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Dietary-supplement firms fight McCain « World Vitamins Online - 0 views

    The dietary-supplement industry is fighting a bid by U.S. Sen. John McCain to force it to disclose ingredients and register with the Food and Drug Administration.
Matti Narkia

Meta-analysis of prospective cohort studies evaluating the association of saturated fat... - 2 views

    Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.
    Siri-Tarino PW, Sun Q, Hu FB, Krauss RM.
    Am J Clin Nutr. 2010 Jan 13. [Epub ahead of print]
    PMID: 20071648

    Conclusions: A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat.
Matti Narkia

Healthwise Knowledgebase : University of Michigan Health System - 0 views

    "Healthwise Knowledgebase
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    All [0-9] A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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    To search for a specific topic enter a keyword in the search box and review the results below. "
Matti Narkia

The hypoglycemic effect of fat and protein is not attenuated by insulin resistance -- L... - 0 views

    The hypoglycemic effect of fat and protein is not attenuated by insulin resistance.
    Lan-Pidhainy X, Wolever TM.
    Am J Clin Nutr. 2009 Nov 18. [Epub ahead of print]
    PMID: 19923374

    Conclusions: The hypoglycemic effect of fat and protein was not blunted by insulin resistance. Protein increased insulin but had no effect on C-peptide or the insulin secretion rate, which suggests decreased hepatic insulin extraction or increased C-peptide clearance.
Matti Narkia

Cardiovascular disease risk of dietary stearic acid compared with trans, other saturate... - 0 views

    Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review1,3.
    Hunter JE, Zhang J, Kris-Etherton PM.
    Am J Clin Nutr. 2009 Nov 25. [Epub ahead of print]
    PMID: 19939984

    Conclusions: TFA intake should be reduced as much as possible because of its adverse effects on lipids and lipoproteins. The replacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats beneficially affects LDL cholesterol, the primary target for CVD risk reduction; unsaturated fats are preferred for liquid fat applications. Research is needed to evaluate the effects of STA on emerging CVD risk markers such as fibrinogen and to understand the responses in different populations.
Matti Narkia

Vitamins can be useful, says FDA - 1 views

    "The US Food and Drug Administration has advised consumers that certain vitamin supplements "can be useful", stating that "there are many good reasons" to consider taking them.

    The consumer advisory, released this week in video and text format, comes at a time of increased pressure on the supplements industry, with media outlets repeatedly questioning the usefulness and safety of dietary supplements.

    "Supplements can be useful when they fulfill a specific identified nutrient need that can't be met by food or is not being met through normal food intake," said Barbara Schneeman, PhD, director of FDA's Office of Nutritional Products, Labeling, and Dietary Supplements.

    The message is one that dietary supplement trade groups have consistently tried to get across, with campaigns such as CRN's Life…supplemented set up to communicate the importan

    Vitamins for the right reasons

    According to FDA's consumer update - Fortify Your Knowledge About Vitamins - there are many good reasons to consider taking vitamin supplements, which could be recommended by a doctor in a number of situations, including:

    * For certain health problems
    * When following a vegetarian or vegan diet
    * When pregnant or breastfeeding

    Iron and folic acid are important for pregnant women or women of childbearing age, to be consumed via a varied diet or from fortified foods and supplements, says FDA. People over 50 should consume vitamin B12, and those with darker skin or with insufficient exposure to sunlight should consume extra vitamin D, again via fortified foods or supplements."
Matti Narkia

n-3 Fatty acids and cardiovascular disease -- Breslow 83 (6): S1477 -- American Journal... - 0 views

    n-3 fatty acids and cardiovascular disease.
    Breslow JL.
    Am J Clin Nutr. 2006 Jun;83(6 Suppl):1477S-1482S. Review.
    PMID: 16841857

    The results of prospective cohort studies indicate that consuming fish or fish oil containing the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is associated with decreased cardiovascular death, whereas consumption of the vegetable oil-derived n-3 fatty acid {alpha}-linolenic acid is not as effective. Randomized control trials (RCTs) in the context of secondary prevention also indicate that the consumption of EPA plus DHA is protective at doses <1 g />3 g/d, EPA plus DHA can improve cardiovascular disease risk factors, including decreasing plasma triacylglycerols, blood pressure, platelet aggregation, and inflammation, while improving vascular reactivity. Mainly on the basis of the results of RCTs, the American Heart Association recommends that everyone eat oily fish twice per week and that those with coronary heart disease eat 1 g/d of EPA plus DHA from oily fish or supplements. Directions for future research include 1) RCTs to confirm the initial trials showing that EPA plus DHA decreases cardiovascular death and additional studies to determine whether this effect is due to EPA, DHA, or the combination; the dosage of the effective components; and whether the mechanism of action in humans is prevention of fatal arrhythmias. 2) Clinical studies to determine whether the reduction in cardiovascular disease risk factors is due to EPA, DHA, or the combination and the dosage of the effective components. 3) Clinical studies to determine whether vegetable oil-derived {alpha}-linolenic acid added to a diet enriched in n-6 fatty acids can effectively substitute for fish oil-derived EPA plus DHA.
Matti Narkia

