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Nathan Goodyear

Sexual Function in Older Women After Oophorectomy : Obstetrics & Gynecology - 0 views

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    Here is my problems with "statistics".  The statement "No significant difference in the report of sexual ideation was found..."  If you are the one women that had decreased sexual function after having your ovaries removed: isn't it comforting to know you are not statistically significant.  Come on.  Some did, and that is enough and should be considered significant.  This is a permanent change to these woman's lives and marriage.
Nathan Goodyear

Seasonal variation of salivary testosterone in... [Physiol Behav. 2011] - PubMed - NCBI - 0 views

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    interesting study that showed that testosterone levels in men and women fluctuate seasonally.  The highest levels are found in the fall for both sexes, but lowest during the summer.  Interestingly, birth control eliminated these seasonal variations and resulted in a "flatter seasonal testosterone profile".   So, maybe mean cycle, but on a much different time scale?  Interesting thought.
Nathan Goodyear

Impact of Estrogen Receptor β on Gene Networks Regulated by Estrogen Receptor... - 0 views

  • ERβ acts as a tumor-suppressive protein
  • E2 may promote cell proliferation by inhibiting TGFβ production
  • ERβ modulated ERα regulation of TGFβ
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    Good discussion of the different effects of ER-alpha and ER-beta in breast cancer.  ER-beta inhibits growth in contrast to ER-alpha.
Nathan Goodyear

Mapping and Characterization of the Functional Domains Responsible for the Differential... - 0 views

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    different functions of PR-A and PR-B.
Nathan Goodyear

IL-1α and IL-1β Levels in Blood Serum and Saliva ... [Endocr Res. 2012] - Pub... - 0 views

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    Interleukins IL-1alpha and IL-1beta in saliva found to not be signifcantly different than serum.  Point: saliva is a good medium to evaluate many other biomarkers, inflammatory markers in this case.
Nathan Goodyear

Interaction between a peroxisome proliferator-activated receptor γ gene polym... - 0 views

  • uniform dietary recommendations may not be appropriate for all individuals
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    Peroxisome proliferator-activated receptor gamma plays an important role in obesity and fat generation.  In this study, they showed how the genetic expression of different PPAR gamma genotypes results in altered physiologic response to fat intake in humans.  The interaction between genetics and the environment.
Nathan Goodyear

The thyroid hormone, parathyroid hormone and vitamin D associated hypertension - 0 views

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    Good review of the hypertension (different) found in those with thyroid problems, parathyroid problems, and low vitamin D.
Nathan Goodyear

Effect of testosterone treatment on v... [J Cardiovasc Pharmacol. 1995] - PubMed - NCBI - 0 views

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    Granted a porcine model, but testosterone shown to have different effects in male versus female.
Nathan Goodyear

Potent Inhibition of Human Phosphodiesterase-5 by Icariin Derivatives - Journal of Natu... - 0 views

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    A natural phosphodiesterase 5 inhibitor would be nice.  This study looked at a lot of traditional herbal remedies to block phosphodiesterase 5 activity.  Only Epimedii herb with the active ingredient icariin worked.  Other preparations were shown to work, but via different mechanisms.  This is a review of studies looking at these herbal preparations.
Nathan Goodyear

The endocrinology of sexual arousal - 0 views

  • A number of age-related changes may be relevant: altered negative feedback of testosterone and hence less increase in luteinizing hormone (LH) with falling testosterone levels, increased sex hormone binding globulin (SHBG) and hence relatively reduced free testosterone and the likelihood of an age-related decline in testosterone receptor sensitivity
  • In the older male, the picture is complicated by various aging effects, including altered hypothalamo–pituitary feedback, increased testosterone binding and reduced receptor sensitivity
  • The neurophysiological basis of NPT is still disputed, but one plausible explanation is that REM sleep is associated with a ‘switching off’ of the noradrenergic cells in the locus coeruleus
  • ...1 more annotation...
  • the impact of testosterone on the emergence of sexual arousability is less clear
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    Good discussion of the arousal/sexual response differences between men and women from a physiological perspective.  
Nathan Goodyear

Cancer as a metabolic disease - 0 views

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    Dr. Seyfried provides a different perspective on cancer as a metabolic disease and not as a "genetic" disease as is the current dogma. Dr. Seyfried is well published on this topic and presents valid points to show that a ketogenic diet with intermittent fasting is anti-cancer.
Nathan Goodyear

