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Matti Narkia

Hypovitaminosis D - Wikipedia, the free encyclopedia - 0 views

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    "Hypovitaminosis D is a deficiency of Vitamin D. It can result from: inadequate intake coupled with inadequate sunlight exposure (in particular sunlight with adequate ultra violet B rays), disorders that limit its absorption, conditions that impair conversion of vitamin D into active metabolites, such as liver or kidney disorders, or, rarely, by a number of hereditary disorders.[1] Deficiency results in impaired bone mineralization, and leads to bone softening diseases, rickets in children and osteomalacia in adults, and contributes to osteoporosis.[1] Osteomalacia may also occur rarely as a side-effect of phenytoin use

    Hypovitaminosis D is typically diagnosed by measuring the concentration in blood of the compound 25-hydroxyvitamin D (calcidiol), which is a precursor to the active form 1,25-dihydroxyvitamin D (calcitriol).[6] One recent review has proposed the following four categories for hypovitaminosis D:[7]

    * Insufficient 50-100 nmol/L (20-40 ng/mL)
    * Mild 25-50 nmol/L (10-20 ng/mL)
    * Moderate 12.5-25.0 nmol/L (5-10 ng/mL)
    * Severe < 12.5 nmol/L (< 5 ng/mL)

    Note that 1.0 nmol/L = 0.4 ng/mL for this compound.[8] Other authors have suggested that a 25-hydroxyvitamin D level of 75-80 nmol/L (30-32 ng/mL) may be sufficient
Matti Narkia

Urgent action needed to improve vitamin D status among older people in England! - [Age ... - 0 views

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    Urgent action needed to improve vitamin D status among older people in England!
    Hirani V, Tull K, Ali A, Mindell J.
    Age Ageing. 2009 Nov 23. [Epub ahead of print]
    PMID: 19934073

    CONCLUSIONS: poor vitamin D status of older people continues to be a public health problem in England. Hypovitaminosis D is associated with many risk factors and poor health outcomes. There is now an urgent need for a uniform policy on assessment and dietary supplementation of vitamin D in older people to prevent poor vitamin D status and its negative consequences
Matti Narkia

Hypovitaminosis D is associated with insulin resistance and {beta} cell dysfunction -- ... - 0 views

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    Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.
    Chiu KC, Chu A, Go VL, Saad MF.
    Am J Clin Nutr. 2004 May;79(5):820-5.
    PMID: 15113720

    Conclusions: The data show a positive correlation of 25(OH)D concentration with insulin sensitivity and a negative effect of hypovitaminosis D on ß cell function. Subjects with hypovitaminosis D are at higher risk of insulin resistance and the metabolic syndrome. Further studies are required to explore the underlying mechanisms.
Matti Narkia

Vitamin D Deficiency and Seasonal Variation in an Adult South Florida Population -- Lev... - 0 views

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    Vitamin d deficiency and seasonal variation in an adult South Florida population.
    Levis S, Gomez A, Jimenez C, Veras L, Ma F, Lai S, Hollis B, Roos BA.
    J Clin Endocrinol Metab. 2005 Mar;90(3):1557-62. Epub 2005 Jan 5.
    PMID: 15634725

    The prevalence of hypovitaminosis D is considerable even in southern latitudes and should be taken into account in the evaluation of postmenopausal and male osteoporosis.
Matti Narkia

A high prevalence of hypovitaminosis D in Finnish medical in- and outpatients. - J Inte... - 0 views

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    A high prevalence of hypovitaminosis D in Finnish medical in- and outpatients.
    Kauppinen-Mäkelin R, Tähtelä R, Löyttyniemi E, Kärkkäinen J, Välimäki MJ.
    J Intern Med. 2001 Jun;249(6):559-63.
    PMID: 11422663
    DOI: 10.1046/j.1365-2796.2001.00847.x

    CONCLUSION: Hypovitaminosis D is very common amongst Finnish in- and outpatients in both sexes, causing secondary hyperparathyroidism in females. More extensive studies are warranted to elucidate the vitamin D status of the Finnish population.
Matti Narkia

Half of the patients with an acute hip fracture suffer from hypovitaminosis D: a prospe... - 0 views

