Group items tagged alternative medicine - Dr. Goodyear

Evolving landscape of human epidermal growth factor receptor 2-positive breast cancer t... - 0 views

www.sciencedirect.com/...S0960977617300103

HER-2 breast cancer cancer herceptin Perjeta

shared by Nathan Goodyear on 06 Aug 18 - No Cached

15%–20%
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key mediator of cell growth, differentiation, and survival
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of higher histological grade and are more likely to invade axillary lymph nodes
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...15 more annotations...
shortened survival and an increased risk of disease recurrence and metastasis
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Currently, four HER2-directed agents are approved for the treatment of patients with HER2+ breast cancer: trastuzumab, pertuzumab, lapatinib, and ado-trastuzumab emtansine (T-DM1)
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biosimilars
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trastuzumab may provide greater benefit when administered concurrently with chemotherapy rather than after, and this has become the standard approach
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concurrent use of anthracyclines (ie, doxorubicin or epirubicin) and trastuzumab is not recommended because of an increased risk for cardiac toxicity
- Nathan Goodyear on 06 Aug 18
  
  avoid herceptin in conjuction with antracyclines i.e. doxorubicin
  
  <div class="cArrow"> </div><div class="cContentInner">avoid herceptin in conjuction with antracyclines i.e. doxorubicin</div>
  
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Sequential doxorubicin plus cyclophosphamide followed by concomitant paclitaxel or docetaxel and trastuzumab is recommended for most patients
- Nathan Goodyear on 06 Aug 18
  
  top recommended regimen combination
  
  <div class="cArrow"> </div><div class="cContentInner">top recommended regimen combination</div>
  
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Guidelines also recommend trastuzumab in combination with paclitaxel, docetaxel and carboplatin, or docetaxel and cyclophosphamide, particularly for patients with increased risk for cardiac toxicity or those with small (≤1 cm), node-negative HER2+ tumors
- Nathan Goodyear on 06 Aug 18
  
  good alternative in patients with increased risk of cardiac toxicity.
  
  <div class="cArrow"> </div><div class="cContentInner">good alternative in patients with increased risk of cardiac toxicity.</div>
  
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guidelines recommend up to 1 year of adjuvant trastuzumab
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Neoadjuvant chemotherapy with trastuzumab is associated with higher rates of pathologic complete response (pCR) than chemotherapy alone or in combination with lapatinib
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the combination of trastuzumab, lapatinib, and chemotherapy is not recommended because it failed to demonstrate noninferiority versus trastuzumab and chemotherapy in the adjuvant setting
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recommend the combination of trastuzumab, pertuzumab, and chemotherapy as neoadjuvant treatment for patients with locally advanced HER2+ breast cancer and for some patients (node-positive or tumor ≥2 cm) with early-stage disease
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neoadjuvant chemotherapy in combination with pertuzumab and trastuzumab reduced the risk of progression or death by 31% and recurrence or death by 40% versus trastuzumab alone
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Concurrent chemotherapy and HER2-directed therapy improves survival outcomes over chemotherapy alon
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dual inhibition of HER2 with trastuzumab and pertuzumab in combination with paclitaxel reduced the risk of death or progression by approximately 40% compared with concurrent trastuzumab and paclitaxel
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the combination of trastuzumab, pertuzumab, and taxane chemotherapy is the preferred first-line regimen
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Nathan Goodyear on 06 Aug 18

HER-2 + breast cancer = appx 15-20% of all breast cancers and is a marker of worse prognosis and an indication for targeted immunotherapy blockade.

<div class="cArrow"> </div><div class="cContentInner">HER-2 + breast cancer = appx 15-20% of all breast cancers and is a marker of worse prognosis and an indication for targeted immunotherapy blockade.</div>

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Turmeric | GreenMedInfo | Substance | Natural Medicine | Alternative Medicine - 0 views

www.greenmedinfo.com/...turmeric

natural medicine alternative Turmeric

shared by Nathan Goodyear on 13 Jun 11 - No Cached

Nathan Goodyear on 13 Jun 11

US National lIbrary of Medicine list of research on Turmeric

<div class="cArrow"> </div><div class="cContentInner">US National lIbrary of Medicine list of research on Turmeric</div>

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Curcumin | GreenMedInfo | Substance | Natural Medicine | Alternative Medicine - 0 views

www.greenmedinfo.com/...curcumin

natural medicine alternative curcumin turmeric

shared by Nathan Goodyear on 13 Jun 11 - No Cached

Nathan Goodyear on 13 Jun 11

US National Library of Medicine list of research on Curcumin

<div class="cArrow"> </div><div class="cContentInner">US National Library of Medicine list of research on Curcumin</div>

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http://69.164.208.4/files/Anti-inflammatory%20Properties%20of%20Curcumin,%20a%20Major%2... - 0 views

69.164.208.4/...0and%20Clinical%20Research.pdf

curcumin tumeric inflammation

shared by Nathan Goodyear on 07 Jun 16 - No Cached

Nathan Goodyear on 07 Jun 16

another review of the science on curcumin in treatment of disease. Pay careful attention to the pharmacokinetics portion of this article. Notice this is an "alternative Medicine" article, yet it is all science. The use of the word alternative is simply fear mongering.

