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PLOS ONE: Healthy Lifestyles Reduce the Incidence of Chronic Diseases and Dementia: Evi... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0081877 lifestyle BMI overweigh obesity smoking diet nutrition dementia chronic disease
shared by Nathan Goodyear on 18 Dec 13 - No Cached
  • Nathan Goodyear on 18 Dec 13
     
    Despite evidence that non-smoking, normal BMI, regular exercise, high fruit/vegetable intake and low/moderate alcohol intake, less than 1% of men change lifestyle.  Translation:  many don't want health even when presented with evidence of its benefits and the means to achieve it.   This study found a decrease in cognitive decline in individuals undergoing these lifestyle changes.
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Alcohol intake and risk of dementia. [J Am Geriatr Soc. 2004] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15066068 wine resveratrol alcohol dementia Alzheimer's disease
shared by Nathan Goodyear on 07 Nov 13 - No Cached
  • Nathan Goodyear on 07 Nov 13
     
    Moderate wine intake daily associated with a lower risk of Alzheimer's disease in the elderly.  But, only in those without the APOE epsilon-4 allele.
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Mediterranean diet, cognitive function, and dementia: a systematic review. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23680940 nutrition diet Mediterranean diet dementia alzheimer's disease cognition brain brain health
shared by Nathan Goodyear on 21 May 17 - No Cached
  • Nathan Goodyear on 21 May 17
     
    review finds Mediterranean diet may slow cognitive decline and decrease risk of Alzheimer's disease.
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Mediterranean Diet, Cognitive Function, and Dementia: A Systematic Review of the Evidence - 0 views

advances.nutrition.org/...889.abstract mediterranean diet nutrition brain health cognition dementia diet
shared by Nathan Goodyear on 21 May 17 - No Cached
  • Nathan Goodyear on 21 May 17
     
    review finds Mediterranean diet associated with improved cognitive function and possible delay in cognitive decline.
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Age-Related White Matter Changes - 0 views

www.hindawi.com/...617927 dementia white matter dementia brain white matter
shared by Nathan Goodyear on 14 Jun 17 - No Cached
  • Nathan Goodyear on 14 Jun 17
     
    Good review of White matter changes associated with aging and associated risks and treatments.
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Sex hormones and cognitive decline ... [Psychoneuroendocrinology. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18845400 men estrogen estradiol estrone dementia cognitive decline low T low testosterone hormones hormone
shared by Nathan Goodyear on 30 Apr 13 - No Cached
  • Nathan Goodyear on 30 Apr 13
     
    increased estradiol and estrone levels in men associated with cognitive decline.  This was distinct from age, CVD, and APOE genotype.  This points to a clear association between increased aromatase activity and inflammation that contributes to cognitive decline in men.
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Neuroprotective lifestyles and the aging brain - 0 views

www.neurology.org/...1802.abstract exercise elderly dementia neuroprotection neurology aging brain lifestyles
shared by Nathan Goodyear on 01 Nov 12 - No Cached
  • Nathan Goodyear on 01 Nov 12
     
    exercise limits brain atrophy in the elderly.  Exercise provides neuroprotection.
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Frontiers | Adherence to a Mediterranean-Style Diet and Effects on Cognition in Adults:... - 0 views

journal.frontiersin.org/...full nutrition diet mediterranean diet brain alzheimer's disease Alzheimers memory
shared by Nathan Goodyear on 26 Sep 16 - No Cached
  • adherence to a MedDiet pattern is associated with less cognitive decline, dementia, or AD
  • higher adherence to a MedDiet was related to either slowing the rate of cognitive decline, minimizing the conversion to AD or improving the cognitive function
  • The more specific cognitive domains that improved with MedDietS were memory, delayed recognition, executive function, long-term working memory, and visual constructs
  • Nathan Goodyear on 26 Sep 16
     
