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Puedo Beber Alcohol con Creatinina 150 y GFR 30 - 0 views

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    El alcohol aparece comúnmente en nuestra vida diaria, pero el alcohol causará algunos problemas de salud, incluso para las personas de salud.Si los pacientes tienen creatinina 150 y GFR 30, tenían mejor prestar atención al consumo de alcohol.
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    El alcohol aparece comúnmente en nuestra vida diaria, pero el alcohol causará algunos problemas de salud, incluso para las personas de salud.Si los pacientes tienen creatinina 150 y GFR 30, tenían mejor prestar atención al consumo de alcohol.
Nathan Goodyear

Effects of Alcohol Consumption on Plasma and Urinary Hormone Concentrations in Premenop... - 0 views

  • This study has shown increases in total estrogen levels and amount of bioavailable estrogens in association with alcohol consumption in pre-menopausal women.
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    alcohol increases estrogen production in pre-menopausal women;  implications that alcohol intake increases risk of estrogen sensitive cancers
Nathan Goodyear

Urinary estrogen metabolites in women at high risk for breast cancer - 0 views

  • obesity has also been linked to preferential estrogen metabolism via the 16-alpha-hydroxylation pathway; thus, a prediction of the mechanism by which obesity could increase breast cancer risk would be through a lowering of the 2:16 ratio in favor of the 16 pathway
  • increased BMI was associated with a lower 2:16 OHE ratio
  • Our data show a significant association between alcohol use, defined as at least one drink per day or an average of seven per week, and 2:16 OHE ratio
  • ...10 more annotations...
  • An alcohol-induced rise in estrogens as a consequence of alcohol catabolism in the liver has been reported
  • The only study that looked at the association between alcohol and wine consumption in healthy women did not report a clear association
  • smoking has been reported to increase induction of the 2-hydroxylation metabolic pathway (24). However, the few epidemiological studies conducted on healthy women showed no difference in estrogen metabolites with smoking status (22) or smoking dose (20), in line with our findings.
  • Family history of a first-degree family member with breast cancer confers a 2- to 4-fold risk of developing breast cancer
  • 16% of breast cancers are due to unidentified hereditary factors
  • Estrogen metabolism occurs through enzymes whose activity is determined by the presence of specific genetic polymorphisms, thus can be defined as unique to each individual.
  • the metabolism is also influenced by a number of environmental factors, which change over a lifetime
  • significantly lower 2:16 OHE ratio in women who have known breast cancer risk factors compared with healthy women
  • There was an additional significant association specifically with BMI and alcohol use, which also supports the evidence that these factors affect estrogen metabolism
  • Profiling estrogen metabolites may identify women who are more likely to develop breast cancer within a population of women with known risk factors
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    urinary estrogen metabolites shown to provide insight into breast cancer risk.  This study suggested that a low 2:16 OHE ratio increase breast cancer risk.
Nathan Goodyear

Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liv... - 0 views

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    Alcohol reduces Akkermansia muciniphila bacteria in the human gut.  Restoration improves Alcoholic liver disease.
Nathan Goodyear

Exploring the Relation of Alcohol Consumption to Risk of Breast Cancer - Am J Epidemiol - 0 views

  • there was a monotonic increase in the relative risk of breast cancer with alcohol consumption
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    up to 10% increase in breast cancer in women who drink alcohol daily
Nathan Goodyear

Alcohol and Breast Cancer, November 7, 2001, Singletary and Gapstur 286 (17): 2143 - JAMA - 0 views

  • The association of alcohol consumption with increased risk for breast cancer has been a consistent finding in a majority of epidemiologic studies during the past 2 decades
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    Increased risk of breast cancer in those who regularly consume alcohol; 
Nathan Goodyear

Current alcohol consumption and its relationship to incident dementia: results from a 3... - 0 views

  • ight-to-moderate alcohol consumption is inversely related to incident dementia
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    light to moderate alcohol intake helps to reduce dementia risk
Nathan Goodyear

Glycine Accelerates Recovery from Alcohol-Induced Liver Injury - 0 views

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    Glycine shortens recovery time in alcohol induced injury.
Nathan Goodyear

Fructose Consumption as a Risk Factor for Non-alcoholic Fatty Liver Disease - 0 views

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    Fructose upregulates fructokinase activity and this increase liver triglyceride production increasing non-alcoholic fatty liver disease also known as NAFLD.
Nathan Goodyear

Alcohol and mitochondria: a dysfunctional relation... [Gastroenterology. 2002] - PubMed... - 0 views

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    excess alcohol and mitochondria don't mix
Nathan Goodyear

Perillyl alcohol: applications in oncology. [Altern Med Rev. 1998] - PubMed result - 0 views

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    Perillyl alcohol inhibits cancer growth and increases cell death in colon, breast, and liver cancer
Nathan Goodyear

Epidemiology of non-alcoholic fatty liver disease. [Dig Dis. 2010] - PubMed result - 0 views

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    non-alcoholic fatty liver disease the result of Metabolic syndrome.  New epidemic associated with obesity. Scary statistics about the children of America.
Nathan Goodyear

Vitamin-Dependent Methionine Metabolism and Alcoholic Liver Disease - 0 views

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    nice article discussing disrupted methionine metabolism and development of Alcoholic Liver Disease
Nathan Goodyear

PLOS ONE: Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein... - 0 views

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    makes sense.  Alcohol impairs recovery from exercise--specifically protein synthesis.
Nathan Goodyear

PLOS ONE: Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein... - 0 views

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    Alcohol in the recovery phase suppresses anabolic repair through inhibition of mTOR--even when taken with protein.
Nathan Goodyear

Risk of Breast Cancer in Relation to Combined Effects of Hormone Th... - PubMed - NCBI - 0 views

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    Study finds increases serum Estradiol and Testosterone levels associated with increased risk of breast cancer.  Increased risk was also found associated with being overweight/obese, increased alcohol intake, alcohol combined with HT.  This was found in estrogen receptor + cases of breast cancer.
Nathan Goodyear

Glucocorticoids plus N-Acetylcysteine in Severe Alcoholic Hepatitis | NEJM - 0 views

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    NAC benefits short-term survival in alcoholic hepatitis, including a drop in bilirubin.
Nathan Goodyear

Effect of Testosterone Administration on Liver Fat in Older Men With Mobility Limitatio... - 0 views

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    Testosterone replacement in older men with low T not shown to improve liver fat content.  This has obvious implications to non-alcoholic hepatic steatosis.
Nathan Goodyear

When and how to evaluate mildly elevated liver enzymes in apparently healthy patients - 0 views

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    with an estimated 25% of Americans with non-alcoholic fatty liver disease (NAFLD), elevated liver enzymes are becoming a more common finding.  Nice review article on what the tests mean and what disease are underlying.
Nathan Goodyear

Nonalcoholic Fatty Liver Disease in Children - 0 views

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    non-alcoholic fatty liver disease is the new epidemic.  But the scary point is NAFLD is found in many of our children.  As goes obesity, so goes NAFLD
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