Group items tagged colorectal - Dr. Goodyear

Sex Hormones and Colorectal Cancer: What Have We Learned So Far? - 0 views

jnci.oxfordjournals.org/...jnci.djq444.full

hormones colon colorectal cancer

shared by Nathan Goodyear on 09 Jun 14 - No Cached

Nathan Goodyear on 09 Jun 14

This article focus' more on the risks of colorectal cancer in men. It does perform a mini-review on risks for women. It appears progesterone is important in prevention of colorectal cancer in women. Post-menopause, women with HRT have a reduced risk. In contrast, men with androgen deprivation therapy, there is an increase risk of colorectal cancer.

<div class="cArrow"> </div><div class="cContentInner">This article focus' more on the risks of colorectal cancer in men. It does perform a mini-review on risks for women. It appears progesterone is important in prevention of colorectal cancer in women. Post-menopause, women with HRT have a reduced risk. In contrast, men with androgen deprivation therapy, there is an increase risk of colorectal cancer.</div>

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http://www.turkjcancer.org/pdf/pdf_TJC_489.pdf - 0 views

www.turkjcancer.org/...pdf_TJC_489.pdf

colon colorectal cancer ER PR estrogen receptor estrogen receptors progesterone receptor progesterone receptors

shared by Nathan Goodyear on 09 Jun 14 - No Cached

Nathan Goodyear on 09 Jun 14

The relationship between ER and PR and colorectal cancer is yet to be determined. It is not outside the realm of possibility that a standardization of ER/PR in colorectal cancer is unlikely. Each cancer is unique. There are probably some generalizations that can be made, but complete generalizations of ER/PR in colorectal cancer in women is unlikely.

<div class="cArrow"> </div><div class="cContentInner">The relationship between ER and PR and colorectal cancer is yet to be determined. It is not outside the realm of possibility that a standardization of ER/PR in colorectal cancer is unlikely. Each cancer is unique. There are probably some generalizations that can be made, but complete generalizations of ER/PR in colorectal cancer in women is unlikely.</div>

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JAMA Network | JAMA: The Journal of the American Medical Association | Low-Fat Dietary ... - 0 views

jama.jamanetwork.com/article.aspx

low fat diet colorectal cancer cancer women dietary

shared by Nathan Goodyear on 13 Jun 12 - No Cached

Nathan Goodyear on 13 Jun 12

The women's health initiative dietary modification trial of almost 50,000 women found no association between a low fat diet and a reduction of colorectal cancer. Translation: a low fat diet does not lower the risk of colorectal cancer.

<div class="cArrow"> </div><div class="cContentInner">The women's health initiative dietary modification trial of almost 50,000 women found no association between a low fat diet and a reduction of colorectal cancer. Translation: a low fat diet does not lower the risk of colorectal cancer.</div>

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Reproductive History and risk of colorectal cancer in postmenopausal women - 0 views

jnci.oxfordjournals.org/...jnci.djr101.full.pdf

colon cancer colorectal estrogen post-menopause

shared by Nathan Goodyear on 19 Nov 13 - No Cached

Nathan Goodyear on 19 Nov 13

study finds prolonged exposure to estrogen associated with increased colorectal cancer risk in postmenopausal women. So many unanswered questions. What was the ER status of these patients? What was the weight of these patients? One cannot simply compare estrogen exposure to colorectal cancer risk and say aha! What is the environment of the individual(s)?!

<div class="cArrow"> </div><div class="cContentInner">study finds prolonged exposure to estrogen associated with increased colorectal cancer risk in postmenopausal women. So many unanswered questions. What was the ER status of these patients? What was the weight of these patients? One cannot simply compare estrogen exposure to colorectal cancer risk and say aha! What is the environment of the individual(s)?!</div>

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A Case of Colorectal Cancer during Pregnancy: A Brief Review of the Literature - 0 views

www.hindawi.com/...626393

colon cancer colorectal pregnancy hormone hormones

shared by Nathan Goodyear on 09 Jun 14 - No Cached

Nathan Goodyear on 09 Jun 14

This case study reveals the complexity of cancer. HRT and pregnancy have generally been shown to be protective against the incidence of colorectal cancer in women. Yet, here colorectal cancer was diagnosed in the postpartum period. Whether the high estrogen and progesterone during pregnancy played a role here is difficult to determine.