    Mediterranean diet found to improve cognition and slow progression and/or risk of Alzheimer's disease.
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Omega-3 polyunsaturated fatty acid suppl... [J Nutr Health Aging. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21267519 omega-3 cognitive decline Alzheimer's disease dementia aging brain health
shared by Nathan Goodyear on 17 Nov 11 - No Cached
  • Nathan Goodyear on 17 Nov 11
     
    omega-3 supplementation shown to slow cognitive decline in study of elderly Chinese women and men
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Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 trans... - 0 views

www.ncbi.nlm.nih.gov/...PMC2725435 IV vitamin C brain Alzheimer's disease dementia cognition cognitive function learning
shared by Nathan Goodyear on 08 Mar 12 - No Cached
  • Nathan Goodyear on 08 Mar 12
     
    IV vitamin C improves cognitive function in mice model.  
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JAMA Network | Archives of Neurology | Insulin Resistance in Cognitive ImpairmentThe In... - 0 views

archneur.jamanetwork.com/article.aspx IR insulin resistance brain neurodegenerative disorders Alzheimer's disease obesity neurology dementia
shared by Nathan Goodyear on 11 Jun 12 - No Cached
  • Nathan Goodyear on 11 Jun 12
     
    insulin resistance shown to play a role in cognitive impairment.  Rising Insulin resistance is not just associated with obesity, but also brain dysfunction similar to that in strokes.  This indicates a vascular component in the cognitive function.  The same rise in obesity will likely result in a rise in neurodegenerative disorders.
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Lifelong Estrogen Exposure and Memory in Older Postmenopausal Women - Journal of Alzhei... - 0 views

iospress.metapress.com/...q781740m46771311 estrogen alzheimer dementia postmenopause women hormone hormones memory
shared by Nathan Goodyear on 10 Sep 13 - No Cached
  • Nathan Goodyear on 10 Sep 13
     
    Study finds suggestion of cognitive protection by enduring estrogen exposure.  Interesting, that estrogen seems to protect against cognitive decline in women, yet increases cognitive decline in men.
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Lower-But-Normal Serum TSH level Is Associated With the Development or Progression of C... - 0 views

press.endocrine.org/...jc.2013-3385 TSH cognition dementia elderly aging brain hormone hormones functional hypothyroidism
shared by Nathan Goodyear on 03 Mar 14 - No Cached
  • Nathan Goodyear on 03 Mar 14
     
    This study points to an association between a low-normal TSH and cognitive decline in the elderly.  An association is not causative, but functional hypothyroidism does result in cognitive impairment, so the association would logically fit.  The results of this study do as well.
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Decreased Accumulation of Subcellular Amyloid-β with Improved Mitochondrial F... - 0 views

iospress.metapress.com/...jp517wt324588874 Huperzine-A Huperzine Alzheimer's alzheimer's disease Alzheimers dementia mitochondria Beta-amyloid protein
shared by Nathan Goodyear on 09 Apr 14 - No Cached
  • Nathan Goodyear on 09 Apr 14
     
    Huperzine A, a natural acetylcholinesterase inhibitor, provides neuroprotection through increase mitochondrial function and decrease in accumulated amyloid Beta protein.
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http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.po... - 0 views

www.plosone.org/...fetchObject.action alzheimer's disease Alzheimer's disease Alzheimers dementia huperzine A
shared by Nathan Goodyear on 30 Sep 14 - No Cached
  • Nathan Goodyear on 30 Sep 14
     
    Another meta-analysis, this time of 20 studies, finds benefit of huperzine A in the treatment of Alzheimer's disease.
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Antipsychotic drug use and mortality in older adul... [Ann Intern Med. 2007] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...17548409 anti-psychotics neuroleptics
shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Atypical antipsychotic use is associated with an increased risk for death compared with nonuse among older adults with dementia
  • Nathan Goodyear on 10 Dec 10
     
    up to 1.55 x increase risk of death with antipsychotic use
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Coenzyme Q10 in neuromuscular and neurodegenerativ... [Curr Drug Targets. 2010] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...20017723 CoQ10 Alzheimer's Parkinson's ALS Dementia Neurodegenerative disease
shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • a deficit in CoQ10 status has been determined in a number of neuromuscular and neurodegenerative disorders
  • A secondary loss of CoQ10 status following HMG-Coa reductase inhibitor (statins) treatment has be implicated in the pathophysiology of the myotoxicity associated with this pharmacotherapy
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 contributes to neurodegenerative disease, Parkinson's, Alzheimer's, ALS..., in some
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