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Nathan Goodyear

Exercise-associated hyponatremia: role of cytokines. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16843089

EAH exercise induced hyponatremia SIADH rhabdomyolysis hyponatremia endurance exercise endurance athletes endurance sports endurance athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    study links rhabdomyolysis to exercise induced hyponatremia.  This article links the depletion of glycogen to muscle release of IL-6 leading to increase in ECW and thus hyponatremia. The abstract discusses fluid restriction vs hypertonic 3% NaCL to reverse the more severe cases.  The first signs are of weight gain and thus weight should be monitored.  Decreased renal output is also associated with EAH.  Altered mental status is an early sign.
Nathan Goodyear

Exercise-associated hyponatremia. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19523574

exercise induced hyponatremia hyponatremia endurance athletes endurance sports endurance athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    hyponatremia due to exercise, or exercise induced hyponatremia, is multifactorial: over-hydration, poor renal clearance, SIADH thus inhibition of renal fluid clearance, and excessive Na loss through sweat.
Nathan Goodyear

Hypertonic (3%) sodium chloride for emergent treatment of exercise-... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17465635

endurance athletes exercise induced hyponatremia hyponatremia marathon runners athletes SIADH

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    event over hydration with under renal excretion can lead to hyponatremia.  SIADH and resultant increased ECW is involved.  Weight is an adequate means to evaluate--no weight loss and/or weight gain may suggest fluid overload and potential hyponatremia.
Nathan Goodyear

Hyponatremia - Endocrine and Metabolic Disorders - Merck Manuals Professional Edition - 0 views

www.merckmanuals.com/...hyponatremia

hyponatremia sodium

shared by Nathan Goodyear on 24 Nov 15 - No Cached
  • Nathan Goodyear on 24 Nov 15
     
    good review on hyponatremia
Nathan Goodyear

Hyponatremia and the Thyroid: Causality or Association? - 0 views

www.ncbi.nlm.nih.gov/...PMC4470237

hypothyroid hypothyroidism hyponatremia sodium thyroid

shared by Nathan Goodyear on 23 May 16 - No Cached
  • Nathan Goodyear on 23 May 16
     
    hypothyroidism and hyponatremia is a rare finding; more commonly associated with severe hypothyroidism.  Co-exisitng medical complications need to be considered.
Nathan Goodyear

Hyponatremia and Hypernatremia in the Elderly - American Family Physician - 0 views

www.aafp.org/...p3623.html

hyponatremia hypernatremia sodium

shared by Nathan Goodyear on 15 Aug 16 - No Cached
  • Nathan Goodyear on 15 Aug 16
     
    good review, though dated, of hyponatremia and hypernatremia in elderly.
Nathan Goodyear

Diagnosis and prevention of hyponatremia at an ultradistance triath... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10695851

hyponatremia triathlon endurance athletes endurance exercise endurance athletes weight

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    over hydration increases risk of hyponatremia.  Body weight is inversely associated with Na levels.  Weight evaluations are an appropriate means to evaluate.  Endurance triathlon athletes can lose up to 5% without any negative physiologic impact.
Nathan Goodyear

Management of Hyponatremia - American Family Physician - 0 views

www.aafp.org/...p2387.html

hyponatremia

shared by Nathan Goodyear on 24 Nov 15 - No Cached
  • SIADH is a diagnosis of exclusion
  • Nathan Goodyear on 24 Nov 15
     
    hyponatremia
Nathan Goodyear

Hyponatremia in cirrhosis: Pathophysiology and management - 0 views

www.ncbi.nlm.nih.gov/...PMC4363748

hyponatremia liver disease liver ascites

shared by Nathan Goodyear on 29 Aug 18 - No Cached
  • Nathan Goodyear on 29 Aug 18
     
    hyponatremia in liver disease with ascites.
Nathan Goodyear

Dysnatremia predicts a delayed recovery in collapsed ultramarathon ... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17620783

hyponatremia hypernatremia ultramarathon runners endurance athletes endurance exercise IV fluids athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    The majority of ultra marathon runners deal with hypernatremia versus hyponatremia.  The majority were normonatremic.  Intravenous fluids can more rapidly resolve hypernatremia versus oral liquids and serves as useful means to reduce hypernatremia when oral liquids proves intolerable.
Nathan Goodyear

Study of hematological and biochemical parameters in runners comple... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15523206

hyponatremia marathon runners endurance athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    No cases of hyponatremia noted in marathon runners.   Of note, over hydration was prevented through limited stations enroute.  NSAIDS negatively altered renal function
Nathan Goodyear

Serum biochemistry and morbidity among runners presenting for medic... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17620786

ultra-marathons endurance athletes IV fluids hyponatremia

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    Study looked at 9 athletes that were treated with IV fluids and found no significant morbidity with exercise associated hyponatremia.
Nathan Goodyear

Exertional Dysnatremia in Collapsed Marathon Runners - 0 views

ajcp.ascpjournals.org/...336.long

marathon runners hypernatremia hyponatremia endurance athletes endurance exercise endurance sports

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    Nice review of the treatment of hyper/hyponatremia with marathon runners.
Nathan Goodyear

Acute severe hypothyroidism is not associated with hyponatremia even with increased wat... - 0 views

bmcendocrdisord.biomedcentral.com/...1472-6823-13-27

hypothyroid hypothyroidism hyponatremia sodium cancer

shared by Nathan Goodyear on 23 May 16 - No Cached
  • Nathan Goodyear on 23 May 16
     
    study finds severe hypothyroidism that is abrupt is not associated with low sodium.
Nathan Goodyear