High dietary methionine intake increases the risk of acute coronary events in middle-ag... - 0 views

    High dietary methionine intake increases the risk of acute coronary events in middle-aged men.
    Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT.
    Nutr Metab Cardiovasc Dis. 2006 Mar;16(2):113-20. Epub 2005 Nov 2.
    PMID: 16487911

    The main finding of this study is that long-term, moderately high dietary methionine intake may increase the risk of acute coronary events in middle-aged Finnish men free of prior CHD. More prospective research is needed to confirm the role of dietary methionine in the development of CVD, and whether its effects are independent of homocysteine.
Matti Narkia

Fat in diet won't affect weight gain over time | Reuters - 1 views

    "NEW YORK (Reuters Health) - People who want to maintain a healthy weight over time shouldn't obsess about their fat intake, new research shows.

    The percentage of calories that a person got from fat, as opposed to protein or carbohydrates, had nothing to do with how much weight they gained in the coming years, the research team found.

    The kinds of fat they ate didn't matter either, Dr. Nita Forouhi of the Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK and her colleagues found.

    The findings, Forouhi noted in an email to Reuters Health, show that "it is more important to aim for a healthy lifestyle including a balanced healthy diet and regular physical activity, than to focus on fat intake alone as a factor for weight gain.""
Matti Narkia

Seasonality of UV-radiation and vitamin D status at 69 degrees north. - Photochem Photo... - 1 views

    Seasonality of UV-radiation and vitamin D status at 69 degrees north.
    Brustad M, Edvardsen K, Wilsgaard T, Engelsen O, Aksnes L, Lund E.
    Photochem Photobiol Sci. 2007 Aug;6(8):903-8. Epub 2007 Jun 27.
    PMID: 17668121

    The generally high dietary intakes of vitamin D, especially in winter, mask largely the effect of seasonal variation in UV-exposure, causing an atypical seasonal variation in vitamin D status. The UV-hour variable significantly predicted 25(OH)D levels in blood when adjusted for intakes and artificial UV-radiation exposure and sun holidays abroad.
Matti Narkia

Age and Dietary Form of Vitamin K Affect Menaquinone-4 Concentrations in Male Fischer 3... - 0 views

    Age and dietary form of vitamin K affect menaquinone-4 concentrations in male Fischer 344 rats.
    Booth SL, Peterson JW, Smith D, Shea MK, Chamberland J, Crivello N.
    J Nutr. 2008 Mar;138(3):492-6.
    PMID: 18287355

    These data suggest that dihydrophylloquinone, which differs from phylloquinone in its side phytyl chain, is absorbed but its intake results in less MK-4 in certain tissues. Dihydrophylloquinone may be used in models for the study of tissue-specific vitamin K deficiency
Matti Narkia

Conversion of Dietary Phylloquinone to Tissue Menaquinone-4 in Rats is Not Dependent on... - 0 views

    Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria.
    Davidson RT, Foley AL, Engelke JA, Suttie JW.
    J Nutr. 1998 Feb;128(2):220-3.
    PMID: 9446847

    These data offer conclusive proof that the tissue-specific formation of MK-4 from K is a metabolic transformation that does not require bacterial transformation to menadione as an intermediate in the process
Matti Narkia

Whole Health Source: Butyric Acid: an Ancient Controller of Metabolism, Inflammation an... - 0 views

    "Susceptible strains of rodents fed high-fat diets overeat, gain fat and become profoundly insulin resistant. Dr. Jianping Ye's group recently published a paper showing that the harmful metabolic effects of a high-fat diet (lard and soybean oil) on mice can be prevented, and even reversed, using a short-chain saturated fatty acid called butyric acid (hereafter, butyrate).

