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Nathan Goodyear

Incidence of low-triiodothyronine syndrome in patients with septic shock - 0 views

www.ncbi.nlm.nih.gov/...PMC7853677

T4 TSH non-thyroidal illness syndrome septic shock sepsis T3

shared by Nathan Goodyear on 13 Apr 21 - No Cached
  • In the course of different disease states, the levels of T3, T4, and TSH decrease
  • euthyroid sick syndrome
  • low T3 can contribute to associated organ dysfunction
  • ...5 more annotations...
  • proportionally associated with disease severity and survival
  • nonthyroidal illness syndrome
  • Patients with persistent deterioration of hormone levels (T3, T4) during the study period had higher mortality than those who normalized the function of the thyroid axis
  • LT3S in patients with septic shock is part of the pathophysiology of this disease and/or an associated organ (endocrine-metabolic) failure and not just an adaptive phenomenon
  • substitution treatment with synthetic thyroid hormones could modify the hemodynamic symptoms of septic patients, contributing in part to the decrease in their morbidity and mortality
    • Nathan Goodyear
      Nathan Goodyear on 13 Apr 21
       
      Important statement
  • Nathan Goodyear on 13 Apr 21
     
    Septic shock and low T3
Nathan Goodyear

Chemotherapy for Patients with BRCA1 and BRCA2-Mutated Ovarian Cancer: Same or Differen... - 0 views

ascopubs.org/...EdBook_AM.2015.35.114

chemotherapy breast cancer BRCA platinum

shared by Nathan Goodyear on 14 May 21 - No Cached
  • Nathan Goodyear on 14 May 21
     
    BRCA and increased platinum sensitivity.
Nathan Goodyear

Activity of superoxide dismutase, catalase, glutathione peroxidase, and glutathione red... - 0 views

pubmed.ncbi.nlm.nih.gov/23625289

glutathione glutathione reductase SOD catalase gl cancer superoxide disumutase

shared by Nathan Goodyear on 07 Jun 23 - No Cached
  • Nathan Goodyear on 07 Jun 23
     
    "Glutathione reductase activity is lower in all colorectal carcinoma groups than in control, and a significant decrease in glutathione reductase activity was obtained between patients in tumor stage II and III compared to tumor stage IV." Same is see with SOD in study.
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