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Nathan Goodyear

Sexual Function in Older Women After Oophorectomy : Obstetrics & Gynecology - 0 views

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    Here is my problems with "statistics".  The statement "No significant difference in the report of sexual ideation was found..."  If you are the one women that had decreased sexual function after having your ovaries removed: isn't it comforting to know you are not statistically significant.  Come on.  Some did, and that is enough and should be considered significant.  This is a permanent change to these woman's lives and marriage.
Nathan Goodyear

Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-B... - 0 views

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    For most women, the practice of pre-menopausal, preventative removal of ovaries should be no more.  Evidence does not support a reduction in ovarian cancer; but, it does support an increased risk of depression, hyper lipidemia, cardiac arrhythmia, CAD, arthritis, asthma, COPD, and asthma.
Nathan Goodyear

Gene Expression of the Receptor for Growth-Hormone-Releasing Hormone Is Physiologically... - 0 views

  • weight gain was increased by oophorectomy (p < 0.005 vs. sham-operated
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    ovary removal results in increased weight gain
Nathan Goodyear

Increased risk of cognitive impairment or dementia in women who underwent oophorectomy ... - 0 views

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    Untold risk of early ovary removal appears to be cognitive decline and increased risk of dementia.  The earlier the age of removal, the more the increased risk of cognitive decline.  
Nathan Goodyear

Is Timing Everything? New Insights into Why the Effect of Estrogen Therapy on Memory Mi... - 0 views

  • Women who have an oophorectomy before the normal age at menopause show an increased risk for cognitive impairment or dementia later in life unless they are treated with estrogen until the normal age at menopause
  • SIRT1 has been implicated in the disruption of mitochondrial bioenergenetics in Alzheimer's disease and mild cognitive impairment
  • the increase in dementia observed with CEE/MPA rather than CEE alone suggests potential deleterious effects of MPA on brain function in older women
  • ...1 more annotation...
  • SIRT 1 as a potential mediator of the impact of E2
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    Early estrogen therapy in perimenopause and early menopause, with Estradiol, provides more health benefits than later therapy.  This article looked at Estrogen's effects on a woman's brain.  This likely has its origins in the change in estrogen receptors. The signal is not changing, but the reception of that signal is.  How else can one explain a different response to the same hormone dosage?
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