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Vagal Regulation, Cortisol, and Sleep Disruption in Women with Metastatic Breast Cancer - 0 views

www.ncbi.nlm.nih.gov/...PMC2576311

saliva salivary cortisol test testing evaluation hormone hormones sleep breast cancer metastatic BHRT

shared by Nathan Goodyear on 28 Nov 11 - No Cached

an association between disrupted nocturnal sleep and flattened diurnal cortisol rhythm in women with metastatic breast cancer
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They suggest that the stress-buffering effects of sleep may be associated with improved parasympathetic tone and normalized cortisol patterns during the day.
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Nathan Goodyear on 28 Nov 11

women with metastatic breast cancer shown to have more disruption in cortisol pattern and thus dysfunctional sleep. This has implications on survival.

<div class="cArrow"> </div><div class="cContentInner">women with metastatic breast cancer shown to have more disruption in cortisol pattern and thus dysfunctional sleep. This has implications on survival.</div>

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Arch Neurol -- Abstract: Prefrontal Cortex and Executive Function Impairments in Primar... - 0 views

archneur.ama-assn.org/...1447

chemotherapy brain fog side effects breast cancer executive function

shared by Nathan Goodyear on 13 Dec 11 - No Cached

Nathan Goodyear on 13 Dec 11

Chemotherapy patients often complain of "chemo brain". This article confirms significant reduction in prefrontal cortical activity, thus supporting brain dysfunction, "brain fog", as a result of chemotherapy.

<div class="cArrow"> </div><div class="cContentInner">Chemotherapy patients often complain of "chemo brain". This article confirms significant reduction in prefrontal cortical activity, thus supporting brain dysfunction, "brain fog", as a result of chemotherapy.</div>

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CNS Spectrums: Inflammation, Glutamate, and Glia in Depression: A Literature Review - 0 views

www.cnsspectrums.com/...articledetail.aspx

inflammation depression excitotoxicity glutamate glutamic acid mood disorders

shared by Nathan Goodyear on 20 Jan 12 - No Cached

Nathan Goodyear on 20 Jan 12

inflammation, glutamate excitotoxicity and depression. A very nice review of how inflammation can remotely contribute to other arenas of dysfunction, ie. depression.

<div class="cArrow"> </div><div class="cContentInner">inflammation, glutamate excitotoxicity and depression. A very nice review of how inflammation can remotely contribute to other arenas of dysfunction, ie. depression.</div>

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Obesity is associated with macrophage accumulation in adipose tissue - 0 views

www.ncbi.nlm.nih.gov/...PMC296995

obesity inflammation overweight weight-loss WAT white adipose tissue M1 macrophages

shared by Nathan Goodyear on 16 Jan 12 - No Cached

Nathan Goodyear on 16 Jan 12

obesity is associated with dysfunctional immune response to adipose tissue. The cause is inflammation from White adipose tissue resultant in increased recruitment of macrophages and resultant further inflammation. M1 macrophages are the predominate culprit.

<div class="cArrow"> </div><div class="cContentInner">obesity is associated with dysfunctional immune response to adipose tissue. The cause is inflammation from White adipose tissue resultant in increased recruitment of macrophages and resultant further inflammation. M1 macrophages are the predominate culprit.</div>

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Multiple Sclerosis is not a Disease of the Immune System - 0 views

dl.dropbox.com/...MS_Not_an_Immune_Disease.pdf

MS multiple sclerosis inflammation inflammatory condition disease lipid metabolism autoimmune

shared by Nathan Goodyear on 03 Jan 12 - No Cached

Nathan Goodyear on 03 Jan 12

good read on an alternate hypothesis of the pathophysiology of MS. THe author proposes that MS is an inflammatory induced dysfunction of lipid metabolism. This is in contrast to the current held dogma that MS is an autoimmune disease.

<div class="cArrow"> </div><div class="cContentInner">good read on an alternate hypothesis of the pathophysiology of MS. THe author proposes that MS is an inflammatory induced dysfunction of lipid metabolism. This is in contrast to the current held dogma that MS is an autoimmune disease.</div>

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Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with... - 0 views

www.ncbi.nlm.nih.gov/...11241044

ASD autism inflammation children Lymphoid nodular hyperplasia LNH regressive

shared by Nathan Goodyear on 30 Jan 12 - No Cached

Nathan Goodyear on 30 Jan 12

Study shows that gastrointestinal epithelial dysfunction is found in autism. This would play a critical role in systemic inflammation and would contribute to ASD symptoms through the gut-brain connection.

<div class="cArrow"> </div><div class="cContentInner">Study shows that gastrointestinal epithelial dysfunction is found in autism. This would play a critical role in systemic inflammation and would contribute to ASD symptoms through the gut-brain connection.</div>

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Effect of Exogenous Thyroid Hormone Intake on the Interpretation of Serum TSH Test Results - 0 views

www.thyroidscience.com/...warmingham.7.18.10.pdf

TSH thyroid hypothyoidism Warmingham hypothesis hypothyroid

shared by Nathan Goodyear on 02 Feb 12 - No Cached

Nathan Goodyear on 02 Feb 12

TSH is promoted as the test of choice to diagnosis and monitor thyroid dysfunction. However, Warmingham hypothesis, would suggest otherwise.