<div class="cArrow"> </div><div class="cContentInner">another review of the science on curcumin in treatment of disease. Pay careful attention to the pharmacokinetics portion of this article. Notice this is an "alternative Medicine" article, yet it is all science. The use of the word alternative is simply fear mongering.</div>

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PLOS ONE: Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practiti... - 0 views

www.plosone.org/...journal.pone.0011414

IV vitamin C vitamin C intravenous alternative medicine complementary alternative

shared by Nathan Goodyear on 29 Sep 13 - No Cached

Nathan Goodyear on 29 Sep 13

Rare side effects of high dose vitamin C. Proven to be very safe compared to even labeled use of FDA approved drugs.

<div class="cArrow"> </div><div class="cContentInner">Rare side effects of high dose vitamin C. Proven to be very safe compared to even labeled use of FDA approved drugs.</div>

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BMC Complementary and Alternative Medicine | Full text | Frankincense essential oil pre... - 0 views

www.biomedcentral.com/...253

alternative alternative medicine essential oil oils Boswellia Frankincense pancreatic cancer cancer

shared by Nathan Goodyear on 01 Dec 13 - No Cached

Nathan Goodyear on 01 Dec 13

Boswellia sacra, Frankincense, proves to induce pancreatic cancer cell death in vitro.

<div class="cArrow"> </div><div class="cContentInner">Boswellia sacra, Frankincense, proves to induce pancreatic cancer cell death in vitro.</div>

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Vitamins E and C are safe across a broad range of intakes - 0 views

ajcn.nutrition.org/...736.long

vitamins vitamin E vitamin C alternative medicine

shared by Nathan Goodyear on 13 Jun 16 - No Cached

Nathan Goodyear on 13 Jun 16

high dose vitamin E and vitamin C are found to be safe. As always, the majority of these studies did not include pre-treatment vitamin assessment to ensure a metabolic need. To much of a good thing can be a bad thing. Also, higher dosing of vitamins approach a medicinal use and an associated increase in side effects.

<div class="cArrow"> </div><div class="cContentInner">high dose vitamin E and vitamin C are found to be safe. As always, the majority of these studies did not include pre-treatment vitamin assessment to ensure a metabolic need. To much of a good thing can be a bad thing. Also, higher dosing of vitamins approach a medicinal use and an associated increase in side effects.</div>

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Light Therapy More Effective Than Prozac in Patients With Major Depression | Natural Me... - 0 views

www.naturalmedicinejournal.com/...ozac-patients-major-depression

depression prozac SSRI natural medicine natural therapies alternative medicine

shared by Nathan Goodyear on 15 Apr 16 - No Cached

Nathan Goodyear on 15 Apr 16

new study finds that light therapy therapy for major depression outperformed prozac therapy. This study was short at only 8 weeks.

<div class="cArrow"> </div><div class="cContentInner">new study finds that light therapy therapy for major depression outperformed prozac therapy. This study was short at only 8 weeks.</div>

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Curcumin attenuates the development of allergic airway inflammation and hyper-responsiv... - 0 views

www.greenmedinfo.com/...ation-and-hyper-responsiveness

curcumin inflammtion airway allergy allergies NF-KappaB asthma

shared by Nathan Goodyear on 19 Jan 12 - No Cached

Nathan Goodyear on 19 Jan 12

curcumin shown to inhibit allergic airway inflammation, through NF-kappaB inhibition. This has implications in asthma flares.

<div class="cArrow"> </div><div class="cContentInner">curcumin shown to inhibit allergic airway inflammation, through NF-kappaB inhibition. This has implications in asthma flares.</div>

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Curcumin works synergistically with paclitaxel to inhibit breast cancer in a mouse mode... - 0 views

www.greenmedinfo.com/...ibit-breast-cancer-mouse-model

curcumin NF-KappaB inflammation breast cancer CA

shared by Nathan Goodyear on 19 Jan 12 - No Cached

Nathan Goodyear on 19 Jan 12

curcumin shown to augment paclitaxel in breast cancer treatment. Specifically, NF-kappaB inhibition resulted in reduction in tumor size, decreased tumor cell proliferation, increased apoptosis, and decreased MM-9.

<div class="cArrow"> </div><div class="cContentInner">curcumin shown to augment paclitaxel in breast cancer treatment. Specifically, NF-kappaB inhibition resulted in reduction in tumor size, decreased tumor cell proliferation, increased apoptosis, and decreased MM-9.</div>

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Astaxanthin: A Review of the Literature | Natural Medicine Journal - 0 views

naturalmedicinejournal.com/...astaxanthin-review-literature

astaxanthin natural alternative medicine natural medicine

shared by Nathan Goodyear on 25 Sep 15 - No Cached

Nathan Goodyear on 25 Sep 15

Nice review on astaxanthin.

