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Several interesting points about this article.  Cadmium is a non-carcinogen.  Cadmium acts through estrogen receptors.  Cd acts as an estrogen.  Second, melatonin inhibits ER alpha, which promotes inflammation and growth signaling.

If you are looking online for a children's dentist in Las Vegas, chances are you will find several sites for dentists in the area as well as general dental practitioners who can treat children. Now the question is-how do you choose?

This study found that high serum testosterone associated with a reduction of cardiovascular events in elderly men.  Studies have shown that low T is associated with increased cardiovascular mortality and in cardiovascular events, but this study takes it one step further: testosterone reduces those risks. 

study finds that HRT given as women transition through menopause has benefiical effect in people with Alzheimer's.  However, when given years later, after menopause, no benefit is found.  In fact, rates increased.  Several flaws with this study.  First, they used synthetic hormones, particularily progestins.  Second, there seems to be no thought that the interpretation of the signal  has changed.  For example, we know that when men have low T, their estrogen receptor status changes from ER beta to ER alpha, which is more proinflammatory.  Third, use bioidentical hormones and compare these to synthetic hormones.

hypothyroidism and hyponatremia is a rare finding; more commonly associated with severe hypothyroidism.  Co-exisitng medical complications need to be considered.

very good review of the differences in MS and hormones between the sexes.

Obesity trends continue in the wrong direction.  According to most recent stats, 40% of American women are obese and 35% of men are obese.  Severe obesity sits at 10% for American women.

Study finds that nebulizer glutathione in mild asthma induces bronchoconstriction.  This despite the knowledge that glutathione peroxidase activity is known to be depressed in those with asthma.  The severity of the asthma of the individuals included in this study might explain the finding.

Metabolic syndrome in men associated with progressive BPH and increased severity of LUTS.

Flat and/or abnormal diurnal cortisol patterns found to be associated with earlier mortality in breast cancer.  The flatter cortisol pattern, the earlier the mortality.  Several points here: this highlights the impact of cortisol on the immune system.  Second, this reveals how much of the research has moved to saliva as the gold standard.  This study by the NCI, used salivary cortisol to evaluate the risk of breast cancer survivors.

Review finds endocrine disruption from Organocholrides, also called persistent organohalogen pollutants. Common POP, would be DDE, DDT... This is a review of several cohorts, but this follows the rest of the literature that these environmental toxicants are endocrine disruptors.

this study of 40 obese patients found saliva cortisol testing less specific than urinary; but more than Dexamethasone suppression test.  The problem with this is several fold: first, this is done via ELIZA and not Mass Spec and second, 24 hour urine collection is hard to achieve in real life.

post-traumatic hypopituitarism is found in 40% of those with TBI.  The severity does correlate with the increased likelihood of developing PTHP.  Isolated deficiencies have been found in PTHP.

elevated cortisol levels found in moderate/severe PTSD in police officers.  Again, saliva testing was used for cortisol evaluation.

oxidative damage found to be present in early Alzheimer's disease.  This early mild cognitive impairment is the time for treatment to delay disease progression.  As this study points out, most studies up to this point have been done on individuals with late Alzheimer's disease.  This show that oxidative damage plays a prominent role in disease development.  This study found oxidative damage through several markers: lipid peroxides,isoprostanes, 8-hydroxy-2-deoxyguanosine...

Several flaws with this study. First, the majority of testing done in the meta-analysis was serum--unreliable.  Second, this study flies in the face of many other studies that have shown elevated estrogens contribute to low testosterone in men.  Third, this flies in the face of observation.  I see over and over again, by lowering a male's estrogen level, he in turn will start producing more Testosterone.  And finally, the environmental xenoestrogens have helped to contribute to a all time low of testosterone/infertility rate in men today.

this study revealed increased breast cancer risk in women on "estrogen" and "testosterone" therapy.  Now, several problems here: first, are these synthetic hormone or bioidentical.  Second, the dosages appear, in what is written, to be supra physiologic.  Third, giving supra physiologic estradiol and testosterone will obviously create imbalances and growth potential.  Fourth, how were the women evaluated prior to starting hormone therapy and then were they remonitered (unlikely), fifth, were hormone metabolites evaluated (too, also unlikely).  This study has serious flaws and very little can be extrapolated other than: don't take supra physiologic hormone levels without appropriate evaluation.  Enough said

Vitamin D deficiency found more prevalent in those children with critical illnesses; and with greater severity of illness.

to be read

Frightening statement from the American Heart Association.