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Nathan Goodyear

Lack of association between pe... [J Clin Res Pediatr Endocrinol. 2014] - PubMed - NCBI - 0 views

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    no correlation found between TSH and peripheral thyroid hormones in obese children.
Nathan Goodyear

Changes in Red Meat Consumption and Subsequent Risk of Type 2 Diabetes: Three Cohorts o... - 0 views

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    red meat consumption associated with increased weight and risk of type 2 Diabetes.  The study didn't look at the source of the red meat.  
Nathan Goodyear

A plant-based diet for type 2 diabetes... [Diabetes Educ. 2010 Jan-Feb] - PubMed - NCBI - 0 views

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    low fat, but particularly a plant-based diet reduces body weight and improves glucose control.
Nathan Goodyear

The role of dietary fat in peripheral thyroid hor... [Metabolism. 1980] - PubMed - NCBI - 0 views

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    High fat diet in this small animal study finds an increase in reverse T3 and a decrease in T3.  Higher carbohydrate diet provided no significant change.
Nathan Goodyear

Minireview: Cracking the Metabolic Code for Thyroid Hormone Signaling - 0 views

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    Here is a great review of thyroid hormone metabolism published in the very relevant journal Endocrinology.  The review describes the peripheral metabolism of the pro hormone T4 and the peripheral metabolism to free T3 and/or reverse T3 and the associated metabolic implications.  Why don't more endocrinologists read?This is an animal study.
Nathan Goodyear

Cracking the Code for Thyroid Hormone Signaling - 0 views

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    nice review of thyroid physiology.  Good discussion of peripheral thyroid metabolism.
Nathan Goodyear

Reverse T3 as a parameter of myocardial functi... [Int J Cardiol. 2010] - PubMed - NCBI - 0 views

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    Another study regarding reverse T3 that many Endocrinologists need to read.  In this study, the authors find that significantly higher reverse T3 levels were associated with myocardial function impairment (MFI) class IV.  This MFI class IV was also found associated with a decreased fT3/rT3.
Nathan Goodyear

High-fat diet increases thyrotropin and oxygen... [Endocrinology. 2010] - PubMed - NCBI - 0 views

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    Animal study finds that an 8 week course of high fat diet (HF) is associated with an increase serum rT3 levels by 1.5 fold.
Nathan Goodyear

Relationship of thyroid hormone levels and cardiov... [Endocrine. 2014] - PubMed - NCBI - 0 views

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    Patients with type II Diabetes and h/o of CVE  have higher rT3 in study.  The Endocrinologist that said reverse T3 is completely irrelevant needs to read more studies and stop listening to opinion.
Nathan Goodyear

Risk of Myocardial Infarction in Older Men Receiving Testosterone Therapy - 0 views

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    Testosterone therapy in older men found to provide no increase in MI risk.  In fact, those men with high MI risk, Testosterone provided protection against MI.
Nathan Goodyear

Effects of Long-Term Testosterone Therapy on Patients with "Diabesity": Results of Obse... - 0 views

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    Six years of Testosterone therapy in men with obesity, low T, and type II Diabetes was found to decrease waist circumference, decrease weight, decrease fasting glucose, decrease in HgbA1c and improved systolic/diastolic blood pressure, lipids, CRP, and liver enzymes.
Nathan Goodyear

Estradiol Binds to Insulin and I... [Front Endocrinol (Lausanne). 2014] - PubMed - NCBI - 0 views

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    Interesting.  Estradiol competes with Insulin for insulin receptors.  Estradiol has a high affinity for these Insulin receptors.  This has huge implications on HRT in women and men for that matter.
Nathan Goodyear

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynt... - 0 views

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    In this study, the benefits of Testosterone was found to reduce 5-LO activity.  This has implications in CVD in men.  No evidence was found for 5alpha-DHT.
Nathan Goodyear

Effects of testosterone supplementatio... [Clin Endocrinol (Oxf). 2010] - PubMed - NCBI - 0 views

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    Men with hypogonadism, low T, Testosterone therapy reduced IL-1beta, TNF-alph, and CRP.   In addition, BMI and waist circumference was reduced.  Leptin and insulin decreased as well.
Nathan Goodyear

The effect of statins on testosterone in men and wom... [BMC Med. 2013] - PubMed - NCBI - 0 views

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    Meta-analysis finds that Testosterone lowers Testosterone levels in both men and women.  I love the authors concluding remarks: "whether this is a detrimental side effect..."  in men, there is no doubt.
Nathan Goodyear

The role of testosterone in the m... [J Steroid Biochem Mol Biol. 2009] - PubMed - NCBI - 0 views

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    Testosterone plays an important role in glucose and lipid metabolism.  Thus, low Testosterone, will result in increased disruption in the homeostasis of glucose and lipids resulting in increased weight, insulin resistance, diabetes, metabolic syndrome... Low SHBG was also shown to be associated with MetS
Nathan Goodyear

http://www.scielo.br/pdf/abem/v53n8/02.pdf - 0 views

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    low T associated with increased risk of type II Diabetes and Metabolic Syndrome.
Nathan Goodyear

http://onlinelibrary.wiley.com/store/10.2164/jandrol.108.005751/asset/jandrol.108.00575... - 0 views

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    Pubmed search finds low T associated IR, type II diabetes, Metabolic syndrome, and increased visceral fat in men.
Nathan Goodyear

Thyroid Hormones (T3 and T4): Dual Effect on Human Cancer Cell Proliferation - 0 views

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    The effects of T3 on cancer cell lines varies.  All cell lines came from the same tissue. It doesn't appear that simply stating T3 promotes cellular metabolism and thus provides an increase in cancer progression risk.  Some cell lines studies actually had an inhibition of cell growth, whereas others saw an increase.  
Nathan Goodyear

Arquivos Brasileiros de Endocrinologia & Metabologia - Influence of estradiol and triio... - 0 views

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    Study finds T3 effects on ER-alpha is likely a non-genomic pathway.  This study found a down regulation of ER-alpha in tumor cell lines by T3.
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