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Matti Narkia

n-3 Fatty acids and gene expression -- Deckelbaum et al. 83 (6): S1520 -- American Jour... - 0 views

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    n-3 fatty acids and gene expression.
    Deckelbaum RJ, Worgall TS, Seo T.
    Am J Clin Nutr. 2006 Jun;83(6 Suppl):1520S-1525S. Review. Erratum in: Am J Clin Nutr. 2006 Oct;84(4):949.
    PMID: 16841862

    Accumulating evidence in both humans and animal models clearly indicates that a group of very-long-chain polyunsaturated fatty acids, the n-3 fatty acids (or omega-3), have distinct and important bioactive properties compared with other groups of fatty acids. n-3 Fatty acids are known to reduce many risk factors associated with several diseases, such as cardiovascular diseases, diabetes, and cancer. The mechanisms whereby n-3 fatty acids affect gene expression are complex and involve multiple processes. As examples, n-3 fatty acids regulate 2 groups of transcription factors, such as sterol-regulatory-element binding proteins and peroxisome proliferator-activated receptors, that are critical for modulating the expression of genes controlling both systemic and tissue-specific lipid homeostasis. Modulation of specific genes by n-3 fatty acids and cross-talk between these genes are responsible for many effects of n-3 fatty acids.
Matti Narkia

A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors an... - 0 views

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    A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
    Mente A, de Koning L, Shannon HS, Anand SS.
    Arch Intern Med. 2009 Apr 13;169(7):659-69. Review.
    PMID: 19364995

    Conclusions The evidence supports a valid association of a limited number of dietary factors and dietary patterns with CHD. Future evaluation of dietary patterns, including their nutrient and food components, in cohort studies and randomized trials is recommended
Matti Narkia

A comparison of egg consumption with other modifiable coronary heart disease lifestyle ... - 0 views

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    A comparison of egg consumption with other modifiable coronary heart disease lifestyle risk factors: a relative risk apportionment study.
    Barraj L, Tran N, Mink P.
    Risk Anal. 2009 Mar;29(3):401-15. Epub 2008 Nov 4.
    PMID: 19000074
    DOI: 10.1111/j.1539-6924.2008.01149.x

    Guidelines from the American Heart Association (AHA) recommend that healthy adults limit their intake of dietary cholesterol to less than 300 mg per day. Since a large egg contains about 71% of that amount, the AHA recommends restricting egg consumption unless dietary cholesterol intakes from other sources are limited. We applied a risk apportionment approach to estimate the contribution of egg consumption and other modifiable lifestyle risk factors (e.g., smoking, poor diet, minimal exercise, and alcohol intake) to coronary heart disease (CHD) risk at the population level. Specifically, we categorized the U.S. adult population ages 25+ into distinct risk groups based on the prevalence of modifiable lifestyle risk factors and applied an apportionment model, typically used to assess risk contribution at the individual level, to estimate the contribution of egg intake to CHD risk. Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for <1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.
Matti Narkia

Low vitamin D linked with CVD risk factors in teens - theheart.org - 0 views

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    "March 18, 2009 | Marlene Busko

    Palm Harbor, FL - In a large study of adolescents, low serum levels of 25-dihydroxyvitamin D (25[OH]D) strongly predicted prevalence of hypertension, hyperglycemia, and metabolic syndrome [1]. The findings were reported at the AHA 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

    Adolescents with vitamin-D levels in the lowest quartile were almost four times more likely to have metabolic syndrome than those with vitamin-D levels in the highest quartile. "I think that is quite alarming," lead author Dr Jared P Reis (Johns Hopkins Medical Institutions, Baltimore, MD) said in an AHA podcast issued to the media."
Matti Narkia

Effects of a short-term intervention with a paleolithic diet in healthy volunteers - Eu... - 0 views

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    Effects of a short-term intervention with a paleolithic diet in healthy volunteers.
    Osterdahl M, Kocturk T, Koochek A, Wändell PE.
    Eur J Clin Nutr. 2008 May;62(5):682-5. Epub 2007 May 16.
    PMID: 17522610

    Conclusion: This short-term intervention showed some favourable effects by the diet, but further studies, including control group, are needed.
Matti Narkia

Environmental risk factors for autism: Do they help cause de novo genetic mutations tha... - 0 views

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    Environmental risk factors for autism: Do they help cause de novo genetic mutations that contribute to the disorder?
    Kinney DK, Barch DH, Chayka B, Napoleon S, Munir KM.
    Med Hypotheses. 2009 Aug 20. [Epub ahead of print]
    PMID: 19699591
Matti Narkia

Fatigue fractures in military conscripts : A study on risk factors, diagnostics and lon... - 0 views

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    Fatigue fractures in military conscripts : A study on risk factors, diagnostics and long-term consequences
    Ruohola, Juha-Petri
    University of Helsinki, Faculty of Medicine, Institute of Clinical Medicine, Orthopaedics and Traumatology, Helsinki University Central Hospital
    Centre of Military Medicine, Helsinki
    2007-03-09
    Doctoral dissertation (article-based)

    It seems likely that low vitamin D levels are related to fatigue fractures, and that an increasing trend exists between TRACP-5b bone resorption marker elevation and fatigue fracture incidence. Though seldom detected by plain radiography, fatigue fractures often underlie unclear lower leg stress-related pain occurring in the distal parts of the tibia. Femoral neck fatigue fractures, when displaced, lead to long-term morbidity in a high percentage of patients, whereas, when non-displaced, they do not predispose patients to subsequent adverse complications. Importantly, an educational intervention can diminish the incidence of fracture displacement by enhancing awareness and providing instructions for earlier diagnosis of fatigue fractures
Matti Narkia