<div class="cArrow"> </div><div class="cContentInner">Nice review on astaxanthin.</div>

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Franken-Thyroxine Making Your Thyroid Condition Worse? | GreenMedInfo | Blog entry | Na... - 0 views

www.greenmedinfo.com/...g-your-thyroid-condition-worse

thyroid synthroid bioidentical Thyroxine hormone

shared by Nathan Goodyear on 01 Aug 11 - No Cached

Nathan Goodyear on 01 Aug 11

synthroid is not biodentical Thyroxine (thyroid) hormone

<div class="cArrow"> </div><div class="cContentInner">synthroid is not biodentical Thyroxine (thyroid) hormone</div>

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The risks associated with mammography screening may be approximately five times higher ... - 0 views

www.greenmedinfo.com/...ve-times-higher-previously-ass

mammogram risks risk radiation breast cancer

shared by Nathan Goodyear on 21 Oct 11 - No Cached

Nathan Goodyear on 21 Oct 11

risks associated with mammogram are approximately 5 X higher than previously reported

<div class="cArrow"> </div><div class="cContentInner">risks associated with mammogram are approximately 5 X higher than previously reported</div>

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Efficacy and Safety of Curcumin in Major Depre... [Phytother Res. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23832433

curcumin tumeric depression SSRI fluoxetine natural medicine natural alternative medicine complementary medicine

shared by Nathan Goodyear on 01 Dec 15 - No Cached

Nathan Goodyear on 01 Dec 15

curcumin found to be statistically similar to fluoxetine in depression; In combination there is an adjuvant effect to increase the efficacy.

<div class="cArrow"> </div><div class="cContentInner">curcumin found to be statistically similar to fluoxetine in depression; In combination there is an adjuvant effect to increase the efficacy.</div>

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JAMA Network | JAMA Pediatrics | Association of Early Exposure of Probiotics and Islet ... - 0 views

archpedi.jamanetwork.com/article.aspx

probiotics probiotic alternative medicine natural medicine diabetes complementary medicine

shared by Nathan Goodyear on 17 Dec 15 - No Cached

Nathan Goodyear on 17 Dec 15

early probiotic supplementation decreased autoimmune Diabetes in children in study.

<div class="cArrow"> </div><div class="cContentInner">early probiotic supplementation decreased autoimmune Diabetes in children in study.</div>

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Science Magazine: Sign In - 0 views

www.sciencemag.org/...science.aaa5004.full.pdf

vitamin C cancer natural medicine alternative medicine complementary medicine

shared by Nathan Goodyear on 18 Dec 15 - No Cached

Nathan Goodyear on 18 Dec 15

new study supports what we already know: high dose vitamin C kills colorectal cancer in cell culture.

<div class="cArrow"> </div><div class="cContentInner">new study supports what we already know: high dose vitamin C kills colorectal cancer in cell culture.</div>

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Effect of Probiotics on Blood Pressure - 0 views

hyper.ahajournals.org/...RTENSIONAHA.114.03469.abstract

probiotics blood pressure blood pressure natural alternative alternative medicine

shared by Nathan Goodyear on 23 Jul 14 - No Cached

Nathan Goodyear on 23 Jul 14

Isn't it amazing how "alternative" medical therapies are proven time and time again with science? This study finds modes improvement in blood pressure with probiotics greater than 100 million CFU for more than 8 weeks. The therapy provided a modest decrease in B/P, but a decrease none the less.

<div class="cArrow"> </div><div class="cContentInner">Isn't it amazing how "alternative" medical therapies are proven time and time again with science? This study finds modes improvement in blood pressure with probiotics greater than 100 million CFU for more than 8 weeks. The therapy provided a modest decrease in B/P, but a decrease none the less.</div>

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BMC Complementary and Alternative Medicine | Full text | An open label pilot study to e... - 0 views

www.biomedcentral.com/...475

black spanish radish radish alternative medicine nutrition detoxification

shared by Nathan Goodyear on 03 Feb 15 - No Cached

Nathan Goodyear on 03 Feb 15

Black Spanish radish found to up regulate phase I/II liver detoxification with tylenol exposure. Now, this was sponsored by a maker of a herbal product so that would include some potential bias.

<div class="cArrow"> </div><div class="cContentInner">Black Spanish radish found to up regulate phase I/II liver detoxification with tylenol exposure. Now, this was sponsored by a maker of a herbal product so that would include some potential bias. </div>

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Nutraceuticals in Prostate Disease: The Urologist's Role - 0 views

Nathan Goodyear on 25 Sep 15

nice review of natural therapies on the prostate.

<div class="cArrow"> </div><div class="cContentInner">nice review of natural therapies on the prostate.</div>

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Quercetin in men with category III chronic prostatitis: a preliminary prospective, doub... - 0 views

www.ncbi.nlm.nih.gov/...10604689

quercetin bioflavonoids prostatitis prostate disease natural medicine alternative medicine