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Nathan Goodyear

Effect of resistance exercise on muscle steroidogenesis | Journal of Applied Physiology - 0 views

  • skeletal muscle cell cultures incubated with DHEA produced testosterone in a DHEA dose-dependent manner
  • Muscle joins a growing list of tissues found to be capable of steroidogenesis
  • testosterone appears to have a role in the maintenance of muscle mass in women, although the importance of this role has not yet been fully established.
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  • Circulating testosterone concentrations are generally elevated following a bout of resistance exercise in men (24, 31, 46, 52), whereas findings for the effect of resistance exercise on circulating testosterone in women are equivocal, with increases (10, 42) and no changes observed (22, 31)
  • swimming (51) and treadmill running (2) can significantly increase muscle testosterone concentrations in male and female rats
  • This upregulation of muscle testosterone in rats appears, at least in part, to be due to an increase in 3β-HSD and 17β-HSD type 1 expression
  • The primary finding in this study was that muscle steroidogenesis (i.e., testosterone production) in highly resistance-trained humans was not affected by an acute bout of heavy resistance exercise
  • A secondary finding was that the apparent molecular mass of 17β-HSD type 3 was increased following a single bout of heavy resistance exercise.
  • No differences were found for muscle testosterone or steroidogenic enzyme (17β-HSD type 3 and 3β-HSD types 1 and 2) concentrations between sexes or in response to resistance exercise
  • In conclusion, heavy resistance exercise did not induce changes in muscle steroidogenesis as measured by muscle concentrations of testosterone, 3β-HSD types 1 and 2, and 17β-HSD type 3 in highly resistance-trained young men and women.
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    Resistance exercise did not increase muscle concentrations of Testosterone in men or women.  The individuals in this study were actively training.  These were not sedentary individuals.
Nathan Goodyear

Testosterone physiology in resistance exercise an... [Sports Med. 2010] - PubMed - NCBI - 0 views

  • testosterone stimulates protein synthesis
  • promotion of muscle hypertrophy by testosterone
  • intracellular androgen receptor (AR)
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  • In general, testosterone concentration is elevated directly following heavy resistance exercise in men
  • Findings on the testosterone response in women are equivocal with both increases and no changes observed in response to a bout of heavy resistance exercise
  • Age also significantly affects circulating testosterone concentrations.
  • Aging beyond 35-40 years is associated with a 1-3% decline per year in circulating testosterone concentration in men
  • aging results in a reduced acute testosterone response to resistance exercise in men.
  • In women, circulating testosterone concentration also gradually declines until menopause, after which a drastic reduction is found.
  • acute increases in testosterone can be induced by resistance exercise
  • testosterone is an important modulator of muscle mass in both men and women
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    Resistance training to increase endogenous Testosterone production: more specific, the exercise must be high rep or as the authors call it--high volume.  To do this, the weight needs to be light.
Nathan Goodyear

http://www.biomed.cas.cz/physiolres/pdf/prepress/932627.pdf - 0 views

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    good discussion of the effects of resistance training on Testosterone and cortisol in obese men.  The literature is more more clear on the effects of resistance training on healthy men, but the evidence in obese men is less clear--likely due to the disrupted metabolism.
Nathan Goodyear

Effect of 12 weeks of periodized resistance training upon total plasma adiponectin conc... - 0 views

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    balance: exercise is no different. Cardio plus resistance training increases adiponectin over resistance training alone.
Nathan Goodyear

Is strength training associated with mortality benefits? A 15year cohort study of US ol... - 0 views

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    resistance training is not just for the young; new study finds that resistance training in those > 65 reduced all-cause mortality odds.
Nathan Goodyear

The activity of satellite cells and myonuclei following 8 weeks of ... - PubMed - NCBI - 0 views

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    Though, studies have shown that resistance training increases Testosterone production, this study finds that artificial suppression of Testosterone reduced myogenic response to 8 weeks of resistance training.
Nathan Goodyear

ACE - ProSource: July 2014 - Muscle Up! Evidence-based Solutions for Maximizing Muscle ... - 0 views

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    Online article reviewing the physiologic adaptation of muscle to resistance training.  The author used the evidence here to point to the most productive resistance training protocol--the RE effort.  The RE effort is the high repetition, lower weight regimen.  However, the RE to failure is critical to the success of RE.
Nathan Goodyear

Age-related hormonal adaptations, muscle circumference and strength development with 8w... - 0 views

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    Moderate resistance training program over 8 weeks associated with increased Testosterone production in young and middle age lean men.  Growth hormone was also increased in both groups.  ACTH and cortisol decreased in this lean men.  
Nathan Goodyear

Salivary cortisol and testosterone responses to resistance and plyometric exercise in 1... - 0 views