Prevalence and Associations of 25-Hydroxyvitamin D Deficiency in US Children: NHANES 20... - 0 views

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    Prevalence and Associations of 25-Hydroxyvitamin D Deficiency in US Children: NHANES 2001-2004.
    Kumar J, Muntner P, Kaskel FJ, Hailpern SM, Melamed ML.
    Pediatrics. 2009 Aug 3. [Epub ahead of print]
    PMID: 19661054

    CONCLUSIONS: 25(OH)D deficiency is common in the general US pediatric population and is associated with adverse cardiovascular risks.
Matti Narkia

Factors that Influence the Cutaneous Synthesis and Dietary Sources of Vitamin D - 0 views

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    Factors that influence the cutaneous synthesis and dietary sources of vitamin D.
    Chen TC, Chimeh F, Lu Z, Mathieu J, Person KS, Zhang A, Kohn N, Martinello S, Berkowitz R, Holick MF.
    Arch Biochem Biophys. 2007 Apr 15;460(2):213-7. Epub 2007 Jan 8.
    PMID: 17254541
    doi: 10.1016/j.abb.2006.12.017

    Vitamin D is rare in food. Among the vitamin D-rich food, oily fish are considered to be one of the best sources. Therefore, we analyzed the vitamin D content in several commonly consumed oily and non-oily fish. The data showed that farmed salmon had a mean content of vitamin D that was ~25% of the mean content found in wild caught salmon from Alaska, and that vitamin D2 was found in farmed salmon, but not in wild caught salmon. The results provide useful global guidelines for obtaining sufficient vitamin D3 by cutaneous synthesis and from dietary intake to prevent vitamin D deficiency and its health consequences.ensuing illness, especially, bone fractures in the elderly.
Matti Narkia

Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascu... - 0 views

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    Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers.
    Zittermann A, Frisch S, Berthold HK, Götting C, Kuhn J, Kleesiek K, Stehle P, Koertke H, Koerfer R.
    Am J Clin Nutr. 2009 May;89(5):1321-7. Epub 2009 Mar 25.
    PMID: 19321573
Matti Narkia

Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the e... - 0 views

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    Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation.
    Schambach F, Schupp M, Lazar MA, Reiner SL.
    Eur J Immunol. 2007 Sep;37(9):2396-9.
    PMID: 17694576
    DOI: 10.1002/eji.200737621
Matti Narkia

A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Norma... - 0 views

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    The results suggest that a short-term ketogenic diet does not have a deleterious effect on CVD risk profile and may improve the lipid disorders characteristic of atherogenic dyslipidemia.

    A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men.
    Sharman MJ, Kraemer WJ, Love DM, Avery NG, Gómez AL, Scheett TP, Volek JS.
    J Nutr. 2002 Jul;132(7):1879-85.
    PMID: 12097663
Matti Narkia

Two eggs a day 'does not increase cholesterol levels' - MedWire News - Consumer Health - 0 views

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    MedWire News: Eating two eggs a day, as part of an energy-restricted weight-loss diet, does not increase levels of 'bad' or total cholesterol, results of a UK study show.
Matti Narkia

Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or d... - 0 views

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    Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation.
    Agren JJ, Väisänen S, Hänninen O, Muller AD, Hornstra G.
    Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):419-21.
    PMID: 9430389
    doi:10.1016/S0952-3278(97)90421-X    
Matti Narkia

A comparison of egg consumption with other modifiable coronary heart disease lifestyle ... - 0 views

  •  
    A comparison of egg consumption with other modifiable coronary heart disease lifestyle risk factors: a relative risk apportionment study.
    Barraj L, Tran N, Mink P.
    Risk Anal. 2009 Mar;29(3):401-15. Epub 2008 Nov 4.
    PMID: 19000074
    DOI: 10.1111/j.1539-6924.2008.01149.x

    Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for <1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.
Matti Narkia

Environmental factors that influence the cutaneous production of vitamin D -- Holick 61... - 0 views

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    Environmental factors that influence the cutaneous production of vitamin D.
    Holick MF.
    Am J Clin Nutr. 1995 Mar;61(3 Suppl):638S-645S. Review.
    PMID: 7879731
Matti Narkia

Study Links Diet Soft Drinks With Cardiac Risk | LiveScience - 0 views

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    Drinking more than one soda a day -- even if it's the sugar-free diet kind -- is associated with an increased incidence of metabolic syndrome, a cluster of risk factors linked to the development of diabetes and cardiovascular disease, a study finds
Matti Narkia

Sham vs. Wham: The Health Insider: The Beverage Yerba Maté May Have Ties to H... - 0 views

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    "Maté consumption plays a significant and independent role in the development of upper aeodigestive tract cancers," and "Maté drinking should be considered one of the risk factors for cancer of the neck and head."
Matti Narkia

Factors that influence the cutaneous synthesis and dietary sources of vitamin D - Scien... - 0 views

  •  
    Chen TC, Chimeh F, Lu Z, Mathieu J, Person KS, Zhang A, Kohn N, Martinello S, Berkowitz R, Holick MF.
    Factors that influence the cutaneous synthesis and dietary sources of vitamin D.
    Arch Biochem Biophys. 2007 Apr 15;460(2):213-7. Epub 2007 Jan 8.
    PMI
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