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    Half of the patients with an acute hip fracture suffer from hypovitaminosis D: a prospective study in southeastern Finland.
    Nurmi I, Kaukonen JP, Lüthje P, Naboulsi H, Tanninen S, Kataja M, Kallio ML, Leppilampi M.
    Osteoporos Int. 2005 Dec;16(12):2018-24. Epub 2005 Aug 24.
    PMID: 16133642

    Half of the patients with a hip fracture suffered from hypovitaminosis D. The situation was worst in institutional and residential care, although there are personnel for taking care of vitamin D supplementation. In the late summer, one-third and in late winter two-thirds of the patients suffered from hypovitaminosis D. The geographical location of Finland indicates extensive efforts to increase the use of vitamin D supplements among elderly.
Matti Narkia

Vitamin D requirements during lactation: high-dose maternal supplementation as therapy ... - 0 views

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    Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infant.
    Hollis BW, Wagner CL.
    Am J Clin Nutr. 2004 Dec;80(6 Suppl):1752S-8S.
    PMID: 15585800
Matti Narkia

The prevalence of hypovitaminosis D among US adults: data from the NHANES III. - [Ethn ... - 0 views

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    The prevalence of hypovitaminosis D among US adults: data from the NHANES III.
    Zadshir A, Tareen N, Pan D, Norris K, Martins D.
    Ethn Dis. 2005 Autumn;15(4 Suppl 5):S5-97-101.
    PMID: 16315387

    CONCLUSION: Serum levels of 25(OH) D3 are below the recommended levels for a large portion of the general adult population and in most minorities. Need exists for a critical review and probable revision of current recommendations for adult vitamin D intake to maintain adequate 25(OH) D3 levels.
Matti Narkia

NEJM -- Hypovitaminosis D in Medical Inpatients - 0 views

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    Hypovitaminosis D in medical inpatients.
    Thomas MK, Lloyd-Jones DM, Thadhani RI, Shaw AC, Deraska DJ, Kitch BT, Vamvakas EC, Dick IM, Prince RL, Finkelstein JS.
    N Engl J Med. 1998 Mar 19;338(12):777-83.
    PMID: 9504937

    Conclusions Hypovitaminosis D is common in general medical inpatients, including those with vitamin D intakes exceeding the recommended daily amount and those without apparent risk factors for vitamin D deficiency.
Matti Narkia

Vitamin D intake is low and hypovitaminosis D comm...[Eur J Clin Nutr. 1999] - PubMed R... - 0 views

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    Vitamin D intake is low and hypovitaminosis D common in healthy 9- to 15-year-old Finnish girls.
    Lehtonen-Veromaa M, Möttönen T, Irjala K, Kärkkäinen M, Lamberg-Allardt C, Hakola P, Viikari J.
    Eur J Clin Nutr. 1999 Sep;53(9):746-51.
    PMID: 10509773

    CONCLUSION: Hypovitaminosis D is fairly common in growing Finnish girls in the wintertime, and three months of vitamin D supplementation with 10 microg/d was insufficient in preventing hypovitaminosis D. The daily dietary vitamin D intake was insufficient (< 5 microg/d) in the majority of participants, while the calcium intake was usually sufficient.
Matti Narkia

Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of d... - 0 views

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    Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors.
    Hyppönen E, Power C.
    Am J Clin Nutr. 2007 Mar;85(3):860-8.
    PMID: 17344510

    Conclusion: Prevalence of hypovitaminosis D in the general population was alarmingly high during the winter and spring, which warrants action at a population level rather than at a risk group level.