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    Study of 12-14 y/o boys found increased Testosterone after resistance training and plyometric exercise.  Cortisol did increase after plyometric, but not resistance exercise.
Nathan Goodyear

Changes in arterial distensibility and flow-mediated dilation after acute resistance vs... - 0 views

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    resistance exercise found to lower blood pressure.  Another feather in the cap of lifestyle intervention.  The blood pressure lowering effects with resistance training outperformed aerobic exercise.
Nathan Goodyear

Variations in urine excretion of steroid hormones after an acute session and after a 4-... - 0 views

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    4 week resistance training program found to increase androgens in urine; this suggests increased androgen production as a result of the resistance program
Nathan Goodyear

Nutritional regulation of muscle protein synthesis with resistance exercise: strategies... - 0 views

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    This study proposes that immediate post-resistance training protein helps to stimulate muscle growth. Recovery from training is just as important as the training itself.
Nathan Goodyear

Resistance Training to Momentary Muscular Failure Improves Cardiovascular Fitness in Hu... - 0 views

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    resistance training improves cardiovascular performance.
Nathan Goodyear

Thieme E-Journals - International Journal of Sports Medicine / Abstract - 0 views

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    Only abstract available here: compound resistance treaining in highly trained young men found to increase GH and Testosterone over isolation exercises. Those that trained > 2 years had significnt increase in Testosterone pre/post exercise compared to no statistical change in those traing < 2 years.
Nathan Goodyear

Crescent pyramid and drop-set systems do not promote greater strength gains, muscle hyp... - 0 views

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    no training benefit with pyramid and drop-set workouts compared to traditional resistance training.  The key is repeitition, proper technique and just doing it.
Nathan Goodyear

Resistance training restores muscle sex steroid hormone steroidogenesis in older men - 0 views

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    I like this study.  So many men, and women for that matter, focus on cardio for health and weight loss.  In men, low Testosterone is associated with aging as is weight.  This inverse relationship leads to the sarcopenic (belly, manboobs, and thin arms/legs) obesity so prevalent in older men today.  This study found that older men do have lower levels of enzymes and androgens from muscle biopsies as compared to younger men.  A 12 week resistance training regimen of only knee flexion and extension (simple) resulted in increased 3-beta-hydroxysteroid dehydrogenase and 17-beta-hydroxysteroid dehydrogenase.  
Nathan Goodyear

Effects of Resistance Training on Testosterone Metabolism in Younger and Older Men. - P... - 0 views

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    Resistance training increases Testosterone in younger and older men.  The effects in older men appears to involve more of a decreased metabolism.  
Nathan Goodyear

Healthcare | Free Full-Text | The Effects of Resistance Training on Physical Function a... - 0 views

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    Breast cancer survivors (BCS) exhibit decreased physical function and quality of life (QOL) following cancer treatments. Resistance training (RT) may elicit positive changes in physical and mental well-being. This study assessed 27 BCS, pre-and post-intervention (six months) on the following variables: muscular strength (via one repetition maximum (1RM) of chest press and leg extension), physical function (via the Continuous Scale-Physical Functional Performance test) and QOL (via the Short Form-36 survey). RT consisted of two days/week of ten exercises including two sets of 8-12 repetitions at 52%-69% of their 1RM. A repeated measures analysis of variance revealed BCS significantly (p &lt; 0.05) increased upper (71 ± 22 to 89 ± 22 kg) and lower body (74 ± 18 to 93 ± 24 kg) strength, total physical function (65.5 ± 12.1 to 73.6 ± 12.2 units) and the subcomponents of physical function: upper body strength (63.5 ± 16.3 to 71.2 ± 16.8 units), lower body strength (58.5 ± 14.9 to 68.6 ± 16.3 units), balance and coordination (66.5 ± 12.2 to 74.6 ± 11.6 units), and endurance (67.2 ± 12.0 to 75.0 ± 11.6 units). No changes were observed over time for subjective measures of physical function and QOL. Results showed RT could be an effective means to improve objective physical function in BCS. Further research is needed to clarify the effects of RT on subjective physical function and QOL.
Nathan Goodyear

Resistance training increases SHBG in overweight/obese, young men - 0 views

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    12 week study of obese  men in resistance training program finds increase in SHBG and resultant decrease in free Androgen index.  FAI is as a calculation of free Testosterone.  This is different in the studies in lean men which shows an increase in Testosterone. Here a different underlying metabolism is the result
Nathan Goodyear

Salivary testosterone and immunoglobulin A were increased by resistance training in adu... - 0 views

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    short resistance training program increases SIgA and Salivary Testosterone levels in adults with Downs Syndrome.
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