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Nathan Goodyear

PsychiatryOnline | American Journal of Psychiatry | CSF Norepinephrine Concentrations i... - 0 views

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    CSF norepinephrine levels found to be elevated in those with PTSD.  This is one of the few, if not only study, that has looked at epinephrine concentrations in PTSD.  Plasma norepinephrine levels were found to not be associated with PTSD.
Nathan Goodyear

SLC6A4 methylation modifies the effect of the number of traumatic events on risk for po... - 0 views

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    lower methylation status increases risk of PTSD.  Those with PTSD should be evaluated for methylation status.
Nathan Goodyear

Journal of Traumatic Stress, Volume 3, Number 3 - SpringerLink - 0 views

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    sleep disruption is a major symptom in those with PTSD.  There is no greater stress than combat.  The majority of research on PTSD is done on combat veterans
Nathan Goodyear

Low testosterone in a young combat veteran with dual diagnosis and ... - PubMed - NCBI - 0 views

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    Low T found in young combat veteran with PTSD and SI.  This is no surpass as there is significant HPA dysfunction in these men/women.  The overwhelming cortisol response and resultant PTSD will shut down endogenous Testosterone production.  I have seen this in several combat veterans.
Nathan Goodyear

PsychiatryOnline | American Journal of Psychiatry | Delayed-Onset Posttraumatic Stress ... - 0 views

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    delayed PTSD
Nathan Goodyear

Pharmacotherapy of PTSD: Premises, Principles, and Priorities - 0 views

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    Not so interested in the discussion on pharmacotherapy, but the discussing on the neuroendocrinology of PTSD.
Nathan Goodyear

Low Cortisol, High DHEA, and High Levels of Stimulated TNFα, and IL-6 in Wome... - 0 views

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    low cortisol pattern with elevated DHEA found in women with PTSD.  Additionally, elevated levels of TNF-alpha and IL-6 were found. Hormone evaluation was tested through saliva.
Nathan Goodyear

Posttraumatic Stress Disorder: Does the Gut Microbiome Hold the Key? - 0 views

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    Gut microbiome diversity is different in stressed mice and calm mice in animal study.  Authors propose intricate connection between gut:brain and possible evaluation and therapy in PTSD.
Nathan Goodyear

Concussive Brain Injury Enhances Fear Learning and Excitatory Processes in the Amygdala - 0 views

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    Link between TBI and PTSD.
Nathan Goodyear

A blunted cortisol awakening response and hippocampal atrophy in type 2 diabetes mellitus - 0 views

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    Individuals with type II DM, found to have blunted morning cortisol and decreased hippocampal volume.  The hippocampus is the focus of memory.  This is similar to what is found in PTSD.
Nathan Goodyear

Longitudinal Assessment of Mental Health Problems Among Active and Reserve Component So... - 0 views

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    PTSD in military deployed in combat is very high.  Estimated from between 20.3% to 42.4% of returning soldiers.  
Nathan Goodyear

Does stress damage the brain? [Biol Psychiatry. 1999] - PubMed - NCBI - 1 views

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    stress results in shrinkage of the hippocampus of the brain.  This would result in deficiency in serotonin and thus contribute to many of the symptoms found in those with PTSD.
Nathan Goodyear

Primary Psychiatry: The Neuroendocrinology of Posttraumatic Stress Disorder: New Direct... - 0 views

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    Neuroendocrinology of PTSD.
Nathan Goodyear

Hypocortisolism and increased glucocorticoid... [Biol Psychiatry. 2004] - PubMed - NCBI - 0 views

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    low cortisol and elevated LPS, IL-6, and TNF-alpha found in people with PTSD.
Nathan Goodyear

Emerald | Policing: An International Journal of Police Strategies & Management | Post-t... - 0 views

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    elevated cortisol levels found in moderate/severe PTSD in police officers.  Again, saliva testing was used for cortisol evaluation.
Nathan Goodyear

NCJRS Abstract - National Criminal Justice Reference Service - 0 views

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    PTSD is not just a short term issue.  The HPA dysfunction can persist long-term causing symptoms that extend far beyond the time of injury/healing.  What is interesting, is that the cortisol was evaluated with cortisol.  The new gold standard.
Nathan Goodyear

Low early morning plasma cortisol in posttraumatic stress disorder is associated with c... - 0 views

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    Low cortisol found in those with PTSD.  This study suggest the high ACTH/cortisol ratio is not due to enhanced peripheral sensitization to glucocorticoids.
Nathan Goodyear

Abuse-related posttraumatic stress dis... [Psychosom Med. 1995 Mar-Apr] - PubMed - NCBI - 0 views

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    chronic elevated norepinephrine and sympathetic activation foun din those individuals suffering from PTSD.
Nathan Goodyear

Elevated morning serum inte... [Psychoneuroendocrinology. 2007 Sep-Nov] - PubMed - NCBI - 0 views

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    elevated pm saliva cortisol and increased IL-6 is predictive of PTSD in children and adolescents.  
Nathan Goodyear

Biology of post-traumatic stress disorder ... [J Neuroendocrinol. 2008] - PubMed - NCBI - 0 views

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    appears that PTSD results in divergent catecholamine and cortisol levels as patients age.  The catecholamines (norepinephrine) will elevate and the cortisol will progressive decrease.  Additionally, this is revealed in salivary cortisol testing
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