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Postmenopausal cognitive decline is a common complaint.  Declining Estradiol and progesterone have been implicated, in part, to this cognitive decline.  This study finds that progesterone increases expression of Transthyretin, a protein that processes amyloid Beta protein.  This amyloid Beta protein is associated with damage found in Alzheimer's. 

curcumin and vitamin D synergistic in beta-amyloid removal in Alzheimer's disease. 

Huperzine A, a natural acetylcholinesterase inhibitor, provides neuroprotection through increase mitochondrial function and decrease in accumulated amyloid Beta protein.

elevated insulin levels associated with disordered Beta-amyloid metabolism and hyperphosphorylation of tau proteins.  Free radicals also play a role as well.

low neuronal cholesterol increases risk of neurodegeneration.  Low Cholesterol in neurons increases B-amyloid protein formation.  Are we increasing Alzheimer's incidence by lowering cholesterol too much?  After all, the brain needs cholesterol!

elevated insulin, found in insulin resistance, associated with disordered Beta-amyloid metabolism.

liposomal curcumin reduces Triglycerides and serum beta-amyloid protein.

Curcumin found to provide benefit even in the healthy. This study, though small and very short, found improvement in Triglycerides, salivary amylase, reduced oxidative stress, reduced beta-amyloid protein, increased NO, and reduced liver enzymes.

good review of understanding of how poor glucose control, oxidative stress result in AGE and Alzheimer's disease.

Inflammation plays an important role in Alzheimers disease.  Likewise, the ability to resolve inflammation is altered, as this study shows.  This points to natural therapies i.e. omega-3, curcumin, vitamin D...