<div class="cArrow"> </div><div class="cContentInner">This case study reveals the complexity of cancer. HRT and pregnancy have generally been shown to be protective against the incidence of colorectal cancer in women. Yet, here colorectal cancer was diagnosed in the postpartum period. Whether the high estrogen and progesterone during pregnancy played a role here is difficult to determine.</div>

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American Journal of Gastroenterology - Abstract of article: Diagnostic Precision of Fec... - 0 views

www.nature.com/...ajg2007150a.html

IBD IBS inflammation gut GI Calprotectin colorectal cancer cancer inflammatory bowel disease

shared by Nathan Goodyear on 21 May 14 - No Cached

Nathan Goodyear on 21 May 14

Fecal calprotectin is found to be a much better screening test for IBD than colorectal cancer. Though, fecal Calprotectin levels were found to be elevated in colorectal cancer compared to controls, the sensitivity and specificity was low. In contrast, a fecal Calprotectin > 100 mg/g, in this study, was found to be specific and sensitive for IBD and excluding IBS.

<div class="cArrow"> </div><div class="cContentInner">Fecal calprotectin is found to be a much better screening test for IBD than colorectal cancer. Though, fecal Calprotectin levels were found to be elevated in colorectal cancer compared to controls, the sensitivity and specificity was low. In contrast, a fecal Calprotectin > 100 mg/g, in this study, was found to be specific and sensitive for IBD and excluding IBS.</div>

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http://www.scielo.oces.mctes.pt/pdf/ge/v13n3/v13n3a06 - 0 views

www.scielo.oces.mctes.pt/...v13n3a06

streptococcus gallolyticus colon polyps rectal colorectal

shared by Nathan Goodyear on 28 Apr 14 - No Cached

Nathan Goodyear on 28 Apr 14

People with Streptococcus gallolyticus found to be associated with higher incidence of colon polyps. This in light of the known association between Steptococcus gallolyticus and colorectal cancer puts a target on Steptococcus gallolyticus in those at risk for colorectal cancer.

<div class="cArrow"> </div><div class="cContentInner">People with Streptococcus gallolyticus found to be associated with higher incidence of colon polyps. This in light of the known association between Steptococcus gallolyticus and colorectal cancer puts a target on Steptococcus gallolyticus in those at risk for colorectal cancer.</div>

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Exercise improves survival rates for colorectal cancer patients - Dana-Farber Cancer In... - 0 views

www.dana-farber.org/...olorectal-cancer-patients.aspx

cancer colorectal exercise survival rates

shared by Nathan Goodyear on 28 Apr 14 - No Cached

Nathan Goodyear on 28 Apr 14

Men with colorectal cancer that engage in "moderate" exercise live longer than those that don't. Moderate was described as 1 hour of walking 6 days weekly.

<div class="cArrow"> </div><div class="cContentInner">Men with colorectal cancer that engage in "moderate" exercise live longer than those that don't. Moderate was described as 1 hour of walking 6 days weekly.</div>

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Immunohistochemical Expression of Estrogen and Progesterone Receptors in Human Colorect... - 0 views

www.ncbi.nlm.nih.gov/...PMC3215447

estrogen progesterone ER estrogen receptor estrogen receptors ER alpha ER beta ER-alpha ER-beta PR progesterone receptor progesterone receptors

shared by Nathan Goodyear on 09 Jun 14 - No Cached

Nathan Goodyear on 09 Jun 14

Study finds ER and PR increase along the timeline of tumor initiation. The authors point to likely association that ER and PR expression is associated with and key to initiating colorectal transformation. A lot to be determined from this study. IF this were entirely true, then what to explain the 35% lower colorectal cancer risk in women vs men? Likely ER and PR pertubance plays a significant role is likely, but the mere expression--yet to be determined.