Fluid Balance During and After an Ironman Triathlon - ResearchGate - 0 views

www.researchgate.net/...and_After_an_Ironman_Triathlon

ironman triathlon endurance athletes athletes athlete endurance IV fluids

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    ultra distance triathlon athletes lost 2.5 kg weight during event.  Athletes that developed hyponatremia appeared to be fluid overloaded during event.
Nathan Goodyear

Intravenous Fluid Use in Athletes - 0 views

www.ncbi.nlm.nih.gov/...PMC3435915

IV intravenous fluid nutrition athletes athlete sports medicine sports exercise

shared by Nathan Goodyear on 13 Jan 15 - No Cached
  • Treatment of exercise-associated hyponatremia with hypertonic IV infusion to correct plasma sodium levels is also a standard and accepted use of IV fluid infusions
  • athletes who present for medical care with hypernatremia who cannot tolerate oral fluids can benefit from IV fluids
  • Vaporization of sweat accounts for 80% of heat loss in hot, dry atmospheric conditions. This mechanism of water loss is the major contributor for exercise-associated dehydration
  • ...30 more annotations...
  • The rate of water loss can be quantified through measurement of sweat rate
  • Pre- and postexercise body weight measurements are the most common means to estimate overall water loss but are condition specific
  • It appears that 1% to 2% body weight loss is well tolerated by the exercising athlete
  • Dehydration, defined as greater than 2% loss of body weight, can negatively affect performance
  • In highly trained endurance athletes, plasma volume and sodium serum concentration were preserved despite a 5% body weight loss
  • In Ironman triathletes, dehydration to 5% body weight loss did not correlate with occurrence of medical complications
  • hydration should begin hours prior to exercise, especially if known deficits are present, and fluids should be consumed at a slow, steady rate, with 5 to 7 mL/kg taken 4 hours prior to exercise
  • Sodium concentration did not produce significant changes in the rate of absorption but was primarily dependent on carbohydrate concentration
  • Replacing 150% of body weight loss over 60 minutes has been tolerated without complications
  • IV treatment of severe dehydration (>7% body weight loss), exertional heat illness, nausea, emesis, or diarrhea, and in those who cannot ingest oral fluids for other reasons, is clinically indicated
  • A recent survey of the National Football League teams revealed that 75% (24 of 32) of the teams utilized IV infusion of fluids for prehydration in at least some otherwise healthy individuals
  • In the National Football League, an average of 1.5 L of normal saline was administered approximately 2.5 hours prior to competition
  • after 2 hours of exercise, the rectal temperature was 0.6° higher in the group not receiving IV infusion. Also, stroke volume and cardiac output were 11% to 16% lower in the control group versus the IV infusion group.
  • Recent evidence suggests the etiology of EAMC is related to muscle fatigue and neuronal excitability
  • no correlation between hydration status or electrolyte concentrations with EAMC
  • there may be a subset of muscle cramping that is associated with a loss of both body fluid and sodium
  • Glycerol is the primary agent for oral hyperhydration
  • elevation of plasma volume by 200 to 300 mL via dextran infusion resulted in 15% increase in stroke volume, 4% increase in VO2 max, and an increase in the exercise time to fatigue
  • Neither the tonicity nor mode of hydration resulted in improved speed of rehydration, greater fluid retention, or improved performance
  • There are beneficial anecdotal reports of EAMC treatment in elite and professional-level athletes with IV hydration during the course of an event
  • Plasma volume was better restored during rehydration with IV fluids at preexercise and 5 minutes of exercise. At 15 minutes, there was no difference between IV and oral rehydration
  • More rapid restoration of plasma volume was accomplished in the IV treatment group with no advantages over oral rehydration in physiological strain, heat tolerance, ratings of perceived effort, or thermal sensations
  • No difference was found in exercise time to exhaustion. IV and oral rehydration methods were equally effective. Heart rates were statistically higher in the oral rehydration group through 75 minutes of exercise, and there were higher increases in norepinephrine plasma concentrations
  • No significant differences between the groups were found for time to recovery, number of days with pain, number of days with stiffness, sleep disturbance, fatigue, rectal temperature, and loss of appetite
  • The current data suggest that IV rehydration is faster than oral
  • There may be physiological benefits of decreased heart rate and norepinephrine in athletes rehydrated via IV route
  • Postexercise blood 1 hour and 24 hours showed no differences in circulating myoglobin or creatine kinase
  • The use of IV fluid may be beneficial for a subset of fluid sensitive athletes
  • this should be reserved for high-level athletes with strong histories of symptoms in well-monitored settings.
  • Volume expanders may also be beneficial for some athletes
  • Nathan Goodyear on 13 Jan 15
     
    to be read
Nathan Goodyear

Secondary Adrenal Insufficiency: An Overlooked Cause of Hyponatremia - 0 views

www.ncbi.nlm.nih.gov/...PMC4330026

adrenal insufficiency hyponatraemia sodium ADH cortisol CRH ACTH

shared by Nathan Goodyear on 25 Sep 17 - No Cached
  • Nathan Goodyear on 25 Sep 17
     
    Good case review of secondary adrenal insufficiency.  A common cause of low sodium and needs to be considered in elderly patients.  Also, low cortisol is associated with increased ADH.  In the case of adrenal insufficiency, the negative feed back of cortisol to the HPA is lost and recreation of CRH, which is an ADH secretagogue, will increase ADH secretion.
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