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Nathan Goodyear

Coenzyme Q10 reverses pathological phenotype and r... [Neurology. 2001] - PubMed result - 0 views

  • The authors conclude that muscle CoQ10 deficiency can be corrected by supplementation of CoQ10, which appears to stimulate mitochondrial proliferation and to prevent apoptosis.
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    CoQ10 supplementation shown to resolve familial CoQ10 deficiency
Nathan Goodyear

American College of Cardiology Foundation | Journal of the American College of Cardiolo... - 0 views

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    Small study, but well designed study shows that statins inhibit CoQ10 mediated oxidative phosphorylation through decrease in CoQ10.  This points directly at a decrease in mitochondrial function as a result of statin therapy.
Nathan Goodyear

Coenzyme Q10 in pregnancy. - PubMed - NCBI - 0 views

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    low CoQ10 associated with spontaneous miscarriage in abstract.  The authors of this paper found CoQ10 levels increased throughout "normal pregnancy".  Only abstract available here.
Nathan Goodyear

Effect of Coenzyme Q10 on Th1/Th2 Paradigm in Females with Idiopathic Recurrent Pregnan... - 0 views

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    CoQ10 reduced Th1 inflammatory cytokines in those women with recurrent early pregnancy loss.  CoQ10 specifically, reduced IFN-gamma.
Nathan Goodyear

Nutrition Journal | Full text | Effects of coenzyme Q10 supplementation (300 ... - 0 views

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    CoQ10 reduced inflammatory cytokines IL-6 and TNF-alpha.  CoQ10 also increased SOD, catalase, and glutathione perioxidase.  The duration of therapy was quite short--12 weeks.  The patients included in the study had pre-existing CAD.
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    study finds prolonged exposure to estrogen associated with increased colorectal cancer risk in postmenopausal women. So many unanswered questions. What was the ER status of these patients? What was the weight of these patients? One cannot simply compare estrogen exposure to colorectal cancer risk and say aha! What is the environment of the individual(s)?!Thanks visit; blog.hoop.la
Nathan Goodyear

Coenzyme Q10 in neuromuscular and neurodegenerativ... [Curr Drug Targets. 2010] - PubMe... - 0 views

  • a deficit in CoQ10 status has been determined in a number of neuromuscular and neurodegenerative disorders
  • A secondary loss of CoQ10 status following HMG-Coa reductase inhibitor (statins) treatment has be implicated in the pathophysiology of the myotoxicity associated with this pharmacotherapy
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    CoQ10 contributes to neurodegenerative disease, Parkinson's, Alzheimer's, ALS..., in some
Nathan Goodyear

Effects of CoQ10 supplementation and swimm... [Bratisl Lek Listy. 2012] - PubMed - NCBI - 0 views

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    CoQ10 along with swimming training, inhibited lipid per oxidation and DNA damage.
Nathan Goodyear

The evidence basis for coenzyme Q therapy in oxida... [Mitochondrion. 2007] - PubMed re... - 0 views

  • In some mitochondrial diseases and other commoner disorders such as cardiac disease and Parkinson's disease low mitochondrial or tissue levels of CoQ10 have been demonstrated providing an obvious rationale for supplementation
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    Coq10 in Parkinson's disease and cardiac disease beneficial
Nathan Goodyear

Coenzyme Q10: a review of its promise as a neuropr... [CNS Spectr. 2007] - PubMed result - 0 views

  • Experimental studies in animal models suggest that CoQ10 may protect against neuronal damage that is produced by ischemia, atherosclerosis and toxic injury.
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    CoQ10 and neuroprotection
Nathan Goodyear

Coenzyme Q10 administration and its potential for ... [Biofactors. 1999] - PubMed result - 0 views

  • hese studies therefore raise the prospect that administration of CoQ10 may be useful for the treatment of neurodegenerative diseases.
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    CoQ10 may be used to slow progression of neurodegenerative diseases such as Alzheimers, Parkinson's, ALS...
Nathan Goodyear

Coenzyme Q10 as a possible treatment for neurodege... [Free Radic Res. 2002] - PubMed r... - 0 views

  • CoQ10 can significantly extend survival, delay motor deficits and delay weight loss and attenuate the development of striatal atrophy in a transgenic mouse model of HD
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    CoQ10 shown to shown to slow progression of the neurodegenerative disease: Huntington's disease
Nathan Goodyear

Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation ... - 0 views

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    good review on CoQ10.  The abstract is the only format available on line to the general public.
Nathan Goodyear

ESC | Congresses | HEART FAILURE 2013 | Scientific Programme - 0 views

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    CoQ10 in those with prior MIs, found to have reduced hospital readmission, less heart failure, and lower cardiovascular death.  Enough said.
Nathan Goodyear

Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis - 0 views

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    Meta-analysis shows that coQ10 "may" improve heart function in those with CHF.
Nathan Goodyear

Positive correlation between maternal serum coenzyme Q10 levels and infant birth weight... - 0 views

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    low serum CoQ10 maternal levels associated with low birth weight.
Nathan Goodyear

Maternal plasma and amniotic fluid coenzyme Q10 levels in preterm and term gestations: ... - 0 views

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    Pilot study and only abstract available here: Low CoQ10 levels found in amniotic sample in preterm delivered pregnancies; not difference was found in serum levels.
Nathan Goodyear

Clinical aspects of coenzyme Q10: an update. - PubMed - NCBI - 0 views

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    only abstract available here, but Coq10 found to decrease incidence of preeclampsia.
Nathan Goodyear

Preeclampsia is associated with a decrease in plasma coenzyme Q10 levels. - PubMed - NCBI - 0 views

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    Preeclampsia associated with lower CoQ10 levels in women.
Nathan Goodyear

Lipid-soluble antioxidants and pregnancy: maternal serum levels of coenzyme Q10, alpha-... - 0 views

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    Women with preeclampsia have lower CoQ10 levels compared to normal pregnant women.
Nathan Goodyear

Plasma coenzyme Q10 is increased during gestational diabetes. - PubMed - NCBI - 0 views

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    CoQ10 levels elevated in women with gestational diabetes.  The authors proposed that this was an adaptation to increased oxidative stress.
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