<div class="cArrow"> </div><div class="cContentInner">Study finds ER and PR increase along the timeline of tumor initiation. The authors point to likely association that ER and PR expression is associated with and key to initiating colorectal transformation. A lot to be determined from this study. IF this were entirely true, then what to explain the 35% lower colorectal cancer risk in women vs men? Likely ER and PR pertubance plays a significant role is likely, but the mere expression--yet to be determined.</div>

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Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorect... - 0 views

www.spectracell.com/...calciumoncolorectaladenoma.pdf

inflammation cancer colorectal vitamin D3 CRP TNF IL-6 IL-1B IL-8

shared by Nathan Goodyear on 01 Feb 12 - No Cached

Nathan Goodyear on 01 Feb 12

Vitamin D3 shown to reduce CRP, TNF, IL-6, IL-1B, IL-8 in colorectal adenoma patients. This study supports the anti-inflammatory, anti-cancer benefits of vitamin D3.

<div class="cArrow"> </div><div class="cContentInner">Vitamin D3 shown to reduce CRP, TNF, IL-6, IL-1B, IL-8 in colorectal adenoma patients. This study supports the anti-inflammatory, anti-cancer benefits of vitamin D3.</div>

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JAMA Network | JAMA Internal Medicine | Vegetarian Dietary Patterns and the Risk of Col... - 0 views

archinte.jamanetwork.com/article.aspx

cancer diet nutrition vegetarian colon cancer colorectal cancer rectal cancer

shared by Nathan Goodyear on 16 Mar 15 - No Cached

Nathan Goodyear on 16 Mar 15

Vegeterian diet found to reduce colon, colorectal, and rectal cancer when compared to non-vegetarian diets.

<div class="cArrow"> </div><div class="cContentInner">Vegeterian diet found to reduce colon, colorectal, and rectal cancer when compared to non-vegetarian diets.</div>

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[Serum testosterone: a possible marker for colorectal cancer]. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8295527

Testosterone colon cancer colorectal cancer low Testosterone low T CEA men male hormone hormones

shared by Nathan Goodyear on 19 Nov 14 - No Cached

Nathan Goodyear on 19 Nov 14

Colorectal cancer associated with decreased Testosterone levels in men. This paper looked at total serum Testosterone. The authors proposed that CEA plus Testosterone could be used in follow up.

<div class="cArrow"> </div><div class="cContentInner">Colorectal cancer associated with decreased Testosterone levels in men. This paper looked at total serum Testosterone. The authors proposed that CEA plus Testosterone could be used in follow up.</div>

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Molecular Pathways: Estrogen Pathway in Colorectal Cancer - 0 views

clincancerres.aacrjournals.org/...5842

estrogen ER beta estrogen receptors hormones colon cancer colorectal cancer cancer

shared by Nathan Goodyear on 03 Feb 16 - No Cached

Nathan Goodyear on 03 Feb 16

ER-beta is lost in colorectal cancer

<div class="cArrow"> </div><div class="cContentInner">ER-beta is lost in colorectal cancer</div>

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PayPerView: A Randomized Study of Low-Dose Subcutaneous lnterleukin-2 Plus Melatonin ve... - 0 views

www.karger.com/...227465

IL-2 cancer melatonin colon cancer colorectal cancer

shared by Nathan Goodyear on 09 Nov 18 - No Cached

Nathan Goodyear on 09 Nov 18

Percent survival at 1 year was significantly increased in patients treated with immunotherapy than in those treated with supportive care alone (9/25 vs. 3/25, p < 0.05) in study which suggests that low-dose subcutaneous IL-2 plus melatonin may be effective as a second-line therapy to induce tumor regression and to prolong percent survival at 1 year in metastatic colorectal cancer patients progressing under 5-FU and folates

<div class="cArrow"> </div><div class="cContentInner"> Percent survival at 1 year was significantly increased in patients treated with immunotherapy than in those treated with supportive care alone (9/25 vs. 3/25, p < 0.05) in study which suggests that low-dose subcutaneous IL-2 plus melatonin may be effective as a second-line therapy to induce tumor regression and to prolong percent survival at 1 year in metastatic colorectal cancer patients progressing under 5-FU and folates</div>

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Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells | Br... - 0 views

www.nature.com/6605701

DCA dichloroacetate dichloracetic acid cancer colorectal cancer

shared by Nathan Goodyear on 08 Nov 18 - No Cached

Nathan Goodyear on 08 Nov 18

DCA induces apoptosis in colorectal cancer

<div class="cArrow"> </div><div class="cContentInner">DCA induces apoptosis in colorectal cancer</div>

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High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals corre... - 0 views

www.ncbi.nlm.nih.gov/...PMC2833250

colon cancer colorectal cancer cancer LPS lipopolysaccharides

shared by Nathan Goodyear on 11 Sep 17 - No Cached

Nathan Goodyear on 11 Sep 17

High TLR4 and MyD88 expression on the surface of colorectal cancer cells associated with increase liver mets potential and worsened prognosis. LPS works through TLR4 and MyD88.

