SIRT1, known to reduce inflammatory signaling, found to help maintain circadian rhythm. Loss of the circadian rhythm is know to contribute to chronic disease. Likewise, SIRT1 has been shown to reduce inflammation, which will reduce disease. Is this their link?
this article looked at normal testosterone rhythm via saliva. Normal testosterone peaks in am and is lowest in pm. The normal testosterone rhythm decreases as a man ages. This is similar results as seen in serum.
Implantable cardioverter-defibrillators, additionally known as ICDs, are battery-powered gadgets positioned under the skin which could detect peculiar heart rhythms and supply an electric shock to restore a regular heartbeat. ICD procedure cost helps reduce the risk of sudden cardiac death and can be recommended for life-threatening rhythm irregularities due to myocardial infarction, cardiac arrest, or congenital heart disease.
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In this study, 104 breast cancer patients were evaluated with salivary cortisol. Those with flat cortisol rhythms had an earlier mortality rate. Also, NK cells were notably lower in the flat cortisol patients as well.
Flat and/or abnormal diurnal cortisol patterns found to be associated with earlier mortality in breast cancer. The flatter cortisol pattern, the earlier the mortality. Several points here: this highlights the impact of cortisol on the immune system. Second, this reveals how much of the research has moved to saliva as the gold standard. This study by the NCI, used salivary cortisol to evaluate the risk of breast cancer survivors.
granted, this comes from the American Journal of Primatology; but their conclusion says it all: "we recommend that saliva collection may be the moste effective method of measuring stress reactivity and as the potential to complement behavioral, cognitive, physiologic, and welfare studies".
LC-MS for salivary testosterone and DHEA validated. Also, T and DHEA were shown to have specific diurnal rhythms. Changes in levels were also followed after DHEA therapy.
India stands as a top destination for ICD implant procedures in India with high success rates from over 150,000 numerous cardiac strategies done each year. Dr. Anil Saxena's best ICD implantation surgeon in Fortis is known worldwide for the expert evaluation and treatment of patients with a variety of heart rhythm disorders.
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The best ICD implant procedure surgeon Fortis is a highly trained and dedicated healthcare professional specializing in heart rhythm management. Dr. Anil Saxena India has an international reputation for excellence in arrhythmia research and clinical arrhythmia management.
an association between disrupted nocturnal sleep and flattened diurnal cortisol rhythm in women with metastatic breast cancer
They suggest that the stress-buffering effects of sleep may be associated with improved parasympathetic tone and normalized cortisol patterns during the day.