N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic ... - 0 views
There is a marked increase in expression of TNF in active multiple sclerosis (MS)
a correlation exists between cerebrospinal fluid levels of TNF and the severity and progression of disease
With cytokine activation, free-radical production increases and this has been demonstrated in MS
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NAC inhibits the toxicity of TNF and in an animal model of MS