<div class="cArrow"> </div><div class="cContentInner">High TLR4 and MyD88 expression on the surface of colorectal cancer cells associated with increase liver mets potential and worsened prognosis. LPS works through TLR4 and MyD88.</div>

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Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive... - 0 views

www.ncbi.nlm.nih.gov/...17520675

artesunate Wnt colorectal cancer

shared by Nathan Goodyear on 07 May 20 - No Cached

Nathan Goodyear on 07 May 20

artesunate inhibits colorectal cancer cells via Wnt pathway inhibition.

<div class="cArrow"> </div><div class="cContentInner">artesunate inhibits colorectal cancer cells via Wnt pathway inhibition.</div>

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Microbiota disbiosis is associated with colorectal cancer - 0 views

www.ncbi.nlm.nih.gov/...PMC4313696

cancer colon cancer colorectal cancer dysbiosis gut bacteria

shared by Nathan Goodyear on 10 Sep 17 - No Cached

Nathan Goodyear on 10 Sep 17

Study finds association between gut dysbiosis and colorectal cancer risk.

<div class="cArrow"> </div><div class="cContentInner">Study finds association between gut dysbiosis and colorectal cancer risk.</div>

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LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases β1 Inte... - 0 views

cancerres.aacrjournals.org/...1989

cancer colon cancer colorectal cancer LPS lipopolysaccharides

shared by Nathan Goodyear on 11 Sep 17 - No Cached

Nathan Goodyear on 11 Sep 17

cull culture study finds inhibition of LPS activated TLR4 in colorectal cancer cells decreased metastasis.

<div class="cArrow"> </div><div class="cContentInner">cull culture study finds inhibition of LPS activated TLR4 in colorectal cancer cells decreased metastasis.</div>

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Global patterns and trends in colorectal cancer incidence in young adults | Gut - 1 views

gut.bmj.com/...gutjnl-2019-319511

colorectal cancer

shared by Nathan Goodyear on 14 Sep 19 - No Cached

Nathan Goodyear on 14 Sep 19

Disturbing trend shows increasing colorectal cancer in younger patients.

<div class="cArrow"> </div><div class="cContentInner">Disturbing trend shows increasing colorectal cancer in younger patients.</div>

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Group items tagged

Sex Hormones and Colorectal Cancer: What Have We Learned So Far? - 0 views

http://www.turkjcancer.org/pdf/pdf_TJC_489.pdf - 0 views

JAMA Network | JAMA: The Journal of the American Medical Association | Low-Fat Dietary ... - 0 views

Reproductive History and risk of colorectal cancer in postmenopausal women - 0 views

A Case of Colorectal Cancer during Pregnancy: A Brief Review of the Literature - 0 views

American Journal of Gastroenterology - Abstract of article: Diagnostic Precision of Fec... - 0 views

http://www.scielo.oces.mctes.pt/pdf/ge/v13n3/v13n3a06 - 0 views

Exercise improves survival rates for colorectal cancer patients - Dana-Farber Cancer In... - 0 views

Immunohistochemical Expression of Estrogen and Progesterone Receptors in Human Colorect... - 0 views

Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorect... - 0 views

JAMA Network | JAMA Internal Medicine | Vegetarian Dietary Patterns and the Risk of Col... - 0 views

[Serum testosterone: a possible marker for colorectal cancer]. - PubMed - NCBI - 0 views

Molecular Pathways: Estrogen Pathway in Colorectal Cancer - 0 views

PayPerView: A Randomized Study of Low-Dose Subcutaneous lnterleukin-2 Plus Melatonin ve... - 0 views

Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells | Br... - 0 views

High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals corre... - 0 views

Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive... - 0 views

Microbiota disbiosis is associated with colorectal cancer - 0 views

LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases β1 Inte... - 0 views

Global patterns and trends in colorectal cancer incidence in young adults | Gut - 1 views

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