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Nathan Goodyear

N-Acetylcysteine for Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis o... - 0 views

  • compared effects of NAC with placebo or metformin in women with PCOS
  • NAC significantly improved rates of live births and spontaneous ovulation compared to placebo in women with PCOS
  • we found no evidence of effects of NAC on improving menstrual regularity, acne, hirsutism, BMI, fasting insulin, fasting glucose, or HOMA-IR
  • ...3 more annotations...
  • NAC was not associated with greater benefits to metformin for improving pregnancy rate, spontaneous ovulations, and menstrual regularity
  • Metformin also improved the BMI, total testosterone, insulin level, and lipid levels compared to NAC
  • All the studies were of short duration (three months)
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    Data review finds NAC improves pregnancy rates and ovulation rates in women with PCOS against placebo.  Meta-analysis revealed limited studies on the topic.  When compared to metformin, there was no difference found.  Though, one wonders if attacking insulin resistance through proper diet and additional neutraceutical approach would negate that.  The reason?  NAC and metformin are working in different biochemical pathways.  The authors here seem to not realize this. It appears that they think NAC and metormin are both working in the same manner, but they don't.  The fact that there is still benefit found compared to placebo, despited the authors lack of understanding of what NAC is and does is a positive.
Nathan Goodyear

Glutathione supplementation improves macrophage functions in HIV. - PubMed - NCBI - 0 views

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    reduced glutathione, via increased oxidative stress, levels lost in HIV.  NAC and liposomal Glutathione increased innate immune function--macrophages.
Nathan Goodyear

A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism - 0 views

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    900 mg of NAC over short 4 week course provided significant improvement in behavior of children with autism.  No pre treatment evaluation was performed.  One wonders if therapeutic therapy was actually undertaken if the results would have been better.  NAC is a precursor to Glutathione production and detoxification compromise is common place in autism.
Nathan Goodyear

High-Dose NAC Improves Small Airway Function in COPD - Natural Medicine Journal: The Of... - 0 views

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    NAC reduced COPD exacerbation and hospitalization versus placebo.  The dosing and the duration of this study was low and short respectively. 
Nathan Goodyear

Scopus preview - Scopus - Document details - 0 views

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    Mercury decreases levels of superoxide dismutase in the lungs of rats exposed.  This study found NAC found to be protective.
Nathan Goodyear

Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity ... - 0 views

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    N-acetylcysteine, also known as NAC, a precursor to glutathione, is shown to significantly reduce the incidence of flu symptoms.  NAC should be taken through out the winter months as a flu prevention?  Well, this study does not support that, but if one gets the flu, NAC will significantly reduce the flu symptoms.
Nathan Goodyear

Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease - 0 views

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    NAC shown to improve secondary measures of cognitive function in small study in those with Alzheimer's disease. NAC proves to be a reliable means to reduce free radical induced advanced glycation end productions and resultant inflammation. Also was shown to be well tolerated.
Nathan Goodyear

Lower Rate of Preeclampsia After Antioxidant Supplementation in Pregnant Women with Low... - 0 views

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    antioxidant support in early pregnancy, including NAC, shown to reduce the incidence in pre-eclampsia
Nathan Goodyear

N-Acetylcysteine: Multiple Clinical Applications - August 1, 2009 - American Family Phy... - 0 views

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    use of NAC provides many health benefits above and beyond tylenol overdose.
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