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Matti Narkia

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views

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    Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n
Matti Narkia

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

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    Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105
Matti Narkia

Dietary supplementation with white button mushroom enhances natural killer cell activit... - 0 views

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    Dietary supplementation with white button mushroom enhances natural killer cell activity in C57BL/6 mice. Wu D, Pae M, Ren Z, Guo Z, Smith D, Meydani SN. J Nutr. 2007 Jun;137(6):1472-7. PMID: 17513409
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits...[Nutr Cancer. 2008] - PubMed Result - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. PMID: 19005974
Matti Narkia

The effects of whole mushrooms during inflammation. - BioMed Central | Full text | - 0 views

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    The effects of whole mushrooms during inflammation. Yu S, Weaver V, Martin K, Cantorna MT. BMC Immunol. 2009 Feb 20;10:12. PMID: 19232107 doi:10.1186/1471-2172-10-12 In RAW 264.7 cells the induction of TNF-α production was highest in LPS and WB stimulated rather than the crimini, maitake, oyster, or shitake stimulated cells. The differences might be a result of differences in the quantity of the immunomodulatory substance or substances and or differences in solubility of mushrooms in the DMSO used to produce the extracts. However, the direction of the changes (increase versus decrease) were not different among the mushroom treatments. The lack of differential effects on cytokine secretion by the mushroom extracts suggests that the whole mushrooms must share a common component(s) that act to regulate immune function.
Matti Narkia

White button mushroom enhances maturation of bone marrow-derived dendritic cells and th... - 0 views

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    White button mushroom enhances maturation of bone marrow-derived dendritic cells and their antigen presenting function in mice.\nRen Z, Guo Z, Meydani SN, Wu D.\nJ Nutr. 2008 Mar;138(3):544-50.\nPMID: 18287364
Matti Narkia

Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs - 0 views

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    Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs.\nHeaney ML, Gardner JR, Karasavvas N, Golde DW, Scheinberg DA, Smith EA, O'Connor OA.\nCancer Res. 2008 Oct 1;68(19):8031-8.\nPMID: 18829561
Matti Narkia

Access : Tumours with PI3K activation are resistant to dietary restriction : Nature - 0 views

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    Tumours with PI3K activation are resistant to dietary restriction. Nada Y. Kalaany & David M. Sabatini Nature. Published online 11 March 2009 doi:10.1038/nature07782
Matti Narkia

Mechanisms underlying the biphasic effect of vitamin K1 (phylloquinone) on arterial blo... - 0 views

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    Mechanisms underlying the biphasic effect of vitamin K1 (phylloquinone) on arterial blood pressure.\nTirapelli CR, Resstel LB, de Oliveira AM, Corrêa FM.\nJ Pharm Pharmacol. 2008 Jul;60(7):889-93.\nPMID: 18549675 \nDOI: 10.1211/jpp.60.7.0010\n
Matti Narkia

[Action of soluble carbohydrates from avocado (Persea gratissima Gaertner) fruit on uti... - 0 views

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    [Action of soluble carbohydrates from avocado (Persea gratissima Gaertner) fruit on utilization of calcium in the rat] Raonimalala AF, Digaud A, Fournier P. Ann Nutr Aliment. 1980;34(4):735-44. French. PMID: 7224495
Matti Narkia

Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon ... - 0 views

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    Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer. Chapkin RS, Davidson LA, Ly L, Weeks BR, Lupton JR, McMurray DN. J Nutr. 2007 Jan;137(1 Suppl):200S-204S. PMID: 17182826
Matti Narkia

Dietary omega-3 polyunsaturated fatty acids promote colon carcinoma metastasis in rat l... - 0 views

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    Dietary omega-3 polyunsaturated fatty acids promote colon carcinoma metastasis in rat liver. Griffini P, Fehres O, Klieverik L, Vogels IM, Tigchelaar W, Smorenburg SM, Van Noorden CJ. Cancer Res. 1998 Aug 1;58(15):3312-9. PMID: 9699661
Matti Narkia

The beverage maté: a risk factor for cancer of the head and neck. - Head Neck... - 0 views

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    The beverage maté: a risk factor for cancer of the head and neck. Goldenberg D, Golz A, Joachims HZ. Head Neck. 2003 Jul;25(7):595-601. Review. PMID: 12808663 DOI: 10.1002/hed.10288
Matti Narkia

Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essentia... - 0 views

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    Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Xia S, Lu Y, Wang J, He C, Hong S, Serhan CN, Kang JX. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12499-504. Epub 2006 Aug 3. PMID: 16888035 doi: 10.1073/pnas.0605394103 In vitro experiments showed that addition of the n-3 fatty acid eicosapentaenoic acid or PGE(3) inhibited the growth of B16 cell line and increased the expression of PTEN, which could be partially attenuated by inhibition of PGE(3) production, suggesting that PGE(3) may act as an antitumor mediator. These data demonstrate an anticancer (antimelanoma) effect of n-3 fatty acids through, at least in part, activation of PTEN pathway mediated by PGE(3).
Matti Narkia

15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acut... - 0 views

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    15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation. Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N, Cooper D, Gilroy DW. J Exp Med. 2004 Jul 5;200(1):69-78. PMID: 15238606
Matti Narkia

Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the e... - 0 views

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    Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation. Schambach F, Schupp M, Lazar MA, Reiner SL. Eur J Immunol. 2007 Sep;37(9):2396-9. PMID: 17694576 DOI: 10.1002/eji.200737621
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic p... - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. n PMID: 19005974
Matti Narkia

Effects of Dietary Flaxseed on Intestinal Tumorigenesis in ApcMin Mouse - Nutrition and... - 0 views

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    Effects of dietary flaxseed on intestinal tumorigenesis in Apc(Min) mouse. Bommareddy A, Zhang X, Schrader D, Kaushik RS, Zeman D, Matthees DP, Dwivedi C. Nutr Cancer. 2009;61(2):276-83. PMID: 19235044 DOI: 10.1080/01635580802419764
Matti Narkia

Dietary Curcumin and Limonin Suppress CD4+ T-Cell Proliferation and Interleukin-2 Produ... - 0 views

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    These results suggest that combination chemotherapy (FO+Cur or Lim) may favorably modulate CD4+ T-cell-mediated inflammation.D ietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. Kim W, Fan YY, Smith R, Patil B, Jayaprakasha GK, McMurray DN, Chapkin RS. J Nutr. 2009 May;139(5):1042-8. Epub 2009 Mar 25. PMID: 19321585 doi:10.3945/jn.108.102772
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