    Data from the 1958 birth cohort suggest that, at different cutoffs for hypovitaminosis D, a substantial public health problem exists in British whites. Obese participants and those living in Scotland were at the highest risk of hypovitaminosis D. However, the prevalence in the general population was very high during the winter and spring, which suggests that, to improve the situation, action is required at a population level rather than at a risk-group level. In the United States, calls have gone out for an increase in vitamin D fortification of foods (11), and the data from the current study suggest that such action is also warranted in the United Kingdom. Vitamin D is currently available without prescription as a dietary supplement only as part of cod liver oil or multivitamin products; hence, a need clearly exists to consider increased availability of over-the-counter supplements. Hypovitaminosis D has been implicated in the development of serious conditions, including diabetes, various types of cancer, and cardiovascular diseases, in addition to its essential role in maintaining bone health (1, 2). The high rates of hypovitaminosis D reported in this study suggest that immediate action is needed to improve the vitamin D status of the British population.
Matti Narkia

Global vitamin D status and determinants of hypovitaminosis D - SpringerLink - Journal... - 0 views

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    Global vitamin D status and determinants of hypovitaminosis D.
    Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, El-Hajj Fuleihan G, Josse RG, Lips P, Morales-Torres J; on behalf of the IOF Committee of Scientific Advisors (CSA) Nutrition Working Group.
    Osteoporos Int. 2009 Jun 19. [Epub ahead of print]
    PMID: 19543765

    CONCLUSION: Reports from across the world indicate that hypovitaminosis D is widespread and is re-emerging as a major health problem globally.
Matti Narkia

Guarding Against the Dangers of Vitamin D Deficiency - LE Magazine May 2007 - 0 views

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    Guarding Against the Dangers of Vitamin D Deficiency
    By Tiesha D. Johnson, BSN, RN
    LE Magazine May 2007
    Print Friendly
Matti Narkia

Le Magazine May 2007 - Report: Guarding Against The Dangers Of Vitamin D Deficiency - 0 views

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    Guarding Against the Dangers of Vitamin D Deficiency
    By Tiesha D. Johnson, BSN, RN
    LE Magazine May 2007
Matti Narkia

The High Prevalence of Vitamin D Insufficiency cross Australian Populations Is Only Par... - 0 views

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    van der Mei IA, Ponsonby AL, Engelsen O, Pasco JA, McGrath JJ, Eyles DW, Blizzard L, Dwyer T, Lucas R, Jones G.
    The High Prevalence of Vitamin D Insufficiency across Australian Populations Is Only Partly Explained by Season and Latitude.
    Environ Health
Matti Narkia

Prevalence of vitamin D inadequacy in European postmenopausal women - Curr Med Res Opin... - 0 views

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    Reginster JY.
    Prevalence of vitamin D inadequacy in European postmenopausal women.
    Curr Med Res Opin. 2007 Jul 12; [Epub ahead of print]
    PMID: 17631697 [PubMed - as supplied by publisher]
Matti Narkia

Correlation between vitamin D3 deficiency and insulin resistance in pregnancy - Wiley I... - 0 views

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    Maghbooli Z, Hossein-Nezhad A, Karimi F, Shafaei AR, Larijani B.
    Correlation between vitamin D(3) deficiency and insulin resistance in pregnancy.
    Diabetes Metab Res Rev. 2007 Jul 2; [Epub ahead of print]
    PMID: 17607661 [PubMed - as supplied by publish
Matti Narkia

Hypocalcemia as a Cause of Reversible Cardiomyopathy with Ventricular Tachycardia -- Ch... - 0 views

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    Hypocalcemia as a Cause of Reversible Cardiomyopathy with Ventricular Tachycardia
    Chandrakant B. Chavan, MD, DNB; Kalavakolanu Sharada, MD, DM; Hygriv B. Rao, MD, DM; and Calambur Narsimhan, MD, DM, AB
    Annals of Internal Medicine, 3 April 2007, Volume
Matti Narkia

Low vitamin D status: a contributing factor in the pathogenesis of congestive heart fai... - 0 views

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    Zittermann A, Schleithoff SS, Tenderich G, Berthold HK, Korfer R, Stehle P.
    Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure?
    J Am Coll Cardiol. 2003 Jan 1;41(1):105-12.
    PMID: 12570952 [PubMed - indexed for M
Matti Narkia

Putting cardiovascular disease and vitamin D insufficiency into perspective. - 0 views

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    Zittermann A, Schleithoff SS, Koerfer R. Putting cardiovascular disease and vitamin D insufficiency into perspective.Br J Nutr. 2005 Oct;94(4):483-92. Review.PMID: 16197570 [PubMed - indexed for MEDLINE]
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