    The butyrate-fed mice remained lean and avoided metabolic problems. Butyrate increased their energy expenditure by increasing body heat production and modestly increasing physical activity. It also massively increased the function of their mitochondria, the tiny power plants of the cell."
Matti Narkia

Nordic Nutrition Recommendations 2004 - Norden - 0 views

    "The Nordic countries have for several decades collaborated in setting guidelines for dietary composition and recommended intakes of nutrients. This 4th edition, NNR 2004, contains a summary, presented in Chapters 1 and 2, while the subsequent chapters provide the scientific background documentation. Recommendations have been changed only when strong scientific evidence has evolved since the 3rd edition. A Nordic perspective has been accounted for in setting the recommendations."
Matti Narkia

Types of Dietary Fat and Risk of Coronary Heart Disease: A Critical Review -- Hu et al.... - 0 views

    Types of dietary fat and risk of coronary heart disease: a critical review.
    Hu FB, Manson JE, Willett WC.
    J Am Coll Nutr. 2001 Feb;20(1):5-19. Review.
    PMID: 11293467
Matti Narkia

A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors an... - 0 views

    A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
    Mente A, de Koning L, Shannon HS, Anand SS.
    Arch Intern Med. 2009 Apr 13;169(7):659-69. Review.
    PMID: 19364995

    Conclusions The evidence supports a valid association of a limited number of dietary factors and dietary patterns with CHD. Future evaluation of dietary patterns, including their nutrient and food components, in cohort studies and randomized trials is recommended
Matti Narkia

Egg consumption and endothelial function: a randomized controlled crossover trial - 0 views

    Egg consumption and endothelial function: a randomized controlled crossover trial.
    Katz DL, Evans MA, Nawaz H, Njike VY, Chan W, Comerford BP, Hoxley ML.
    Int J Cardiol. 2005 Mar 10;99(1):65-70.
    PMID: 15721501

    Conclusion: Short-term egg consumption does not adversely affect endothelial function in healthy adults, supporting the view that dietary cholesterol may be less detrimental to cardiovascular health than previously thought
Matti Narkia

Single food focus dietary guidance: lessons learned from an economic analysis of egg co... - 0 views

    Single food focus dietary guidance: lessons learned from an economic analysis of egg consumption.
    Schmier JK, Barraj LM, Tran NL.
    Cost Eff Resour Alloc. 2009 Apr 14;7:7.
    PMID: 19366457

    A risk apportionment model estimated the increased risk for coronary heart disease (CHD) attributable to egg cholesterol content, the decreased risk for other conditions (age-related macular degeneration (AMD), cataract, neural tube defects, and sarcopenia) associated with egg consumption, and a literature search identified the cost of illness of each condition. The base 795 case scenario calculated the costs or savings of each condition attributable to egg cholesterol or nutrient content.

    Given the costs associated with CHD and the benefits associated with the other conditions, the most likely scenario associated with eating an egg a day is savings of $2.82 billion annually with uncertainty ranging from a net cost of $756 million to net savings up to $8.50 billion.

    This study evaluating the economic impact of egg consumption suggests that public health campaigns promoting limiting egg consumption as a means to reduce CHD risk would not be cost-effective from a societal perspective when other benefits are considered. Public health intervention that focuses on a single dietary constituent, and foods that are high in that constituent, may lead to unintended consequences of removing other beneficial constituents and the net effect may not be in its totality a desirable public health outcome. As newer data become available, the model should be updated.
Matti Narkia

Dietary cholesterol and the risk of cardiovascular disease in patients: a review of the... - 0 views

    Dietary cholesterol and the risk of cardiovascular disease in patients: a review of the Harvard Egg Study and other data.
    Jones PJ.
    Int J Clin Pract Suppl. 2009 Oct;(163):1-8, 28-36. English, French.
    PMID: 19751443

    For many years, both the medical community and the general public have incorrectly associated eggs with high serum cholesterol and being deleterious to health, even though cholesterol is an essential component of cells and organisms. It is now acknowledged that the original studies purporting to show a linear relation between cholesterol intake and coronary heart disease (CHD) may have contained fundamental study design flaws, including conflated cholesterol and saturated fat consumption rates and inaccurately assessed actual dietary intake of fats by study subjects. Newer and more accurate trials, such as that conducted by Frank B. Hu of the Harvard School of Public Health (1999), have shown that consumption of up to seven eggs per week is harmonious with a healthful diet, except in male patients with diabetes for whom an association in higher egg intake and CHD was shown. The degree to which serum cholesterol is increased by dietary cholesterol depends upon whether the individual's cholesterol synthesis is stimulated or down-regulated by such increased intake, and the extent to which each of these phenomena occurs varies from person to person. Several recent studies have shed additional light on the specific interplay between dietary cholesterol and cardiovascular health risk. It is evident that the dynamics of cholesterol homeostasis, and of development of CHD, are extremely complex and multifactorial. In summary, the earlier purported adverse relationship between dietary cholesterol and heart disease risk was likely largely over-exaggerated.
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