<div class="cArrow"> </div><div class="cContentInner">TSH is promoted as the test of choice to diagnosis and monitor thyroid dysfunction. However, Warmingham hypothesis, would suggest otherwise. </div>

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Hypothalamopituitary Dysfunction Following Traumatic Brain Injury and Aneurysmal Subara... - 0 views

jama.ama-assn.org/...1429.full

TBI traumatic brain injury pituitary HPA hormone hormones hypothalamic dysfunction

shared by Nathan Goodyear on 03 Feb 12 - No Cached

Nathan Goodyear on 03 Feb 12

TBI results in altered pituitary function. This study reviewed research articles published over a 7 year time (2000-2007).

<div class="cArrow"> </div><div class="cContentInner">TBI results in altered pituitary function. This study reviewed research articles published over a 7 year time (2000-2007).</div>

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Thyroid function and thyroid hormone metabol... [Klin Wochenschr. 1981] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7241955

hypothyroid hypothyroidism TSH T3 syndrome low aging thyroid hormone

shared by Nathan Goodyear on 07 Feb 12 - No Cached

Nathan Goodyear on 07 Feb 12

This study doesn't find evidence of low t3-syndrome, but suggests the impairment of TSH secretion (low TSH)is the first potential sign of thyroid dysfunction.

<div class="cArrow"> </div><div class="cContentInner">This study doesn't find evidence of low t3-syndrome, but suggests the impairment of TSH secretion (low TSH)is the first potential sign of thyroid dysfunction.</div>

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Gastrointestinal abnormalities in children with autistic disorder - 0 views

mercola.fileburst.com/...4.Horvath%201.pdf

shared by Nathan Goodyear on 29 Jan 12 - No Cached

Nathan Goodyear on 29 Jan 12

study shows that gastrointestinal dysfunction, reflux esophagitis and disaccharide malabsorption, found in children with autism. This confirms the gut-brain link component of autism

<div class="cArrow"> </div><div class="cContentInner">study shows that gastrointestinal dysfunction, reflux esophagitis and disaccharide malabsorption, found in children with autism. This confirms the gut-brain link component of autism</div>

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Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in ... - 0 views

mercola.fileburst.com/...Ileal%20cytokines.pdf

ASD autism inflammation

shared by Nathan Goodyear on 29 Jan 12 - No Cached

Nathan Goodyear on 29 Jan 12

immune dysfunction found in children with autism. This again, suggests a gut-brain link in autism.

<div class="cArrow"> </div><div class="cContentInner">immune dysfunction found in children with autism. This again, suggests a gut-brain link in autism.</div>

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Colonic CD8 and γδ T-cell infiltration with epithelial damage in children wit... - 0 views

mercola.fileburst.com/...5.Furlano.pdf

autism ASD colitis pediatrics children

shared by Nathan Goodyear on 29 Jan 12 - No Cached

Nathan Goodyear on 29 Jan 12

Gut dysfunction, lymphocytic colitis, found in children with autism.

<div class="cArrow"> </div><div class="cContentInner">Gut dysfunction, lymphocytic colitis, found in children with autism.</div>

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Dysregulated Innate Immune Responses in Young Children with Autism Spectrum Disorders: ... - 0 views

mercola.fileburst.com/...europsych%20--%20Jyonouchi.pdf

autism ASD LPS inflammation innate immune system gut gastrointestinal

shared by Nathan Goodyear on 29 Jan 12 - No Cached

Nathan Goodyear on 29 Jan 12

Dysfunctions of the innate immune system, in the gastrointestinal system, in children with autism found. LPS found to be involved. Again, revealing a gut-brain connection in autism.

<div class="cArrow"> </div><div class="cContentInner">Dysfunctions of the innate immune system, in the gastrointestinal system, in children with autism found. LPS found to be involved. Again, revealing a gut-brain connection in autism.</div>

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Autistic enterocolitis: Fact or fiction? - 0 views

mercola.fileburst.com/...0ot%20Fiction%20Fed%202009.pdf

autism ASD inflammation gastrointestinal

shared by Nathan Goodyear on 29 Jan 12 - No Cached

Nathan Goodyear on 29 Jan 12

report of 2 cases studies that find link between autism and gastrointestinal inflammation. Again, suggestion some immune system dysfunction in the gastrointestinal system in some children with autism

<div class="cArrow"> </div><div class="cContentInner">report of 2 cases studies that find link between autism and gastrointestinal inflammation. Again, suggestion some immune system dysfunction in the gastrointestinal system in some children with autism</div>

