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Vitamin D3 shown to reduce CRP, TNF, IL-6, IL-1B, IL-8 in colorectal adenoma patients. This study supports the anti-inflammatory, anti-cancer benefits of vitamin D3.

Oral vitamin C shown to reduce fast blood glucose, post meal blood glucose, and HgbA1C.  This study was down with metformin.  Vitamin C was used with metformin in those with type II DM.  This supports the use of vitamin C in blood sugar control.  Vitamin C does not increase blood glucose levels.

Calorie restriction increases adiponectin secretion from adipocytes.  Another plus of calorie restriction.  Remember, adiponectin and insulin are inversely associated.  Granted, this is in a rat model, but still supporting the overall health benefits of calorie restriction.

antioxidant support in early pregnancy, including NAC, shown to reduce the incidence in pre-eclampsia

nice review of low Testosterone, the metabolic dysfunction as a result of low T, Testosterone therapy, and things to consider when supporting Testosterone.

2008 article from diabetes.  This article supports metabolic endotoxemia arising out of the gut.  High fat diet intake results in disrupted gut flora, resulting in increrased LPS release, resulting in inflammation, leads to leaky gut, systemic endotoxemia, inflammation, and thus metabolic dysfunction: see obesity, DM..

TPN was found to be safe for nutritional support during the first trimester in those women suffering from hyperemesis gravidarum

LDL shown to not be a major contributor to death.  Despite what the commercials on TV show, the studies don't support the vilification of LDL.

Is all cholesterol bad?  Of course not.  We have got to get away from the linear thinking that plagues medicine.  This article proposes and supports  a protective claim of lipoproteins: VLDL, LDL, Lp(a), and HDL.  Even shown to protect against bacterial, viral, LPS, and parasitic infectious damage.

nice review of natural therapies for scleroderma.  Life extensions always does a great job of supporting natural therapies with science.

Review of the science that support natural therapies in scleroderma.

New cohort study finds increased risk of Testosterone in men > 65 and those : these are based in marketing-based medicine not evidence based medicine.

Another support point for Estrogen as a cause of low Testosterone.  This animal study points to signaling of Estradiol through ER alpha.  This study found high expression of ER alpha and subsequent signaling by E2 decreased cAMP and Nur77 transcription factor.  Nur77 increases steroid synthesis.  This was confirmed with ER alpha knockout mice.

Study finds negligible effect of Testosterone therapy (4.8 mg) on PSA.  The study consisted of several phases, the longest being 6 years.  However, each phase the parcipitants significantly declined.  The long held belief that Testosterone and DHT promote an increase in PSA is just not supported in the science.  In fact, aromatase knockout mice don't develop prostate cancer, only BPH.

randomized study finds no difference in attention, memory in children born to mothers supplementing with DHA.  Good randomized design, but several problems.  First, did these women need supplementation.  No testing was done to determine need.  They may have needed more or none at all--the standard throw a dart on the wall and hope it sticks paradigm.  Second, Neurologcial development starts from day one, so do properly determine effect, the authors need to start support at conception or even better- before.  This follows that logic that women desiring conception should start extra folic acid 3 months prior. The literature is moving in the right direction, but they are still limiting themselves.  

I think the authors missed the points to be taken from their research:prostate cancer patients had "lower concentrations of total Testosterone, free Testosterone, and bioavailable Testosterone" versus controls that were prostate cancer free.  This provides additional support that prostate cancer is not a androgen driven disease.

IV vitamin C at 50 grams twice weekly shown to reduce side effects associated with chemotherapy.  Granted, this is a single case study without comparison, but this is supported by other studies.

Great article chronicles the biochemistry of "over nutrition" and inflammation through NF-kappaB activation and its impact on the brain.

Studies like this surprise me. This study lauds the benefit of metformin as a breast cancer protective in postmenopuasal womb.  Their focus is on the bandaid--the prescription drug.  They completely ignore the cause--glucose.  The Warburg effect in cancer is well known.  Limit simple sugar intake and support oxidative phosphorylation will do the same.  That is treating the cause.

Study supports the mechanism behind endocrine disruption of xenoestrogens in the pubertal development of young boys.