20 May 14
     
    Hops inhibits aromatase activity.
Nathan Goodyear

Effect of hop (Humulus lupulus L.) flavono... [J Agric Food Chem. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16608212

Hops aromatase inhibitor aromatase inhibition aromatase inhibitors estrogen men male hormone hormones aromatase Humulus Lupulus

shared by Nathan Goodyear on 20 May 14 - No Cached
  • Nathan Goodyear on 20 May 14
     
    Hops is a natural aromatase inhibitor
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