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Brazilian Journal of Medical and Biological Research - Is the infertility in hypothyroi... - 0 views

www.scielo.br/scielo.php

functional hypothyroidism prolactin elevated gonadotropins infertility LH FSH

shared by Nathan Goodyear on 17 Nov 11 - No Cached

Nathan Goodyear on 17 Nov 11

functional hypothyroidism associated with elevated prolactin levels and thus gonadotropin dysfunction and infertility

<div class="cArrow"> </div><div class="cContentInner">functional hypothyroidism associated with elevated prolactin levels and thus gonadotropin dysfunction and infertility</div>

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Nutrition Journal | Full text | Homocysteine and reactive oxygen species in metabolic s... - 0 views

www.nutritionj.com/4

homocysteine atherogenesis CVD metabolic syndrome metabolic syndrome

shared by Nathan Goodyear on 23 Jul 12 - No Cached

Nathan Goodyear on 23 Jul 12

homocysteine contributes to atherogenesis and CVD via: increased ROS, induces endothelial dysfunction, increases platelete adhesion and thrombosis, increases smooth muscle cell proliferation, endothelial cell cytotoxicity, increases LDL oxidation, vasoconstriction, increased MCP-1 and IL-8, and induces endothelial HMG CoA reductase.

<div class="cArrow"> </div><div class="cContentInner">homocysteine contributes to atherogenesis and CVD via: increased ROS, induces endothelial dysfunction, increases platelete adhesion and thrombosis, increases smooth muscle cell proliferation, endothelial cell cytotoxicity, increases LDL oxidation, vasoconstriction, increased MCP-1 and IL-8, and induces endothelial HMG CoA reductase.</div>

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Testosterone and the aging male: to treat or not to treat? - 0 views

www.hormonebalance.org/...ain%2010%20TRT%20men%20Mat.pdf

testosterone low T therapy treatment men hormone hormones

shared by Nathan Goodyear on 20 Feb 12 - No Cached

Nathan Goodyear on 20 Feb 12

nice review of low Testosterone, the metabolic dysfunction as a result of low T, Testosterone therapy, and things to consider when supporting Testosterone.

<div class="cArrow"> </div><div class="cContentInner">nice review of low Testosterone, the metabolic dysfunction as a result of low T, Testosterone therapy, and things to consider when supporting Testosterone.</div>

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Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fa... - 0 views

diabetes.diabetesjournals.org/...1470.full

metabolic metabolic endotoxemia obesity overweight LPS inflammation flora diet

shared by Nathan Goodyear on 29 Feb 12 - No Cached

Nathan Goodyear on 29 Feb 12

2008 article from diabetes. This article supports metabolic endotoxemia arising out of the gut. High fat diet intake results in disrupted gut flora, resulting in increrased LPS release, resulting in inflammation, leads to leaky gut, systemic endotoxemia, inflammation, and thus metabolic dysfunction: see obesity, DM..

<div class="cArrow"> </div><div class="cContentInner">2008 article from diabetes. This article supports metabolic endotoxemia arising out of the gut. High fat diet intake results in disrupted gut flora, resulting in increrased LPS release, resulting in inflammation, leads to leaky gut, systemic endotoxemia, inflammation, and thus metabolic dysfunction: see obesity, DM..</div>

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JAMA Network | Archives of Neurology | Insulin Resistance in Cognitive ImpairmentThe In... - 0 views

archneur.jamanetwork.com/article.aspx

IR insulin resistance brain neurodegenerative disorders Alzheimer's disease obesity neurology dementia

shared by Nathan Goodyear on 11 Jun 12 - No Cached

Nathan Goodyear on 11 Jun 12

insulin resistance shown to play a role in cognitive impairment. Rising Insulin resistance is not just associated with obesity, but also brain dysfunction similar to that in strokes. This indicates a vascular component in the cognitive function. The same rise in obesity will likely result in a rise in neurodegenerative disorders.

<div class="cArrow"> </div><div class="cContentInner">insulin resistance shown to play a role in cognitive impairment. Rising Insulin resistance is not just associated with obesity, but also brain dysfunction similar to that in strokes. This indicates a vascular component in the cognitive function. The same rise in obesity will likely result in a rise in neurodegenerative disorders.</div>

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Effects of selective serotonin reuptake inhibitors o... [Thyroid. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19583486

thyroid SSRI antidepressants

shared by Nathan Goodyear on 09 Sep 13 - No Cached

Nathan Goodyear on 09 Sep 13

Interesting study. They found a "significant reduction of T(3) after 15 and 30 days" with SSRI use, yet their conclusion is SSRI is safe in hypothyroid. The take is that part of the weight gain associated with SSRI use is through dysfunction of thyroid hormone production as the effects were also found with T4.

<div class="cArrow"> </div><div class="cContentInner">Interesting study. They found a "significant reduction of T(3) after 15 and 30 days" with SSRI use, yet their conclusion is SSRI is safe in hypothyroid. The take is that part of the weight gain associated with SSRI use is through dysfunction of thyroid hormone production as the effects were also found with T4.</div>

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