Pre-receptor regulation of the androgen receptor - 0 views

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    Great read on the regulation of the androgen receptor by the different iso forms of 5-alpha reductase and HSD.
Nathan Goodyear

Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA an... - 0 views

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    Bisphenol A: review of the different biochemical effects of bisphenol A.
Nathan Goodyear

Thieme E-Journals - International Journal of Sports Medicine / Abstract - 0 views

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    competition versus recovery period in wrestling reveals different salivary hormone ratios. Competition results in low Testosterone to cortisol ratio versus the recovery phase which was found to be associated with a high testosterone to cortisol ratio.
Nathan Goodyear

Adiponectin oligomers as potential indicators of adipose tissue improvement in obese su... - 0 views

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    adiponectin is known to be associated with obesity.  This study finds that adiponectin levels in the serum and adipose tissue have different associations with obesity.  Also, there are two receptors for adiponectine: ADIPORs.  Serum adiponectin increases with improved cellular metabolism.
Nathan Goodyear

Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A... - 0 views

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    Different effects of estrogen on the brains of men and women.
wheelchairindia9

Karma Km 2500 Wheelchair - 0 views

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    Karma KM 2500 Small Wheel Wheelchair: Karma KM 2500 Small Wheel Wheelchair Specifications: Width 18" Front/Rear Wheels 6" to 14" Seat Width 47cm Seat Depth 40cm Overall Width 66cm Overall Collapsed Width 36cm Armrest Height 21cm Overall Length 90cm Seat Height 47cm Backrest Height 38cm Overall Height 86cm Weight 9.2 k.g. Karma KM 2500 Small Wheel Wheelchair Seat and Back: AEGIS Microbe Shield Approved by the FDA, EPA, EU, etc., bonded anti-microbial barrier upholstery protects from odor, staining and deterioration from bacteria, fungus and other microorganisms. It is a shield for your health. Karma KM 2500 Small Wheel Wheelchair Extended Armrest: By simulating the natural position of arms, the extended armrest design is ergonomic and creates bigger seating space. An Ultra lightweight wheelchair (9.2 kg) with a compact design for either attendant assisted or self propelling users. The use of aircraft-grade aluminium alloy and double cross brace provide this model with outstanding strength and durability. Karma Healthcare KM-2500 Premium Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 9.2 kg making it easy for anyone to lift into a vehicle. Backrest folds-down for easy transportation. Maximum user weight: 100 K.g. Aluminium frame. Fixed armrest/fixed footrest. Foldable frame via double cross bars. Comfortable & durable upholstery. Swing-away foot plates. Puncture proof tyres. Attendant cable brake. 14" flat-free rear wheels. Detachable and washable cushion. One Year Warranty. It folds down to take up virtually no space in the boot of a car. This amazingly light and compact transit wheelchair is ideal for outings and travelling. It comes with detachable and washable cushion. The wheel chair has attendant cable brake. It is made from aircraft-grade aluminium alloy fra
Nathan Goodyear

Will testosterone replacement therapy become a new treatment of chronic heart failure? ... - 0 views

  • TRT could improve significantly the exercise capacity of patients, compared with placebo
  • it could be seen that the effect of TRT on SBP and DBP was controversial
  • in men with congestive heart failure, testosterone reduced the Q-Td, whereas placebo had no effects
  • ...5 more annotations...
  • The MVC and PTmax were significantly improved in TRT patients but remained unchanged in the placebo group
  • handgrip strength improved significantly with testosterone treatment
  • According to EF assessed by echocardiography, no differences were observed between the patients who were prescribed testosterone and those who received placebo
  • There were no differences between the groups in circulating levels of NT pro-BNP, and inflammatory markers were unchanged, except for a decrease in TNF-α from baseline in the placebo group
  • Testosterone supplementation therapy appeared to be safe, and the subjects who accepted testosterone treatment did not appear any obvious adverse reactions.
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    Testosterone therapy in men with CHF found to increase exercise capacity, reduced the Q-T interval in men, improved muscle strength in men, and was found to be safe in meta-analysis.
Nathan Goodyear

Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in ... - 0 views

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    epidemiological study finds that telomere length inversely correlated with longevity, especially in those > 75.  The sex differences was significant beyond the age of 50, with women having longer telomere lengths.
Nathan Goodyear

urn:nbn:se:umu:diva-124842 : Training and hormones in physically active women : with an... - 0 views

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    Only abstract available: resistance training in first half of female cycle found to increase muscle mass and strength beyond that of the last 2 weeks.  No difference was found in the use of OCPs.
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