Group items tagged

stress shrinks brain.

Gut microbiome diversity is different in stressed mice and calm mice in animal study.  Authors propose intricate connection between gut:brain and possible evaluation and therapy in PTSD.

Mouse model finds that Cordyceps increased the interval to exhaustive exercise induced oxidative stress.  SOD, Cat, and GPx were increased in the low, intermediate, and high dose Cordyceps groups.  Oxidative stress markers MDA and 8-OHdG were lower in all groups

Endoplasmic reticulum stress and the implications in neurodegenerative disease through ROS and cell death.

high oxidative stress in autism will compromise detoxification. OR is it the other way around? Low Selenium is commonly found in those with autism.

Dr Jennifer Martinick shares reviews on negative effects of Stress. Stress can cause excessive Hair Loss.

Stress plays role in BDNF levels.  A decrease in BDNF is found in bipolar patients.  Stress will reduce neuroplasticity through a reduction in BDNF.

oxidative stress, mitochondrial death, and cancer 

Study finds that IV venofer increases oxidative stress and immune modulation to increase M1 but decreased NK cell expression. The study found that this was related to the effects of the IV Fe2+ (ferrous) form; whereas the oral delivered Fe3+ (ferric) form. More free Fe2+ was released as a result of venofer infusion that was independent of transferrin. This was associated with increased oxidative stress.

stress increases inflammation

acupuncture decreases HPA sympathetic drive.  Acupuncture calms the HPA axis and relieves stress.  Granted this is in a rat model.

Great review on how stress effects the neuroimmunoendocrine systems.

Very nice article on the thoughts currently involving stress, overactivity of the HPA axis and obesity.

Fantastic review of oxidative damage and the CNS.  This is a 2006 review of our understanding of how neurodegeneration occurs through oxidative stress and of course poor detoxification.

oxidative stress decreased type 1 deiodinase activity and thus T4 to T3 conversion, resulting in increased rT3 production.  Of interesting note, Alpha lipoic acid increased type I deiodinase activity and T4 to T3 conversion.

animal study finds vitamin C improves hypertension via renovascular source and oxidative stress.  The dosage was 150 mg/kg/day.  This would be equivalent to 10,800 grams daily for a 72 human.  But what about a 200 lb male or female?  That would be 13,650 grams of vitamin C daily.

astaxanthin reduced oxidative stress biomarker and inflammation in human study.

Omega 3 supplementation prevented oxidative stress in pregnancy.

Great review of the mechanisms of adaptogens on stress management

This study showed that "burnout" was associated with elevated salivary cortisol and this could explain part of the pathophysiology of CVD in these individuals.  This is a great article that shows that stress is a physiologic response and it kills