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Nathan Goodyear

Angiogenic Factors and Natural Killer (NK) Cells in the Pathogenesis of Preeclampsia - 0 views

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    Abnormal NK cell activity in the placenta plays a likely role in the development of preeclampsia. This proposes an immunologic role in the development of preeclampsia.  This process is similar to the literatures link between maternal NK and RPL.
Nathan Goodyear

Imbalance between Lipid Peroxidation and Antioxidant Status in Preeclampsia - 0 views

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    preeclampsia associated with oxidative stress.  Low levels of glutathione, vitamin C found in placentas of those with preeclampsia.  Implications for therapy?
Nathan Goodyear

Inflammatory responses to trivalent influenza virus ... [Vaccine. 2011] - PubMed - NCBI - 0 views

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    This article's conclusion fits the definition of insane. This article found that the flu vaccine in pregnant women found significant increased CRP, TNF-alpha, and IL-6 inflammatory biomarkers.  It is well recognized the impact of inflammation on health and in this case the developing baby.   For example, preeclampsia and preterm birth are inflammatory conditions.  Yet, ACOG has made recommmendations for all pregnant women to get the flu vaccine?!?! Here is their conclusion: "However, further research is needed to confirm that the mild inflammatory response elicited by vaccination is benign in pregnancy".  Take home, you are being studied to see the effects of the flu vaccine on you, if you are pregnant, and your developing child.  And who decides what "mild" is anyways.  If you develop preeclampsia and delivery early, where is the "mild" in that?
Nathan Goodyear

The role of decidual natural killer ce... [J Obstet Gynaecol Can. 2008] - PubMed - NCBI - 0 views

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    same NK link to RPL, linked to preeclampsia.  NK cells play important role in the development of the spiral arteries in the placenta. It has long been thought, that the placenta was the likely culprit in the development of preeclampsia
Nathan Goodyear

Preeclampsia is associated with a decrease in plasma coenzyme Q10 levels. - PubMed - NCBI - 0 views

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    Preeclampsia associated with lower CoQ10 levels in women.
Nathan Goodyear

Lipid-soluble antioxidants and pregnancy: maternal serum levels of coenzyme Q10, alpha-... - 0 views

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    Women with preeclampsia have lower CoQ10 levels compared to normal pregnant women.
Nathan Goodyear

Maternal Vitamin D Deficiency Increases the Risk of Preeclampsia - 0 views

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    vitamin D deficiency increases preeclampsia risk.  All pregnant women or women considering pregnancy should be evaluated for vitamin D deficiency.
Nathan Goodyear

Intake of Probiotic Food and Risk of Preeclampsia in Primiparous Women - 0 views

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    probiotics during pregnancy shown to reduce risk of preeclampsia
Nathan Goodyear

Co-occurrence of Cardiovascular and Prothrombotic Risk Facto... : Obstetrics & Gynecology - 0 views

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    preeclampsia should be a history marker that reveals increased cardiovascular disease (CVD).  
Nathan Goodyear

Clinical aspects of coenzyme Q10: an update. - PubMed - NCBI - 0 views

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    only abstract available here, but Coq10 found to decrease incidence of preeclampsia.
Nathan Goodyear

Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia. - PubM... - 0 views

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    200 mg CoQ10 found to decrease the risk of preeclampsia in those women at risk.
Nathan Goodyear

Studies on activity of... [J Huazhong Univ Sci Technolog Med Sci. 2004] - PubMed - NCBI - 0 views

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    As NK over activity has been shown to play in role in recurrent miscarriages, so it appears that loss if immune tolerance (elevated NK activity) may play a role in preeclampsia
Nathan Goodyear

Uterine and circulating natural killer cell... [J Reprod Immunol. 2011] - PubMed - NCBI - 0 views

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    women with RPL and preeclampsia carry same immunologic NK abnormalities.  Loss of immune tolerance, elevated maternal NK, shown to play role in both.
Nathan Goodyear

Maternal and Cord Steroid Sex Hormones, Angiogenic Factors and Insulin-like Growth Fact... - 0 views

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    Women with elevated androgens, Testosterone and androstenedione, are at higher risk of preeclampsia.  This translates to a higher risk of CVD in women later in life, post pregnancy.  This fits with other literature that CVD is linearly associated with a rising Testosterone.  This has been found in caucasian and black women.
Nathan Goodyear

Lower Rate of Preeclampsia After Antioxidant Supplementation in Pregnant Women with Low... - 0 views

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    antioxidant support in early pregnancy, including NAC, shown to reduce the incidence in pre-eclampsia
Nathan Goodyear

NK cells and pre-eclampsia. [Reprod Biomed Online. 2008] - PubMed - NCBI - 0 views

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    NK cells and their role in pre-eclampsia
Nathan Goodyear

Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia - 0 views

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    CoQ10 at 200 mg shown to significantly reduce the rate of pre-eclampsia in pregnant women.
Nathan Goodyear

ScienceDirect - Obstetrics & Gynecology : Low whole blood glutathione levels in pregnan... - 0 views

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    glutathione low in pregnancies complicated by PIH and HELLP syndrome. Every woman should have her detoxification capacity evaluated prior to pregnancy.
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